Tootfinder

Optimal Pair Matching Combined with Machine Learning Predicts a Significant Reduction in Myocardial Infarction Risk in African Americans following Omega-3 Fatty Acid Supplementation
Shudong Sun, Aki Hara, Laurel Johnstone, Brian Hallmark, Joseph C. Watkins, Cynthia A. Thomson, Susan M. Schembre, Susan Sergeant, Jason Umans, Guang Yao, Hao Helen Zhang, Floyd H. Chilton

Optimal Pair Matching Combined with Machine Learning Predicts a Significant Reduction in Myocardial Infarction Risk in African Americans following Omega-3 Fatty Acid Supplementation
Conflicting clinical trial results on omega-3 highly unsaturated fatty acids (n-3 HUFA) have prompted uncertainty about their cardioprotective effects. While the VITAL trial found no overall cardiovascular benefit from n-3 HUFA supplementation, its substantial African American (AfAm) enrollment provided a unique opportunity to explore racial differences in response to n-3 HUFA supplementation. The current observational study aimed to simulate randomized clinical trial (RCT) conditions by matchi…