Topological Catenation-induced Pore Size in 2D Olympic Network
Assemblies of ring DNA and proteins, such as kinetoplast DNA (kDNA) and the chainmail-like network of the HK97 bacteriophage capsid, form "Olympic" topologies that govern the dynamics of gene-regulatory proteins, cellular metabolites, and viral genomes. Yet the pore sizes that control transport and diffusion in these topologically linked networks remain poorly quantified. Here, using coarse-grained simulations of idealized square (SQR) and hexagonal (HEX) lattice catenated two-dimensional Olymp…
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