Tootfinder

Heterogeneous Entity Representation for Medicinal Synergy Prediction
Jiawei Wu, Jun Wen, Mingyuan Yan, Anqi Dong, Can Chen
https://arxiv.org/abs/2406.10778

Heterogeneous Entity Representation for Medicinal Synergy Prediction
Medicinal synergy prediction is a powerful tool in drug discovery and development that harnesses the principles of combination therapy to enhance therapeutic outcomes by improving efficacy, reducing toxicity, and preventing drug resistance. While a myriad of computational methods has emerged for predicting synergistic drug combinations, a large portion of them may overlook the intricate, yet critical relationships between various entities in drug interaction networks, such as drugs, cell lines,…

Heterogeneous Entity Representation for Medicinal Synergy Prediction
Jiawei Wu, Jun Wen, Mingyuan Yan, Anqi Dong, Can Chen
https://arxiv.org/abs/2406.10778

Heterogeneous Entity Representation for Medicinal Synergy Prediction
Medicinal synergy prediction is a powerful tool in drug discovery and development that harnesses the principles of combination therapy to enhance therapeutic outcomes by improving efficacy, reducing toxicity, and preventing drug resistance. While a myriad of computational methods has emerged for predicting synergistic drug combinations, a large portion of them may overlook the intricate, yet critical relationships between various entities in drug interaction networks, such as drugs, cell lines,…