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Uncertainty Quantification of Bacterial Microcompartment Permeability
Andre Archer, Brett J. Palmero, Charlotte Abrahamson, Carolyn E. Mills, Nolan W. Kennedy, Danielle Tullman-Ercek, Niall M. Mangan
https://arxiv.org/abs/2509.23445

Uncertainty Quantification of Bacterial Microcompartment Permeability
$\textit{Salmonella}$ expresses bacterial microcompartments (MCPs) upon 1,2-propanediol exposure. MCPs are nanoscale protein-bound shells that encase enzymes for the cofactor-dependent 1,2-propanediol metabolism. They are hypothesized to limit exposure to the toxic intermediate, propionaldehyde, decrease cofactor involvement in competing reactions, and enhance flux. We construct a mass-action mathematical model of purified MCPs and calibrate parameters to measured metabolite concentrations. We …

Wie bringe ich jetzt dem freundlichen Menschen bei, dass er an seine Preisvorstellung zwei Nullen anhängen kann?
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