Tootfinder

🧁 Tiny sugars in the brain disrupt emotional circuits, fueling depression
#brain

Tiny sugars in the brain disrupt emotional circuits, fueling depression
Depression is a serious disorder that disrupts daily life through lethargy, sleep disturbance, and social withdrawal, and also increases the risk of suicide. The number of depression patients has steadily increased over the years, affecting more than 280 million people worldwide as of 2025. Now, researchers have uncovered a new pathological mechanism that could provide clues for the diagnosis and treatment of depression.

Mud and debris flow due to heavy rain in Montecito.

FYI
* Tornado Warning for...
Central Santa Cruz County in northern California...
* Until 100 PM PST.
* At 1219 PM PST, a severe thunderstorm capable of producing a
tornado was located 7 miles south of Santa Cruz, moving north at 35
mph.
HAZARD...Tornado.
SOURCE...Radar indicated rotation.
IMPACT...Flying debris will be dangerous to those caught without
shelter. Mobile homes will be damaged or destroyed. Damage
to roofs, windows and…

★ Do you get excited or upset about AWS SCPs, or GCP Org Policies?
★ Do you have experience developing software to solve cloud security challenges?
★ Do you downplay your cloud security knowledge but actually you know a lot of niche oddities of cloud IAM?
★ Do you like working in diverse security teams that care about your wellbeing?
★ Do you want to get paid to work on cloud security for one of the most sophisticated AWS environments in the world?
I'm hiring a…

Security Software Engineer (L5), Cloud Infrastructure Security | USA - Remote | Netflix
Netflix is one of the world's leading entertainment services, with over 300 million paid memberships in over 190 countries enjoying TV series, films and games across a wide variety of genres and languages. Members can play, pause and resume watching as much as they want, anytime, anywhere, and can change their plans at any time. Netflix operates our streaming service control plane on Amazon Web Services, which has led to one of the largest and most sophisticated AWS environments in the world. C…

Re: discourse about #FediSoWhite
I'm a white man. Was on Twitter throughout #BLM and gained an awful lot of free education from Black folks on there. That was the start of me consciously following diverse folks which is a strategy that's improved my life immensely.
Back on Twitter before the Muskening, there was a lot of diversity. Black Twitter was a thing, and not just first-world (anyone else remember "O jewa ke eng?"). When I went looking for people to follow to diversify my feed, I found them in abundance.
That's why it's so clearly false to me when people claim that the fediverse is secretly diverse, and why anyone making that claim sounds suspect to me. Sure there are a ton of great Black and other POC folks you can find on here, if you look hard. But it's nowhere near the levels of diversity and community that were on Twitter. Which you would know had you been following those people before, so now I have to assume you weren't, and wonder why you feel qualified to make statements about diversity even though you haven't made an effort to engage with diverse voices before?
Also, if you were actually following some of the excellent POC voices on here, you'd know that across different servers and interest groups, almost every group has had a discussion of #FediSoWhite at some point. If all the Black people you follow are independently talking about the lack of community and diversity here, you've either got to believe them or start putting on your clown makeup, and the later is absolutely a choice.

‘Green’ energy transition leaves a dirty trail in the Philippines’ nickel belt https://news.mongabay.com/2025/11/green-energy-transition-leaves-a-dirty-trail-in-the-philippines-nickel-belt/

‘Green’ energy transition leaves a dirty trail in the Philippines’ nickel belt
MINDANAO, Philippines — Communities living near mining operations in the southern Philippines’ Caraga region are feeling the toll of the global energy transition, with nickel mining driving deforestation and pollution, according to a recent report. Climate Rights International (CRI), the U.S.-based NGO behind the report, highlighted harms to the environment, local livelihoods and public health […]

Im Lauf der Zeit (Kings of the Road) - Wim Wenders - Internet Archive
https://archive.org/details/im-lauf-der-zeit-kings-of-the-road-1976-wim-wenders (1976, 176min, zw-w)
'Rondreizend reparateur van bioscoopprojectoren Bruno (geweldige rol van Vogler) en de depressieve Robert treffen elkaar onder eigenaardige omstandigheden: laatstgenoemde probeert zichzelf in een rivier te verdrinken maar zijn auto zinkt niet, waarna Bruno hem een lift geeft. ...'
https://www.vprogids.nl/cinema/films/film~386547~im-lauf-der-zeit~.html
Aanrader!
Verder alleen bij Mubi te zien.

A broad retreat is underway in the nonprofit world.
After Donald Trump ordered his administration to root out “illegal” diversity, equity and inclusion efforts earlier this year,
opening the door to investigations and funding cuts for offenders,
more than 1,000 charities rewrote their mission statements in forms they filed this year with the Internal Revenue Service,
removing or minimizing language tied to race, inequity and historically disadvantaged communities.<…

Deleting DEI
As the Trump administration ordered agencies to eradicate “illegal” diversity, equity and inclusion efforts, we identified more than 1,000 nonprofits that removed such language from the mission statements in their tax filings.

"Iyengar told me she isn’t worried about Musk ruining D&D.
Musk is welcome to waste his money on “trying to make everyone play the version of D&D that he thinks should exist in the world,” Iyengar said. “That’s never been how that works. Everyone will play it how they want, or they’ll play something else.”
https://

Meta’s 2020 research project, Project Mercury,
measured the effect of ‘deactivating’ Facebook & Instagram
According to Meta docs obtained via discovery…
’people who stopped using Facebook for a week reported lower feelings of depression, anxiety, loneliness & social comparison’
https://