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Information-Theoretical Measures for Developmental Cell-Fate Proportioning Processes
Michael A. Ramirez-Sierra, Thomas R. Sokolowski
https://arxiv.org/abs/2505.23659

Information-Theoretical Measures for Developmental Cell-Fate Proportioning Processes
Self-organization is a fundamental process of complex biological systems, particularly during the early stages of development. In the mammalian embryo, blastocyst formation exemplifies a self-organized system, involving the correct spatio-temporal segregation of three distinct cell fates: trophectoderm (TE), epiblast (EPI), and primitive endoderm (PRE). Despite the significance of this class of processes, quantifying the information content of self-organizing patterning systems remains challeng…

Consideraciones para una formulaci\'on Termodin\'amica Neo-Gibbsiana aplicada a sistemas sociales
Victor Alcides Guzm\'an Rodr\'iguez, Esneiber Hibraim Solano Herrera
https://arxiv.org/abs/2506.01794

Consideraciones para una formulación Termodinámica Neo-Gibbsiana aplicada a sistemas sociales
This work proposes a first approach towards a neo-Gibbsian thermodynamic theory for social systems, grounded in quantifiable economic and cultural parameters, while deliberately avoiding direct analogies with classical thermodynamic equations of state. Building on previous thermodynamic approaches to economic modeling, we introduce a conceptual basis for defining intensive variables capable of characterizing equilibrium states and evolutionary dynamics in societies. Particular attention is give…

This https://arxiv.org/abs/2305.14653 has been replaced.
initial toot: https://mastoxiv.page/@arX…

Conceptualizing educational opportunity hoarding: the emergence of hoarding without hoarders
Social scientists increasingly use the concept of opportunity hoarding to explain the formation of Black-White educational inequalities. However, this concept is often loosely defined, leading to varied interpretations of the inequality-producing mechanisms it captures. To bring clarity to this valuable sociological concept, this theoretical paper, informed by the concept's original definition and existing empirical research, proposes a more precise definition of opportunity hoarding and formal…

Initial Luminally Deposited FGF4 Critically Influences Blastocyst Patterning
Michael A. Ramirez-Sierra, Thomas R. Sokolowski
https://arxiv.org/abs/2505.23650

Initial Luminally Deposited FGF4 Critically Influences Blastocyst Patterning
Luminogenesis, the formation of a fluid-filled cavity (lumen), is an essential process in early mammalian embryonic development, coinciding with the second cell-fate decision that differentiates the inner-cell-mass (ICM) into epiblast (EPI) and primitive endoderm (PRE) tissues. Based on experiments, the blastocyst lumen is hypothesized to influence EPI-PRE tissue specification, but its particular functional role remains theoretically underexplored. In this study, we extended our stochastic ICM …