Tootfinder

🧬 Golden Gate method enables fully-synthetic engineering of therapeutically relevant bacteriophages
#molbio

Golden Gate method enables fully-synthetic engineering of therapeutically relevant bacteriophages
Bacteriophages have been used therapeutically to treat infectious bacterial diseases for over a century. As antibiotic-resistant infections increasingly threaten public health, interest in bacteriophages as therapeutics has seen a resurgence. However, the field remains largely limited to naturally occurring strains, as laborious strain engineering techniques have limited the pace of discovery and the creation of tailored therapeutic strains.