Tootfinder

England's Esme Morgan on making America home and why she loves the Jacksonville Jaguars https://www.nytimes.com/athletic/6715854/2025/10/17/esme-morgan-washington-spirit-nwsl-jacksonville-jaguars-nfl/

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👍✅ Runtimes supporting CommonJS and ESM
👎❌ Modules dual publishing both CommonJS and ESM

Esmeralda 7 Solar Project Has Been Canceled, BLM Says (Jael Holzman/Heatmap News)
https://heatmap.news/sparks/esmeralda-7-canceled-nevada-solar
http://www.memeorandum.com/251010/p2#a251010p2

Deno both supports and absolutely does not support CommonJS 😅
1️⃣ https://docs.deno.com/examples/cjs_to_esm_tutorial/
2️⃣ https://…

Draft plans: EU is pushing for market regulator ESMA to get supervision and authorization powers over crypto firms, shifting oversight from national regulators (Bloomberg)
https://www.bloomberg.com/news/articles/2025-11-14/eu…

InstructPLM-mu: 1-Hour Fine-Tuning of ESM2 Beats ESM3 in Protein Mutation Predictions
Junde Xu, Yapin Shi, Lijun Lang, Taoyong Cui, Zhiming Zhang, Guangyong Chen, Jiezhong Qiu, Pheng-Ann Heng
https://arxiv.org/abs/2510.03370

InstructPLM-mu: 1-Hour Fine-Tuning of ESM2 Beats ESM3 in Protein Mutation Predictions
Multimodal protein language models deliver strong performance on mutation-effect prediction, but training such models from scratch demands substantial computational resources. In this paper, we propose a fine-tuning framework called InstructPLM-mu and try to answer a question: \textit{Can multimodal fine-tuning of a pretrained, sequence-only protein language model match the performance of models trained end-to-end? } Surprisingly, our experiments show that fine-tuning ESM2 with structural input…

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https://open.spotify.com/track/7FNDGt5eSMFn7bgpZ8mm0l
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