Tootfinder

Isomorphic Labs, a Google DeepMind spinoff, unveils IsoDDE, a drug design system it says surpasses AlphaFold 3 in predicting biomolecular structures (Isomorphic Labs)
https://www.isomorphiclabs.com/articles/the-isomorphic-labs-drug-design…

The Isomorphic Labs Drug Design Engine unlocks a new frontier beyond AlphaFold - Isomorphic Labs
Today, we are excited to share an update on our progress towards a new frontier of drug design. We have unlocked a new paradigm of predictive accuracy in understanding our biomolecular world, allowing us to rationally design new medicines on a computer with unprecedented understanding and precision.

I spent quite a few evening hours this past week modeling the production Morserino M32 Pocket case in FreeCAD. The original had basically been forked in a mesh editor, which made it hard to work from. Hans (of QRP Labs) kindly released his STLs, which made this work easier and the resulting objects better.
If you want a different color, or different plastic, or to make a modification to the design, you…

#Tanzania crackdown on planned protest leaves streets deserted
https://www.bbc.com/news/articles/cx2e3j819eqo

Tanzania crackdown on planned protest leaves streets deserted
There is a large police presence in major cities and the authorities have encouraged people to stay home.

The London Warriors: The amateur team that changes lives and has produced a Super Bowl winner https://www.nytimes.com/athletic/7032803/2026/02/09/london-warriors-aden-durde-super-bowl-seattle-seahawks/

So this is percolating and the results so far are not surprising.
I'd vote NO, for the following reasons:
- oil demand continues to decline and risk is high we'll end up with an expensive underutilized pipeline. Therefore high risk we'll end up subsidizing any private entity that builds this thing.
- why would we invest public dollars to support infrastructure for a product where 75% of the profit leaves Canada? There has to be a net benefit, beyond steel sales and jobs, for this project to be considered.
- Indigenous land rights must be respected. They will be left with the rusting pipeline decades in the future, and it's impact on the land.
- the B.C. government must also have a final vote as they have to give up land and provide support.
- we don't need additional oil tankers on our west coast.
- and most importantly, with this MOU, Canada pretty much declared we aren't serious about protecting the environment or fighting climate change. We're oil whores. Harsh but....
#CanPoli #ClimateAction

ICE Out for Good
https://www.mobilize.us/indivisible/event/883895/

ICE Out For Good | Died In Detention/During Raids Protest · Indivisible
36 lives have been lost in the past year alone: 5 during ICE Raids and 31 or more while detained. Wednesday, January 7th, we all saw Renee Good killed by Immigration and Customs Enforcement (ICE) in Minneapolis, Minnesota. They had killed another Silverio Gonzalez in Chicago, but without the benefit of a video. These killings are a part of a broader pattern of unchecked violence, impunity, and abuse carried out by federal immigration enforcement agencies against members of our communities. …

Yes, Switzerland🇨🇭 loves ⛰️ peaks. But when it comes to solar power, it's okay to take a little bit off the top.
From 2026 onwards, (new) solar power installations must limit their peak capacity to 70%. This only slightly reduces production, but it does reduce the simultaneous load on the grid.
https://www.…

Neue Regeln bei der Einspeisung von Solarstrom
Die Energiewende ist in vollem Gang. Solaranlagen boomen und liefern immer mehr erneuerbaren Strom. Eine positive Entwicklung, die auf unsere Energie- und Klimaziele einzahlt. Doch wenn an sonnigen Mittagen alle Solaranlagen gleichzeitig Strom einspeisen, entstehen Leistungsspitzen, die das Stromnetz an seine Grenzen bringen. Es herrscht sozusagen Stau im Netz.

Michael Burry, Anthropic co-founder Jack Clark, and Dwarkesh Patel on the future of AI, whether AI tools improve productivity, job losses due to AI, and more (The Substack Post)
https://post.substack.com/p/the-ai-revolution-is-here-will-the

The AI revolution is here. Will the economy survive the transition?
The man who predicted the 2008 crash, Anthropic’s co-founder, and a leading AI podcaster jump into a Google doc to debate the future of AI—and, possibly, our lives

@… Ich muss dir was zeigen: https://mastodon.art/@Dinosalabs/116040669912930515

Dinosa Labs 🦕🧶 Amigurumis (@Dinosalabs@mastodon.art)
Attached: 2 images Vine a presumiros la Abubilla que diseñé ♥ Mirad cómo se queda de pie y estable sobre sus pataticas jijiji Tenéis mas fotos aquí: https://www.dinosalabs.es/producto/abubilla-upupa-epops/ #abubilla #upupaepops #puput #crochet #ganchillo #aves #MastoArt

A software engineer explains AI fatigue, compounded by a FOMO treadmill of using labs' latest tools, thinking atrophy, and more, alongside boosted productivity (Siddhant Khare)
https://siddhantkhare.com/writing/ai-fatigue-is-real

AI fatigue is real and nobody talks about it | Siddhant Khare
You're using AI to be more productive. So why are you more exhausted than ever? The paradox every engineer needs to confront.