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The enteric nervous system is 10 times stiffer than the brain
Nicolas R. Chevalier (IJPB), Alexis Peaucelle (IJPB), Thomas Guilbert (IC UM3), Pierre Bourdoncle, Wang Xi
https://arxiv.org/abs/2506.08583

The enteric nervous system is 10 times stiffer than the brain
Neural tissues of the central nervous system are among the softest and most fragile in the human body, protected from mechanical perturbation by the skull and the spine. In contrast, the enteric nervous system is embedded in a compliant, contractile tissue and subject to chronic, high-magnitude mechanical stress. Do neurons and glia of the enteric nervous system display specific mechanical properties to withstand these forces? Using nano-indentation combined with immunohistochemistry and second…