Tootfinder

Is a field programmable gender array one of those microfluidic lab-on-a-chip thingies, but for doing experiments with gender fluid?
That would certainly explain some of the demographics of FPGA folks.

Viscoelastic properties of tumor spheroids revealed by a microfluidic compression device and a modified power law model
Mrinal Pandey, Bangguo Zhu, Kaitlyn Roach, Young Joon Suh, Jeffrey E Segall, Chung-Yuen Hui, Mingming Wu
https://arxiv.org/abs/2509.17294

Viscoelastic properties of tumor spheroids revealed by a microfluidic compression device and a modified power law model
Clinically, palpation is one of the important diagnostic methods to assess tumor malignancy. In laboratory research, it is well accepted that the bulk stiffness of the tumor and the surrounding tissue is closely correlated with the malignant state of the tumor. Here, we postulate that, in addition to tumor stiffness, tumor viscoelasticity - the fact that tumor tissue takes time to bounce back after compression, can also be used to evaluate the tumor malignancy state. In this work, we characteri…

Insect-Wing Structured Microfluidic System for Reservoir Computing
Jacob Clouse (School of Computing, University of Nebraska-Lincoln, Lincoln, Nebraska, USA), Thomas Ramsey (Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln, Lincoln, Nebraska, USA), Samitha Somathilaka (School of Computing, University of Nebraska-Lincoln, Lincoln, Nebraska, USA), Nicholas Kleinsasser (School of Computing, University of Nebraska-Lincoln, Lincoln, Nebraska, USA), Sangjin …

Insect-Wing Structured Microfluidic System for Reservoir Computing
As the demand for more efficient and adaptive computing grows, nature-inspired architectures offer promising alternatives to conventional electronic designs. Microfluidic platforms, drawing on biological forms and fluid dynamics, present a compelling foundation for low-power, high-resilience computing in environments where electronics are unsuitable. This study explores a hybrid reservoir computing system based on a dragonfly-wing inspired microfluidic chip, which encodes temporal input pattern…

Numerical analysis of controlled droplet formation surrounded by shear-thinning fluid in a co-flow microfluidic device
Manohar Jammula, Somasekhara Goud Sontti
https://arxiv.org/abs/2507.11917

Numerical analysis of controlled droplet formation surrounded by shear-thinning fluid in a co-flow microfluidic device
In this work, we used a coupled level set and volume of fluid (CLSVOF) computational method for studying the generation of microdroplets in a two dimensional circular co-flow microfluidic device. The fundamental understanding of shear thinning behavior on controlled droplet formation in a microchannel is systematically investigated. Droplet generation and dynamics are controlled by altering the operating conditions and fluid properties, such as CMC solution concentration, both fluids flow rates…

Optimized Designs for High-Efficiency Particle Sorting in Serpentine Microfluidic Channels
Sayan Karmakar, Anish Pal, Sourav Sarkar, Achintya Mukhopadhyay
https://arxiv.org/abs/2509.10998

Optimized Designs for High-Efficiency Particle Sorting in Serpentine Microfluidic Channels
Efficient particle sorting in microfluidic systems is vital for advancements in biomedical diagnostics and industrial applications. This study numerically investigates particle migration and passive sorting in symmetric serpentine microchannels, leveraging inertial and centrifugal forces for label-free, high-throughput separation. Using a two-dimensional numerical model, particle dynamics were analyzed across varying flow rates, diameter ratios (1.2, 1.5, and 2), and channel configurations. The…

Photonic bandgap properties of hyperuniform systems self-assembled in a microfluidic channel
Lily Traktman, Bowen Yu, Isa Vasquez, Stanislav Ospov, Remi Dreyfus, Weining Man
https://arxiv.org/abs/2507.08613

Photonic bandgap properties of hyperuniform systems self-assembled in a microfluidic channel
Traditional self-assembly methods often rely on densely packed colloidal crystalline structures and have inherent limitations in generating materials with isotropic photonic bandgaps (PBG). This study explores the photonic properties of materials structured according to hyperuniform disordered patterns (HUDS) generated via a hydrodynamic process in a microchannel. This research employs simulations to characterize optical bandgaps and determine the minimum dielectric contrast required for PBG fo…

Fully integrated automatic reusable microfluidic setup for immobilization, analysis and non-selective release of particles
Alexandre Chargueraud, Lars Kool, Jacques Fattaccioli
https://arxiv.org/abs/2507.06241

Fully integrated automatic reusable microfluidic setup for immobilization, analysis and non-selective release of particles
We present a microfluidic device that enables trapping, analysis, and on-demand release of individual microparticles through membrane deformation driven by pneumatic actuation. Inspired by Pachinko-style architectures, the system features an array of traps supported by a deformable PDMS membrane, actuated via pressure control in a pneumatic chamber bonded above. Unlike conventional rigid designs, our configuration enhances membrane flexibility using a wide elliptical cavity and suspended rectil…

Crosslisted article(s) found for cs.ET. https://arxiv.org/list/cs.ET/new
[1/1]:
- Insect-Wing Structured Microfluidic System for Reservoir Computing
Clouse, Ramsey, Somathilaka, Kleinsasser, Ryu, Balasubramaniam

A mother-machine microfluidic device for non-adherent mammalian cells reveals the population growth strategies
Simone Scalise, Giovanna Peruzzi, Davide Caprini, Giorgio Gosti, Giancarlo Ruocco, Mattia Miotto
https://arxiv.org/abs/2509.06113

A mother-machine microfluidic device for non-adherent mammalian cells reveals the population growth strategies
We develop a mother machine-like microfluidic device specifically designed to track the proliferation of T-cells via live-cell microscopy. Although numerous microfluidic setups have been developed to study cell proliferation at the single-cell level, most of them are optimized for use on adherent cells. Here, we present a device to track the proliferation of suspension cells, featuring an array of microchannels that trap cells, easing their monitoring while allowing for controlled growth condit…

Microfluidic studies of Salt Precipitation: Influence of Brine Composition, Interfacial Tension, Flow Conditions, and Chemical Additives
Karol M. D\k{a}browski, Mohammad Nooraiepour, Mohammad Masoudi, Ahsan N. Soomro, Rafa{\l} Smulski, Jan Barbacki, Helge Hellevang, Stanis{\l}aw Nagy
https://arxiv.org/abs/2507.20638

Microfluidic studies of Salt Precipitation: Influence of Brine Composition, Interfacial Tension, Flow Conditions, and Chemical Additives
This study investigates the interfacial tension, fluid mobility, and crystallization behavior of various saline and additive-modified solutions in a microfluidic chip environment, simulating pore-scale processes during CO2 injection. The brine compositions included NaCl solutions at different concentrations, surfactant-modified fluids, alcohol-water mixtures, and ammonia solutions. Microfluidic experiments were performed on a range of flow rates and the dynamics of CO2 breakthrough, brine evapo…

Pose-Free 3D Quantitative Phase Imaging of Flowing Cellular Populations
Enze Ye, Wei Lin, Shaochi Ren, Yakun Liu, Xiaoping Li, Hao Wang, He Sun, Feng Pan
https://arxiv.org/abs/2509.04848

Pose-Free 3D Quantitative Phase Imaging of Flowing Cellular Populations
High-throughput 3D quantitative phase imaging (QPI) in flow cytometry enables label-free, volumetric characterization of individual cells by reconstructing their refractive index (RI) distributions from multiple viewing angles during flow through microfluidic channels. However, current imaging methods assume that cells undergo uniform, single-axis rotation, which require their poses to be known at each frame. This assumption restricts applicability to near-spherical cells and prevents accurate …

Electrical Impedance Tomography with an Integrated Picoliter-Volume Subtractive Microfluidic Chamber in 65 nm CMOS
Antonio Victor Machado de Oliveira, Debjit Sarkar, Ali Hajimiri
https://arxiv.org/abs/2508.20431

Electrical Impedance Tomography with an Integrated Picoliter-Volume Subtractive Microfluidic Chamber in 65 nm CMOS
Electrical impedance tomography with fully integrated microfluidics and electronics is presented for the first time in a CMOS chip. Chambers and electrodes are fabricated in the interconnect layers of a 65 nm CMOS chip through post-processing, enabling picoliter-volumes to be processed and imaged. Tomography maps are reconstructed by reading out voltages from a 16-element electrode array and processing the data off-chip, and sources of variation in reconstruction are discussed. The EIT system p…

Latent Space-Driven Quantification of Biofilm Formation using Time Resolved Droplet Microfluidics
Daniela P\'erez Guerrero, Jes\'us Manuel Ant\'unez Dom\'inguez, Aur\'elie Vigne, Daniel Midtvedt, Wylie Ahmed, Lisa D. Muiznieks, Giovanni Volpe, Caroline Beck Adiels
https://arxiv.org/abs/2507.07632

Latent Space-Driven Quantification of Biofilm Formation using Time Resolved Droplet Microfluidics
Bacterial biofilms play a significant role in various fields that impact our daily lives, from detrimental public health hazards to beneficial applications in bioremediation, biodegradation, and wastewater treatment. However, high-resolution tools for studying their dynamic responses to environmental changes and collective cellular behavior remain scarce. To characterize and quantify biofilm development, we present a droplet-based microfluidic platform combined with an image analysis tool for i…

Diffusioosmotic flow in a soft microfluidic configuration induces fluid-structure instability
Nataly Maroundik, Dotan Ilssar, Evgeniy Boyko
https://arxiv.org/abs/2507.19065 http…

Diffusioosmotic flow in a soft microfluidic configuration induces fluid-structure instability
Diffusioosmotic flow arises in microfluidic configurations due to solute concentration gradients. In soft microfluidic channels, internal pressure gradients generated by diffusioosmotic flow to conserve mass result in elastic deformation of the channel walls, triggering fluid-structure interaction. In this work, we analyze the fluid-structure interaction between diffusioosmotic flow of an electrolyte solution and a deformable microfluidic channel. We provide insight into the physical behavior o…

An Integrated Lab on a CD Microfluidic Platform for High-Efficiency Blood Cell Separation and Passive Mixing
Reza Lotfi Navaei, Haniyeh Tehrani
https://arxiv.org/abs/2507.01977

An Integrated Lab on a CD Microfluidic Platform for High-Efficiency Blood Cell Separation and Passive Mixing
Blood accounts for 7-8% of total body weight, with an average adult containing 4.5 to 6 quarts. It delivers oxygen and nutrients to cells, removes waste products, supports immunity, and regulates body temperature. Comprising over 4,000 components, including plasma, platelets, erythrocytes, and leukocytes, blood presents a challenge for isolating specific cell types due to its heterogeneity. In autologous therapies, target cells may be as rare as one per million background cells. This study pres…

Nano Machine Intelligence: From a Communication Perspective
Sangjun Hwang, Bon-Hong Koo, Ho Joong Kim, Jang-Yeon Kwon, Chan-Byoung Chae
https://arxiv.org/abs/2509.02235 https://…

Nano Machine Intelligence: From a Communication Perspective
We present an AI-integrated molecular communication link validated on a benchtop nanomachine testbed representative of subdermal implants. The system employs an indium-gallium-zinc-oxide electrolyte-gated FET (IGZO-EGFET) functionalized with glucose oxidase as a biocompatible receiver, a microfluidic channel with a syringe-pump transmitter using on-off keying (OOK), and a machine-intelligence pipeline that addresses model mismatch and hardware non-idealities. The pipeline integrates: (i) a modu…

A Microfluidic Platform for Actin-Based Membrane Remodeling Reveals the Stabilizing Role of Branched Actin Networks on Lipid Microdomains
Lixin Huang (LAMBE - UMR 8587), Rog\'erio Lopes dos Santos (LAMBE - UMR 8587), Sid Labdi (UEVE, LAMBE - UMR 8587, IUT D'EVRY), Guillaume Lamour (LAMBE - UMR 8587, UEVE), Olek Maciejak (SABNP, LAMBE - UMR 8587), Michel Malo (LAMBE - UMR 8587), John Manzi (LPTMS, PMMH), Martin Lenz (LPTMS, PMMH), Jacques Fattaccioli (IPGG, PASTEUR), Cl\'eme…

A Microfluidic Platform for Actin-Based Membrane Remodeling Reveals the Stabilizing Role of Branched Actin Networks on Lipid Microdomains
Cell shape changes, essential for processes such as motility or division, are controlled by the actomyosin cortex that actively remodels biological membranes. Their mechanisms can be deciphered in___vitro using biomimetic reconstituted systems, such as giant unilamellar vesicles (GUVs) with controlled lipid composition coupled to reconstituted actin networks. These assays allow mimicking cell shape changes in controlled biochemical and biophysical environments. However, studying the dynamics of…

A Mini Review on Tumor Organoid-on-a-Chip Technologies in Personalized Oncology
Keyvan Alavi
https://arxiv.org/abs/2507.21149 https://arxiv.org/pdf/2507.21…

A Mini Review on Tumor Organoid-on-a-Chip Technologies in Personalized Oncology
Tumor organoid-on-a-chip platforms represent a cutting-edge fusion of patient-derived organoids with microfluidic technologies, offering unprecedented capabilities for personalized cancer research. These systems overcome limitations of conventional models by enabling precise control over the tumor microenvironment, including nutrient gradients, fluid flow, and immune interactions. Tumor organoids recapitulate patient-specific tumor heterogeneity and genetic landscapes, while microfluidic chips …

Design, Simulation, and Fabrication of a Hexagonal Microfluidic Platform for Culturing Neurons
Maxx Yung
https://arxiv.org/abs/2508.00425 https://arxiv.org…

Design, Simulation, and Fabrication of a Hexagonal Microfluidic Platform for Culturing Neurons
Developing an organoid computing platform from neurons in vitro demands stable, precisely controlled microenvironments. To address this requirement, we designed, simulated, and fabricated a microfluidic device featuring hexagonal wells ($34.64\,\mathrm{μm}$ side length) in a honeycomb array connected by $20\,\mathrm{μm}$ channels. Computational fluid dynamics (CFD) modeling, validated by high mesh quality ($0.934$ orthogonal quality) and robust convergence, confirmed the architecture supports…

High-throughput controlled droplets generation through a flow-focusing microchannel in shear-thinning fluids
Manohar Jammula, Somasekhara Goud Sontti
https://arxiv.org/abs/2507.12048

High-throughput controlled droplets generation through a flow-focusing microchannel in shear-thinning fluids
This study presents a three-dimensional transient computational fluid dynamics simulation of droplet generation in a flow-focusing microfluidic device using the Coupled Level Set and Volume of Fluid method for interface capturing. We systematically investigated the effects of shear-thinning non-Newtonian fluids, specifically carboxymethyl cellulose solutions, on the generation of mineral oil droplets. The rheological properties of carboxymethyl cellulose were analyzed at concentrations of 0.1%,…

Unlocking Surfactant Synergies for Fluorine Replacements: A Microfluidic Exploration of Emulsion Stability and Coalescence Dynamics
Rana Bachnak, Cari Dutcher
https://arxiv.org/abs/2507.17894

Unlocking Surfactant Synergies for Fluorine Replacements: A Microfluidic Exploration of Emulsion Stability and Coalescence Dynamics
Fluorinated surfactants are widely utilized in various applications, including firefighting foams, coatings, and lubricants. Their wide utility is due to their unique properties, such as their ability to effectively lower surface/interfacial tension. However, the excessive use of fluorinated surfactants has raised environmental and health concerns due to their persistence in the environment and potential toxicity. The need for effective and sustainable surfactant replacements has therefore beco…

A microfluidic band-pass filter for flexible fiber separation
Li Zhibo, Bielinski Cl\'ement, Lindner Anke, Delmotte Blaise, du Roure Olivia
https://arxiv.org/abs/2508.19166 …

A microfluidic band-pass filter for flexible fiber separation
The control of particle trajectories in structured microfluidic environments has significantly advanced sorting technologies, most notably through deterministic lateral displacement (DLD). While previous work has largely targeted rigid, near-spherical particles, the sorting of flexible, anisotropic objects such as fibers remains largely unexplored. Here, we combine experiments and simulations to demonstrate how tilted pillar arrays enable efficient, length-based separation of flexible fibers. W…

Ultrasensitive Label-free Detection of Human CEACAM5 using a WGM Resonator Based on Thin-walled Capillary
Xiaolu Cui, Jiyang Ma, Hao Wu, Shuoying Zhao, Xubiao Peng, Chuyu Li, Ruiqi Ming, Qing Zhao
https://arxiv.org/abs/2508.16058

Ultrasensitive Label-free Detection of Human CEACAM5 using a WGM Resonator Based on Thin-walled Capillary
Whispering gallery mode (WGM) laser sensors, utilizing the interaction between the in-plane evanescent field and the surface vicinity, provide enhanced sensitivity in label-free sensing for bioanalysis and disease screening. However, the unavoidably excited spiral modes resulting from the weak axial confinement and their sensing potential were overlooked. In this study, a microfluidic biosensor using the localized conical modes of an active resonator based on the thin-walled capillaries was dev…

Numerical study of freezing efficiency for a moving droplet in the microchannel
Dahu Li, zhiliang Wang
https://arxiv.org/abs/2508.06003 https://arxiv.org/p…

Numerical study of freezing efficiency for a moving droplet in the microchannel
In microfluidic devices, droplets serving as carriers for chemical reactors or biomass can form stably encapsulated particles during the freezing process, holding significant importance in pharmaceuticals and microchemical reaction control. This study couples the Volume of Fluid (VOF) method with an enthalpy-porous media phase change model to distinguish the water (ice)-oil two-phase system and the water-ice two-phase system, respectively.The simulation reveals two distinct solidification patte…

Particle manipulation by hydrodynamic effects in vortical Stokes flow
Xuchen Liu, Sascha Hilgenfeldt
https://arxiv.org/abs/2508.03894 https://arxiv.org/pdf…

Particle manipulation by hydrodynamic effects in vortical Stokes flow
The main motivation of this work is the quantitative prediction and description of particle manipulation (displacement across streamlines) in microfluidic flow. Much attention has been paid recently to placing particles in fast oscillatory flow fields, usually driven by microbubbles actuated by low-frequency ultrasound, where particle inertia leads to deterministic displacements. However, such devices invariably set up simultaneous streaming flows that are interpretable as driven Stokes flows. …

Transient dispersion in oscillatory flows: auxiliary-time extension method for concentration moments
Weiquan Jiang, Guoqian Chen
https://arxiv.org/abs/2507.01870

Transient dispersion in oscillatory flows: auxiliary-time extension method for concentration moments
The dispersion phenomenon of mass and heat transport in oscillatory flows has wide applications in environmental, physiological and microfluidic flows. The method of concentration moments is a powerful theoretical tool for analyzing transport characteristics and is well-developed for steady flows. However, the general solutions of moments derived by Barton (J. Fluid Mech., vol. 126, 1983, pp. 205-218) cannot be applied directly to unsteady flows. Prior studies needed to re-solve the governing e…

Kelvin-Helmholtz instability in binary fluids with miscibility gap
Anubhav Dubey, Sakir Amiroudine
https://arxiv.org/abs/2509.02400 https://arxiv.org/pdf/2…

Kelvin-Helmholtz instability in binary fluids with miscibility gap
The isothermal spatio-temporal evolution of an interface between binary fluids, with temperature sensitive miscibility gap, subjected to shear flow is investigated using direct numerical simulations. The thermophysical properties and the interfacial tension in such fluids exhibit a dynamic temperature dependence based on the degree of miscibility. These fluid pairs can therefore be deployed in crucial microfluidic applications involving enhancement of liquid-liquid mass transfer. In this study,…

Replaced article(s) found for physics.flu-dyn. https://arxiv.org/list/physics.flu-dyn/new
[1/1]:
- On-demand microfluidic droplet pinching and splitting under local confinement gradients
Margaux Kerdraon, Albane Th\'ery, Marc Pascual, St\'ephanie Descroi…