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Conditional diffusion models for guided anomaly detection in brain images using fluid-driven anomaly randomization
Ana Lawry Aguila, Peirong Liu, Oula Puonti, Juan Eugenio Iglesias
https://arxiv.org/abs/2506.10233

Conditional diffusion models for guided anomaly detection in brain images using fluid-driven anomaly randomization
Supervised machine learning has enabled accurate pathology detection in brain MRI, but requires training data from diseased subjects that may not be readily available in some scenarios, for example, in the case of rare diseases. Reconstruction-based unsupervised anomaly detection, in particular using diffusion models, has gained popularity in the medical field as it allows for training on healthy images alone, eliminating the need for large disease-specific cohorts. These methods assume that a …

Beyond the LUMIR challenge: The pathway to foundational registration models
Junyu Chen, Shuwen Wei, Joel Honkamaa, Pekka Marttinen, Hang Zhang, Min Liu, Yichao Zhou, Zuopeng Tan, Zhuoyuan Wang, Yi Wang, Hongchao Zhou, Shunbo Hu, Yi Zhang, Qian Tao, Lukas F\"orner, Thomas Wendler, Bailiang Jian, Benedikt Wiestler, Tim Hable, Jin Kim, Dan Ruan, Frederic Madesta, Thilo Sentker, Wiebke Heyer, Lianrui Zuo, Yuwei Dai, Jing Wu, Jerry L. Prince, Harrison Bai, Yong Du, Yihao Liu, Alessa He…

Beyond the LUMIR challenge: The pathway to foundational registration models
Medical image challenges have played a transformative role in advancing the field, catalyzing algorithmic innovation and establishing new performance standards across diverse clinical applications. Image registration, a foundational task in neuroimaging pipelines, has similarly benefited from the Learn2Reg initiative. Building on this foundation, we introduce the Large-scale Unsupervised Brain MRI Image Registration (LUMIR) challenge, a next-generation benchmark designed to assess and advance u…