Tootfinder

Google DeepMind researchers unveil AlphaGenome, an AI model trained on molecular data to predict 11 different genomic processes, such as gene splicing (Carl Zimmer/New York Times)
https://www.nytimes.com/2026/01/28/science/alphagenome-ai-deepmind-genetics.htm…

With AlphaGenome, Researchers Are Using A.I. to Decode the Human Blueprint
AlphaGenome is a leap forward in the ability to study the human blueprint. But the fine workings of our DNA are still largely a mystery.

Good Morning #Canada
This has been quite the roller-coaster year for my wife and I. If there was one thing that I would be thankful for it would be our much maligned #Healthcare system. Through early testing, in April 2025, both our daughters were diagnosed with a genetic defect that significantly increases risk of cancer. Breast cancer was found in our oldest daughter and her treatment included surgery, chemo, and radiation. The prognosis for a longer life is now excellent. The youngest is facing potential preventative surgery to reduce her risk. After diagnosis the medical response was immediate and both daughters have numerous stories about caring individuals that have provided treatment, counseling, and empathy.
One man had a huge impact on Canada’s status as an important centre for genetics research - Dr. Lou Siminovitch. Here is his story about how he helped establish 4 different research organizations in Toronto.
#CanadaIsAwesome #CanadianHeroes
https://www.cbc.ca/news/canada/toronto/dr-lou-siminovitch-the-force-behind-early-genetics-research-in-canada-dies-at-age-100-1.5981522

Jeanty, Mayer, Tucker, Laulu, Rogers, Vance, Glaze Postgame Media https://www.raiders.com/video/jeanty-mayer-tucker-laulu-rogers-vance-glaze-postgame-media-week-17

“How can one mutation cause such different effects?”
Pera explained. “It comes down to genetic background.
Each strain has a unique genetic makeup that can either protect against or magnify the impact of that mutation.”
To confirm these findings in living organisms, Pera introduced the same mutations into live mice from the same eight strains.
Remarkably, the neurons in the brains of these mice phenotypically matched what he had seen in the petri dish,
providin…

What stem cells tell us about autism and other developmental brain disorders
By pairing stem cell technology with genetic diversity, JAX researchers uncover why identical mutations can lead to severe disease in some—and no symptoms in others.

mist: MIST protein interaction database (2020)
The Molecular Interaction Search Tool (MIST) is a comprehensive resource of molecular interactions, assembled from severla primary sources. MIST currently supports several species, including:.
This network has 27105 nodes and 334495 edges.
Tags: Biological, Protein interactions, Unweighted

Memo: the BBC presents plans to save £100M by shrinking its workforce to invest in digital resources and content, potentially affecting jobs in legal and more (Jake Kanter/Deadline)
https://deadline.com/2025/11/bbc-100m-savings-plan-project-ada-1236628458/

BBC Confirms Plans To Save $130M By Shrinking & Rethinking Workforce
The BBC has confirmed plans to save £100M by radically reimagining its workforce to compete with tech giants. The plan is known as Project Ada.

Renner's 2026 NFL mock draft 5.0: Giants trade No. 1 pick as Rams plan for life after Matthew Stafford

https://www.cbssports.com/nfl/draft/news/2026-nfl-mock-dr…

Researchers detail popEVE, an AI model to predict the disease-causing potential of unknown human genetic mutations, and says it beats Google's AlphaMissense (Michael Peel/Financial Times)
https://www.ft.com/content/bc49e334-776b-41d0-a9be-fb0c29c54853

The offices at John Quackenbush’s lab at the Harvard T.H. Chan School of Public Health
were once full of postdoctoral fellows, graduate students, and interns.
Young scientists here worked on some of the most cutting-edge computational biology research in the world,
driving new discoveries and the creation of widely used big data tools, including one the National Cancer Institute named among the most important advances of 2024.
Today, the offices are rows of empty comp…

His lab was humming with discovery. After one year under Trump, it’s almost silent
John Quackenbush built a lab that is at the forefront of human genetics research and bioinformatics. Trump administration cuts have put it in danger of collapse.

mist: MIST protein interaction database (2020)
The Molecular Interaction Search Tool (MIST) is a comprehensive resource of molecular interactions, assembled from severla primary sources. MIST currently supports several species, including:.
This network has 4209 nodes and 13882 edges.
Tags: Biological, Protein interactions, Unweighted