Tootfinder

Revisiting the topic of Up and Down states in striatal spiny projection neurons after ages. Anyone have a good reference (or unpublished pet theory) on the functions they might enable for basal ganglia circuits?
http://www.scholarpedia.org/article/Up_and_down_states

Quantitative Analysis of Roles of Direct and Indirect Pathways for Action Selection in The Basal Ganglia
Sang-Yoon Kim, Woochang Lim
https://arxiv.org/abs/2404.13888

Quantitative Analysis of Roles of Direct and Indirect Pathways for Action Selection in The Basal Ganglia
The basal ganglia (BG) show diverse functions for motor and cognition. Here, we are concerned about action selection performed by the BG. Particularly, we make quantitative analysis of roles of direct pathway (DP) and indirect pathway (IP) for action selection in a spiking neural network with 3 competing channels. For such quantitative work, in each channel, we get the competition degree ${\cal C}_d$, given by the ratio of strength of DP (${\cal S}_{DP}$) to strength of IP (${\cal S}_{IP}$) (i.…

CBGT-Net: A Neuromimetic Architecture for Robust Classification of Streaming Data
Shreya Sharma, Dana Hughes, Katia Sycara
https://arxiv.org/abs/2403.15974

CBGT-Net: A Neuromimetic Architecture for Robust Classification of Streaming Data
This paper describes CBGT-Net, a neural network model inspired by the cortico-basal ganglia-thalamic (CBGT) circuits found in mammalian brains. Unlike traditional neural network models, which either generate an output for each provided input, or an output after a fixed sequence of inputs, the CBGT-Net learns to produce an output after a sufficient criteria for evidence is achieved from a stream of observed data. For each observation, the CBGT-Net generates a vector that explicitly represents th…

Implementation of a Model of the Cortex Basal Ganglia Loop
Naoya Arakawa
https://arxiv.org/abs/2402.13275 https://arxiv.org/pdf/2402.…

Implementation of a Model of the Cortex Basal Ganglia Loop
This article presents a simple model of the cortex-basal ganglia-thalamus loop, which is thought to serve for action selection and executions, and reports the results of its implementation. The model is based on the hypothesis that the cerebral cortex predicts actions, while the basal ganglia use reinforcement learning to decide whether to perform the actions predicted by the cortex. The implementation is intended to be used as a component of models of the brain consisting of cortical regions o…

Molecular Communication-Based Intelligent Dopamine Rate Modulator for Parkinson's Disease Treatment
Elham Baradari and, Ozgur B Akan
https://arxiv.org/abs/2403.16564

Molecular Communication-Based Intelligent Dopamine Rate Modulator for Parkinson's Disease Treatment
Parkinson's disease (PD) is a progressive neurodegenerative disease, and it is caused by the loss of dopaminergic neurons in the basal ganglia (BG). Currently, there is no definite cure for PD, and available treatments mainly aim to alleviate its symptoms. Due to impaired neurotransmitter-based information transmission in PD, molecular communication-based approaches can be employed as potential solutions to address this issue. Molecular Communications (MC) is a bio-inspired communication method…

This https://arxiv.org/abs/2310.11635 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_qbi…

Break-up and Recovery of Harmony between Direct and Indirect Pathways in The Basal Ganglia; Huntington's Disease and Treatment
The basal ganglia (BG) in the brain exhibit diverse functions for motor, cognition, and emotion. Such BG functions could be made via competitive harmony between the two competing pathways, direct pathway (DP) (facilitating movement) and indirect pathway (IP) (suppressing movement). As a result of break-up of harmony between DP and IP, there appear pathological states with disorder for movement, cognition, and psychiatry. In this paper, we are concerned about the Huntington's disease (HD), which…

This https://arxiv.org/abs/2309.12540 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_qbi…

Quantifying Harmony between Direct and Indirect Pathways in The Basal Ganglia; Healthy and Parkinsonian States
The basal ganglia (BG) show a variety of functions for motor and cognition. There are two competitive pathways in the BG; direct pathway (DP) which facilitates movement and indirect pathway (IP) which suppresses movement. It is well known that diverse functions of the BG may be made through "balance" between DP and IP. But, to the best of our knowledge, so far no quantitative analysis for such balance was done. In this paper, as a first time, we introduce the competition degree ${\cal C}_d$ bet…