Tootfinder

Opt-in global Mastodon full text search. Join the index!

@lpryszcz@genomic.social
2026-08-24 04:27:13

Individualized mRNA vaccines evoke durable T cell immunity in adjuvant TNBC
#RNA #vaccine #moderna

Individualized mRNA vaccines evoke durable T cell immunity in adjuvant TNBC - Nature
In a phase 1 trial, personalized mRNA vaccines tailored to individual tumour mutations in triple-negative breast cancer induced robust, long-lasting T cell responses and improved prognosis.

@lpryszcz@genomic.social
2026-08-10 07:05:01

Quantitative #RNA #modification mapping by #mass #spectrometry with isobaric tags and nucleobase fragment…

Quantitative RNA modification mapping by mass spectrometry with isobaric tags and nucleobase fragment analysis - Nature Communications
The locations and levels of RNA modifications are key to understanding their biological functions. Here, the authors develop proteomics-style, RNA-specific isobaric tandem mass tags for quantitative RNA modification mapping by mass spectrometry, revealing condition-dependent changes and interdependencies among modification pathways.