Tootfinder

Modes of Mechanical Guidance of Adhesion-Independent Cell Migration
Hanna Luise Gertack, Peter A. E. Hampshire, Claudia Wohlgemuth, Ricard Alert, Sebastian Aland
https://arxiv.org/abs/2509.11801

Modes of Mechanical Guidance of Adhesion-Independent Cell Migration
Adhesion-independent migration is a prominent mode of cell motility in confined environments, yet the physical principles that guide such movement remain incompletely understood. We present a phase-field model for simulating the motility of deformable, non-adherent cells driven by contractile surface instabilities of the cell cortex. This model couples surface and bulk hydrodynamics, accommodates large shape deformations and incorporates a diffusible contraction-generating molecule (myosin) tha…

Dynamics and rupture of doped Motility Induced Phase Peparation
Rodrigo Fern\'andez-Quevedo Garc\'ia, Enrique Chac\'on, Pedro Tarazona, Chantal Valeriani
https://arxiv.org/abs/2508.05768

Dynamics and rupture of doped Motility Induced Phase Peparation
Adding a small amount of passive (Brownian) particles to a two-dimensional dense suspension of repulsive active Brownian particles does not affect the appearance of a motility-induced phase separation into a dense and a dilute phase, caused by the persistence of the active particles' direction of motion. Unlike a purely active suspension, the dense slab formed in an elongated system of a passive-active mixture may show, over long periods of time, a stable and well-defined propagation of the int…

Jamming of active particles in narrow pores: Implications for ratchet effect and diffusion coefficient
\v{S}imon Pajger, Franti\v{s}ek Slanina
https://arxiv.org/abs/2508.10483 h…

Jamming of active particles in narrow pores: Implications for ratchet effect and diffusion coefficient
We study the behavior of colloidal active particles interacting via steric repulsion in various quasi-1D geometries. We mainly focus on active particles with high Péclet number. We discuss 3 phenomena closely tied to those systems: motility-induced phase separation (or dynamical freezing), ratchet effect (which takes place if the geometry has broken spatial symmetry), and the enhanced diffusion coefficient. We study those particles using numerical simulations employing an ASEP-like model. Besi…

Pressure in active matter
Guo Yu, Ruiyao Li, Fukang Li, Jiayu Zhang, Xiyue Li, Zequ Chen, Joscha Mecke, Yongxiang Gao
https://arxiv.org/abs/2508.09496 https://

Pressure in active matter
In the last decade, the study of pressure in active matter has attracted growing attention due to its fundamental relevance to nonequilibrium statistical physics. Active matter systems are composed of particles that consume energy to sustain persistent motion, which are inherently far from equilibrium. These particles can exhibit complex behaviors, including motility-induced phase separation, density-dependent clustering, and anomalous stress distributions, motivating the introduction of active…

Binary Mixtures in Linear Convection Arrays
Pulak Kumar Ghosh, Yuxin Zhou, Yunyun Li, Fabio Marchesoni, Franco Nori
https://arxiv.org/abs/2508.09902 https://

Binary Mixtures in Linear Convection Arrays
We numerically investigated the dynamics of a mixture of finite-size active and passive particles in a linear array of convection rolls. The interplay of advection and steric interactions produces a number of interesting effects, like the stirring of a passive colloidal fluid by a small fraction of slow active particles, or the separation of the mixture active and passive colloidal fractions by increasing the motility of the active one, which eventually clusters in stagnation areas along the ar…

Stabilizing by steering: Enhancing bacterial motility by non-uniform diffusiophoresis
Viet Sang Doan, Ali Nikkhah, Sangwoo Shin
https://arxiv.org/abs/2509.25770 https://

Stabilizing by steering: Enhancing bacterial motility by non-uniform diffusiophoresis
Bacteria are often required to navigate across confined spaces to reach desired destinations in biological and environmental systems, allowing critical functions in host-microbe symbiosis, infection, drug delivery, soil ecology, and soil bioremediation. While the canonical run-and-tumble motility is effective in finding targets under confinement, it may not represent the most ideal strategy due to the continuous monitoring of environmental cues and stochastic recorrection of their paths. Here, …

Structured Interactions Drive Abrupt Transitions in the Spatial Organization of Microbial Communities
Mattia Mattei, David Soriano Pa\~nos, Mahantesh Halappanavar, Alex Arenas
https://arxiv.org/abs/2509.01365

Structured Interactions Drive Abrupt Transitions in the Spatial Organization of Microbial Communities
Bacteria possess diverse mechanisms to regulate their motility in response to environmental and physiological signals, enabling them to navigate complex habitats and adapt their behavior. Among these mechanisms, interspecies recognition enables cells to modulate their movement based on the ecological identity of neighboring species. Here, we introduce a model in which we assume bacterial species recognizes each other and interact via local signals that either enhance or suppress the motility of…

Electromechanical computational model of the human stomach
Maire S. Henke, Sebastian Brandstaeter, Sebastian L. Fuchs, Roland C. Aydin, Alessio Gizzi, Christian J. Cyron
https://arxiv.org/abs/2509.02486

Electromechanical computational model of the human stomach
The stomach plays a central role in digestion through coordinated muscle contractions, known as gastric peristalsis, driven by slow-wave electrophysiology. Understanding this process is critical for treating motility disorders such as gastroparesis, dyspepsia, and gastroesophageal reflux disease. Computer simulations can be a valuable tool to deepen our understanding of these disorders and help to develop new therapies. However, existing approaches often neglect spatial heterogeneity, fail to c…

Millions impacted by data breaches at insurance giant, auto dealership software firm https://therecord.media/millions-impacted-by-data-breaches-insurance-car-dealership-software

Analysis of a Cross-Nonlinear Porous-Medium System Modeling Pressure-Driven Cell Population Dynamics
Alexis B\'ejar-L\'opez, Rafael Granero-Belinch\'on, Carlos Pulido, Juan Soler
https://arxiv.org/abs/2507.23680

Analysis of a Cross-Nonlinear Porous-Medium System Modeling Pressure-Driven Cell Population Dynamics
In this work, we introduce a cross-diffusion model that couples population density and occupied area to investigate how internal pressure drives growth and motility. By blending nonlinear nonlocal interactions with porous-medium diffusion and an antidiffusive pressure term, the model captures the two-way feedback between local density fluctuations and tissue expansion or contraction. Building on Shraiman's area-growth paradigm, we enrich the framework with density-dependent spreading at the pop…

Simulating Organogenesis in COMSOL Multiphysics: Tissue Patterning with Directed Cell Migration
Malte Mederacke, Chengyou Yu, Roman Vetter, Dagmar Iber
https://arxiv.org/abs/2509.08930

Simulating Organogenesis in COMSOL Multiphysics: Tissue Patterning with Directed Cell Migration
We present a COMSOL Multiphysics implementation of a continuum model for directed cell migration, a key mechanism underlying tissue self-organization and morphogenesis. The model is formulated as a partial integro-differential equation (PIDE), combining random motility with non-local, density-dependent guidance cues to capture phenomena such as cell sorting and aggregation. Our framework supports simulations in one, two, and three dimensions, with both zero-flux and periodic boundary conditions…

Hydrodynamic interactions destroy motility-induced phase separation in active suspensions
Tingtao Zhou, John F. Brady
https://arxiv.org/abs/2509.25616 https://

Hydrodynamic interactions destroy motility-induced phase separation in active suspensions
Motility-Induced Phase Separation (MIPS) is a distinctive phenomenon in active matter that arises from its inherent non-equilibrium nature. Despite recent progress in understanding MIPS in dry active systems, it has been debated whether MIPS can be observed in wet systems in which fluid-mediated hydrodynamic interactions (HI) are present. We use theory and large-scale {\it Active Fast Stokesian Dynamics} simulations of the so-called squirmer model to show that collision-induced pusher force dip…

The Morpho-Kinetic Landscape of Macrophage Modes During Wound Healing in Zebrafish
Seol Ah Park, Giulia Lupi, Resul Ozbilgic, Michal Kollar, Aneta A. Ozvat, Mai Nguyen-Chi, Karol Mikula
https://arxiv.org/abs/2507.19314

The Morpho-Kinetic Landscape of Macrophage Modes During Wound Healing in Zebrafish
Macrophages play an essential role in wound healing due to their dynamic nature and functional plasticity, exhibiting highly heterogeneous morpho-kinetic behaviors depending on their activation states. However, quantitative analysis of macrophage behavior in in vivo settings remains limited, largely due to the complexity of their diverse morphologies and motility patterns over time. In this study, we present an analytic workflow to investigate macrophage dynamics in zebrafish. By computing a co…

The role of viral dynamics and infectivity in models of oncolytic virotherapy for tumours with different motility
David Morselli, Federico Frascoli, Marcello Edoardo Delitala
https://arxiv.org/abs/2509.24522

The role of viral dynamics and infectivity in models of oncolytic virotherapy for tumours with different motility
The use of ad-hoc engineered viruses in the fight against tumours is one of the greatest ideas in cancer therapeutics within the last three decades. Together with other strategies such as immunotherapies, nanoparticles and adjunct therapies, the use of viral vectors in clinical trials and in the clinics has been and is still widely studied and pursued. The ability of those vectors to infiltrate and infect tumours represents one of the key attributes that regulates the success of such a strategy…

Defect-Mediated Aggregation and Motility-Induced Phase Separation in Active XY Model
Shun Inoue, Satoshi Yukawa
https://arxiv.org/abs/2507.17108 https://ar…

Defect-Mediated Aggregation and Motility-Induced Phase Separation in Active XY Model
We propose an ``active XY model'' that incorporates key elements of both the classical XY model and the Vicsek model to study the role of topological defects in active matter systems. This model features self-propelled particles with XY spin degrees of freedom on a lattice and introduces a self-propulsion parameter controlling the directional bias of particle motion. Using numerical simulations, we demonstrate that self-propulsion induces motility-induced phase separation (MIPS), where particle…

Replaced article(s) found for cond-mat.stat-mech. https://arxiv.org/list/cond-mat.stat-mech/new
[1/1]:
- Critical Motility-Induced Phase Separation in Three Dimensions is Consistent with Ising Universality
Jiechao Feng, Daniel Evans, Ahmad K. Omar

Replaced article(s) found for cond-mat.soft. https://arxiv.org/list/cond-mat.soft/new
[1/1]:
- Confinement and Activity-Driven Dynamics of Semiflexible Polymers in Motility Assays
Sandip Roy, Abhishek Chaudhuri, Anil Kumar Dasanna

Replaced article(s) found for physics.bio-ph. https://arxiv.org/list/physics.bio-ph/new
[1/1]:
- Contact temporal network during motility induced phase separation
Italo Salas, Francisca Guzm\'an-Lastra, Denisse Past\'en, Ariel Norambuena

Continuum models describing probabilistic motion of tagged agents in exclusion processes
Michael J. Plank, Matthew J. Simpson
https://arxiv.org/abs/2509.25554 https://

Continuum models describing probabilistic motion of tagged agents in exclusion processes
Lattice-based random walk models are widely used to study populations of migrating cells with motility bias and proliferation. Crowding is typically represented by volume exclusion, where each lattice site can be occupied by at most one agent and conflicting moves are aborted. This framework enables simulations that yield both population-level spatiotemporal agent density profiles and individual agent trajectories, comparable to experimental cell-tracking data. Previous continuum models for tag…

A Microfluidic Platform for Actin-Based Membrane Remodeling Reveals the Stabilizing Role of Branched Actin Networks on Lipid Microdomains
Lixin Huang (LAMBE - UMR 8587), Rog\'erio Lopes dos Santos (LAMBE - UMR 8587), Sid Labdi (UEVE, LAMBE - UMR 8587, IUT D'EVRY), Guillaume Lamour (LAMBE - UMR 8587, UEVE), Olek Maciejak (SABNP, LAMBE - UMR 8587), Michel Malo (LAMBE - UMR 8587), John Manzi (LPTMS, PMMH), Martin Lenz (LPTMS, PMMH), Jacques Fattaccioli (IPGG, PASTEUR), Cl\'eme…

A Microfluidic Platform for Actin-Based Membrane Remodeling Reveals the Stabilizing Role of Branched Actin Networks on Lipid Microdomains
Cell shape changes, essential for processes such as motility or division, are controlled by the actomyosin cortex that actively remodels biological membranes. Their mechanisms can be deciphered in___vitro using biomimetic reconstituted systems, such as giant unilamellar vesicles (GUVs) with controlled lipid composition coupled to reconstituted actin networks. These assays allow mimicking cell shape changes in controlled biochemical and biophysical environments. However, studying the dynamics of…

Interfacial Stability in Tensionless Phase-Separated Quorum-Sensing Systems
Zihao Sun, Longfei Li, Fangfu Ye, Mingcheng Yang
https://arxiv.org/abs/2507.15030

Interfacial Stability in Tensionless Phase-Separated Quorum-Sensing Systems
Interfacial phenomena of motility-induced phase separation of active particles challenge our conventional understanding of phase coexistence. Despite the ubiquity of nonmechanical communication couplings among real active particles, most works on active interface have concentrated on active Brownian systems with steric interparticle interactions. Here, we study the interfacial behavior of phase-separated active particles interacting solely via quorum-sensing communications using both theory and…

Large-scale dynamics in visual quorum sensing chiral suspensions
Yuxin Zhou, Qingqing Yin, Shubhadip Nayak, Poulami Bag, Pulak K. Ghosh, Yunyun Li, Fabio Marchesoni
https://arxiv.org/abs/2508.11254

Large-scale dynamics in visual quorum sensing chiral suspensions
Motility induced phase separation is an efficient aggregation mechanism of active matter, yet biological systems exhibit richer organization through communication among constituents. We investigate suspensions of active particles that change chirality when neighbor density within their visual cone exceeds a threshold, a communication based non-reciprocal interaction akin to quorum sensing. Tuning the visual cone triggers programmable transitions: from disorder to phase separation to hyper-unifo…

Likelihood-Based Heterogeneity Inference Reveals Non-Stationary Effects in Biohybrid Cell-Cargo Transport
Jan Albrecht, Lara S. Dautzenberg, Manfred Opper, Carsten Beta, Robert Gro{\ss}mann
https://arxiv.org/abs/2508.12976

Likelihood-Based Heterogeneity Inference Reveals Non-Stationary Effects in Biohybrid Cell-Cargo Transport
Variability of motility behavior in populations of microbiological agents is an ubiquitous phenomenon even in the case of genetically identical cells. Accordingly, passive objects introduced into such biological systems and driven by them will also exhibit heterogeneous motion patterns. Here, we study a biohybrid system of passive beads driven by active ameboid cells and use a likelihood approach to estimate the heterogeneity of the bead dynamics from their discretely sampled trajectories. We s…