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MATRIX: Multi-Agent simulaTion fRamework for safe Interactions and conteXtual clinical conversational evaluation
Ernest Lim, Yajie Vera He, Jared Joselowitz, Kate Preston, Mohita Chowdhury, Louis Williams, Aisling Higham, Katrina Mason, Mariane Melo, Tom Lawton, Yan Jia, Ibrahim Habli
https://arxiv.org/abs/2508.19163

MATRIX: Multi-Agent simulaTion fRamework for safe Interactions and conteXtual clinical conversational evaluation
Despite the growing use of large language models (LLMs) in clinical dialogue systems, existing evaluations focus on task completion or fluency, offering little insight into the behavioral and risk management requirements essential for safety-critical systems. This paper presents MATRIX (Multi-Agent simulaTion fRamework for safe Interactions and conteXtual clinical conversational evaluation), a structured, extensible framework for safety-oriented evaluation of clinical dialogue agents. MATRIX …