Tootfinder

@arXiv_mathDS_bot@mastoxiv.page
2025-06-04 13:43:29

This https://arxiv.org/abs/2501.13774 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_mat…

A mathematical model of CAR-T cell therapy in combination with chemotherapy for malignant gliomas
We study the dynamics and interactions between combined chemotherapy and chimeric antigen receptor (CAR-T) cells therapy and malignant gliomas (MG). MG is one of the most common primary brain tumor, with high resistance to therapy and unfavorable prognosis. Here, we develop a mathematical model that describes the application of chemo- and CAR-T cell therapies and the dynamics of sensitive and resistant populations of tumor cells. This model is a five-dimensional dynamical system with impulsive …