Tootfinder

MSRepaint: Multiple Sclerosis Repaint with Conditional Denoising Diffusion Implicit Model for Bidirectional Lesion Filling and Synthesis
Jinwei Zhang, Lianrui Zuo, Yihao Liu, Hang Zhang, Samuel W. Remedios, Bennett A. Landman, Peter A. Calabresi, Shiv Saidha, Scott D. Newsome, Dzung L. Pham, Jerry L. Prince, Ellen M. Mowry, Aaron Carass
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MSRepaint: Multiple Sclerosis Repaint with Conditional Denoising Diffusion Implicit Model for Bidirectional Lesion Filling and Synthesis
In multiple sclerosis, lesions interfere with automated magnetic resonance imaging analyses such as brain parcellation and deformable registration, while lesion segmentation models are hindered by the limited availability of annotated training data. To address both issues, we propose MSRepaint, a unified diffusion-based generative model for bidirectional lesion filling and synthesis that restores anatomical continuity for downstream analyses and augments segmentation through realistic data gene…