Tootfinder

"When I got into the film business, my aim was to adopt a positive persona, of a guy who fights against injustice. And it saved me, because my acting was atrocious to say the least!"
—Chuck Norris
#acting #coaching

OpenAI partners with six Indian education institutions, including IIT Delhi, IIM Ahmedabad, and AIIMS New Delhi, to provide ChatGPT Edu access to 100K students (Jagmeet Singh/TechCrunch)
https://techcrunch.com/2026/02/18/openai-pushes…

OpenAI pushes into higher education as India seeks to scale AI skills | TechCrunch
OpenAI says its India education partnerships aim to reach more than 100,000 students, faculty and staff over the next year.

Americas flyways atlas maps the routes of 89 at-risk migratory bird species https://news.mongabay.com/2026/04/americas-flyways-atlas-maps-the-routes-of-89-at-risk-migratory-bird-species/

Americas flyways atlas maps the routes of 89 at-risk migratory bird species
Announced at the end of March, the “Atlas for the Americas Flyways” website tracks high concentrations of migratory bird species at risk of major population declines along their routes throughout the Americas. This new United Nations-backed tool identifies heavily trafficked breeding grounds, migratory stopover locations and wintering areas, with the aim of providing policymakers and […]

End fracking and LNG expansion
Beyond a petition — become part of a community for change.
The B.C. government needs to end fracking and liquified natural gas (LNG) expansion now. We know that consistent, concerted pressure from as many people as possible moves decision-makers, and our aim is to make it easy for tens of thousands of people to raise their voices together.
Sign the petition and join the collective people-powered movement to end fracking and LNG in B.C.

End fracking and LNG expansion | Wilderness Committee
Sign our petition and call on B.C. to protect communities from climate disasters by ending fracking in the province!

RE: https://mastodon.social/@sarada9669/116084573965927023
The aim of genocide is to erase a people.
The UK is complicit in this one in more ways than one.

"When I got into the film business, my aim was to adopt a positive persona, of a guy who fights against injustice. And it saved me, because my acting was atrocious to say the least!"
—Chuck Norris
#acting #coaching

"When I got into the film business, my aim was to adopt a positive persona, of a guy who fights against injustice. And it saved me, because my acting was atrocious to say the least!"
—Chuck Norris
#acting #coaching

In einer kleinen Studie wurden #Mikroplastik-Partikel in den Plazenten von drei trächtigen #Katzen und in Föten von zwei Tieren nachgewiesen.
Insgesamt fanden Forschende 19 verschiedene #Kunststoffarten

Detection of microplastics in the feline placenta and fetus
The present study aimed to detect microplastics in feline placentas and fetuses in the early stage of pregnancy. For this study, 8 pregnant queens were evaluated. A standardized protocol for the digestion of biological matter was used, as well as a plastic-free approach for sample collection and manipulation. Microplastics were investigated by means of Raman spectroscopy, with the aim of identifying their composition. Four of eight animals were contaminated, with a total of 19 microplastics det…

With the eight week improv course ending last week, I timed it well to start a new group with a new set of eight sessions this week.
The Free Association seem more serious than Hoopla. They have 50% longer classes for a start. Three hours rather than two.
More instruction and notes rather than just positive encouragement. Clearer aim even from the early levels. More like a classroom than a playground.
First couple of sets of eight at Hoopla are just aimed at getting you to lose your decorum and allow yourself to be free and spontaneous. All really short form games, lightning rounds. Parlor games rather than theater.
But the Free Association's aim from the start is to get you building scenes and then stories. Their first set of lessons is titled "intro to long form". This one "Scene work".
Not so much the one minute parlor games, more focus on acting and characters and drama.
In vague terms at early stages that is. I mean, they have more in common than different. Plenty of short games in warm-up at FA and I just finished a whole set on drama and story with Hoopla.
Three hours is pretty long though. Starts half an hour earlier, ends half an hour later. Good thing it's also much much closer for me. Ten minute walk instead of 40 minutes on the bus.
We did lots and lots of first-scene head-to-head, mostly concentrating on trying to get specific. Check that after two minutes the audience knows where you are and who you are and how you know each other and what you're doing and none of the players are unsure either. Make it all specific as soon as possible, ambiguity is the enemy.
And everyone got that and exercised it pretty much flawlessly right away. So good group.
#theFreeAssociation #improv #london

Pete Carroll shoulders blame for Geno Smith's struggles, takes aim at Raiders' front office after firing

https://www.cbssports.com/nfl/news/pete-carroll-geno-smith-raiders-firin…

Norway's Consumer Council takes aim at enshittification
#norway

A classified Israeli military database ... indicated that of more than 53,000 deaths recorded in Gaza, named Hamas and Islamic Jihad fighters accounted for roughly 17%. That suggests the rest, 83%, were civilians. These are not the statistics of a war fought with precision, this is a war where imprecision is the aim.
When reported verification times for AI-assisted targets are measured in seconds, ... the consequences are written in rows of small coffins.

Beehiiv introduces Podcasts, letting creators host, distribute, and monetize podcasts directly on the platform, and plans to dynamically serve ads in podcasts (Aisha Malik/TechCrunch)
https://techcrunch.com/2026/04/02/beehiiv-expand…

Exclusive: Beehiiv expands into podcasting, taking aim at Patreon | TechCrunch
One way Beehiiv is convincing creators to switch from rivals like Substack and Patreon is by not taking a cut of revenue.

NFL Raiders, WNBA Aces presidents aim for success both on, off field of play https://www.reviewjournal.com/sports/raiders/nfl-raiders-wnba-aces-presidents-aim-for-success-both-on-off-field-of-play-3614337/<…

'We aim to kill 50,000 Russians a month,' Ukraine's new defense minister says: https://benborges.xyz/2026/01/20/we-aim-to-kill-russians.html

We speak with economist
Michael Hudson,
who details how Trump opted to attack Iran despite progress at indirect U.S.-Iran negotiations.
“The whole reason that America has attacked Iran has nothing to do with its getting an atom bomb,”
but instead the aim was U.S. control of oil, says Hudson.
The Trump administration may have been after the ability to “turn off the power” to countries that don’t follow U.S. foreign policy, he says

A War for Oil: Economist Michael Hudson on U.S. Quest to Control the World’s Oil Trade
We speak with economist Michael Hudson, who details how President Trump opted to attack Iran despite progress at indirect U.S.-Iran negotiations. “The whole reason that America has attacked Iran has nothing to do with its getting an atom bomb,” but instead the aim was U.S. control of oil, says Hudson. The Trump administration may have been after the ability to “turn off the power” to countries that don’t follow U.S. foreign policy, he says.

Super Mario World: completed!
I didn't get lost again, but that was largely because the game's designers had finished messing around with the world map and everything was fairly linear from that point. I did find a couple of extra exits on Chocolate Island, but maintaining my aim of ignoring the red blinking markers and just pushing through to the end, I finished off Wendy and progressed through the shipwreck down to Bowser's hidden valley, previously submerged beneath…

The German Research Association (@…) has established binding framework conditions for the use of AI. The aim is to ensure the legally compliant and transparent use of AI, taking technological developments into account while maintaining scientific integrity:

Artificial Intelligence in the Review Process

Your personal data might set your grocery prices. States aim to crack down. - Route Fifty
https://www.route-fifty.com/digital-government/2026/03/your-personal-data-might-set-your-grocery-prices-states-aim-crack-down/412435/

🇺🇦 #NowPlaying on KEXP's #StreetSounds
The Neighborhood Kids:
🎵 THEY AIM AT US
#TheNeighborhoodKids
https://theneighborhoodkids.bandcamp.com/track/they-aim-at-us-ft-indigenous-cats
https://open.spotify.com/track/11OzFg3wQmltnkvX1mzM9w

"Bilby boom: breeding trial to reintroduce species to Mallee Cliffs national park shows signs of success"
#Animals #Conservation

Federal Vaccine Advisers Take Aim at Covid Shots (Apoorva Mandavilli/New York Times)
https://www.nytimes.com/2026/02/06/health/vaccines-covid-acip-malone-kennedy.html
http://www.memeorandum.com/260206/p116#a260206p116

"The Zero Emissions Truck and Van grants and the Depot Charging Scheme (DCS) aim to tackle two of the biggest barriers to businesses making the switch - upfront costs and access to charging."
£1 billion (up to 40% of the vehicle cost) £170 million (up to 70% of depot charging infrastructure cost)

£1 billion to cut costs for businesses, drive growth and clean up UK roads
The Zero Emissions Truck and Van grants and the Depot Charging Scheme aim to help businesses make the switch to electric vans and trucks.

Satellite executives, investors, and researchers say Elon Musk's aim to launch space data centers by around 2029 is highly ambitious, but the idea is plausible (Tim Bradshaw/Financial Times)
https://www.ft.com/content/a5cf86ec-47cb-448f-b4a3-56ca6390ad8e

Publicis acquires content intelligence firm AdgeAi, to identify the most effective creative elements of ad campaigns and to improve content strategy and ROI (Steve McClellan/MediaPost)
https://www.mediapost.com/publications/art

Publicis Acquires Content Optimizer AdgeAi
Adge's AI-powered platform optimizes creative and video performance by analyzing engagement and conversion data. The aim is to identify the most effective creative elements to help develop content strategy and improve campaign ROI.

Automatically describe data and models as text using the {report} package. #rstats

"When I got into the film business, my aim was to adopt a positive persona, of a guy who fights against injustice. And it saved me, because my acting was atrocious to say the least!"
—Chuck Norris
#acting #coaching

RE: https://mastodon.scot/@kim_harding/116034323343458077
Great news for the environment. Keep it up, folks. Zero is a fair value; let’s aim for that and see how close we can get ;)

🇺🇦 #NowPlaying on #BBC6Music's #TheBBCIntroducingMixtape
Aimée Fatale:
🎵 The Way It Goes
#AiméeFatale
https://open.spotify.com/track/5vD3lRPL9abnIRFwePhDVR

"Sharp-tongued viewers first took aim at the single, timed nibble McDonald's CEO Kempczinski took from the XXL burger during the entire 81-second video."
Competitors Burger King and Wendy's pounced,
issuing snarky videos of their own execs happily chomping on their burgers.

McDonald’s CEO Wanted to Sell a Burger. Instead, He Sparked a Viral Lesson in Executive Self‑Awareness
The failure of one CEO’s video, paired with a rival’s sparkling success, provides attention-seeking bosses a tough reminder.

"The aim of the Ukraine government, the EU, the US government, the multilateral agencies and the American financial institutions now in charge of raising funds and allocating them for reconstruction is to restore the Ukrainian economy as a form of special economic zone, with public money to cover any potential losses for private capital."
Ukraine- Russia four years on – Michael Roberts Blog

Ukraine- Russia four years on
Today marks the end of the fourth year of the Ukraine-Russia war. After four years, Russia’s invasion of Ukraine has caused staggering damage to Ukraine’s people and economy. There are wildly varyi…

Sources: Sequoia's Ravi Gupta and ex-Meta CRO John Hegeman seek to raise $1B for a holding company to acquire at least one firm and infuse it with new tech (Bloomberg)
https://www.bloomberg.com/news/articles/20…

Raiders aim to hire Klint Kubiak: Seahawks OC expected to head to Las Vegas, per reports

https://www.cbssports.com/nfl/news/raiders-coach-klint-kubiak-seahawks-super-bowl/<…

"Digitizing Intangible Culture, Identity and Memory: Eurotales, a Museum of the Voices of Europe"
#language

Global oil supply hit by US-Israeli war against Iran. Oil and gasoline prices up. And... of course some parties in Dutch parliament now ask for (tax) subsidies to keep demand high.
President of Central bank DNB: Don't do this! Aim financial support at lower incomes.
https://nos.nl/l/2607642

Druk op kabinet neemt toe, Kamer wil maatregelen tegen hoge prijzen
Morgen is er een debat over de economische gevolgen van de oorlog in het Midden-Oosten.

1 Thing the Raiders' Future Will be Built On https://www.si.com/nfl/raiders/onsi/1-thing-las-vegas-future-will-be-built-on

I donated to Develop Africa to support students in Sierra Leone.
https://www.developafrica.org/about-develop-africa
"we provide education, child sponsorship, leadership development, workforce empowerment, and more to poverty-stricken African communities. We aid in br…

Whee. My olleeWatch just entered shipping. So excited
#casio #casiowatch

Ollee Watch
Ollee Watch is a smartwatch modification for classic digital watches, primarily the Casio F91W and A158W. We aim to provide a low maintenance smartwatch experience, minimize the noise of the modern world with a simple, functional and highly customizable watch platform.

The fact that Anthony has been looking for work for an extended period is an indictment of the whole IT employment scam. @… https://tilde.zone/@sirwumpus/1159397382639…

[OT, LinkedIn] The Napsterization of AI — and why it hits different https://www.linkedin.com/pulse/napsterization-ai-why-hits-different-brian-malone-yebqe On how Chinese AI labs aim to undercut U.S. tech giants by flooding the market with cheaper, …

The Napsterization of AI — and Why It Hits Different
Or: Why is this Nigerian prince asking me to help him combine statistical rigor with deep domain knowledge to design explainable foundation models for tabular data? Yesterday, Anthropic published something worth reading carefully: they caught three Chinese AI labs — DeepSeek, Moonshot, and MiniMax —

Years ago, I developed a #Kotlin #GUI to help me rename my files in batch. Last week, I was surprised to see that it didn’t work to rename a network volume, though it had in the past. In this post, I aim to describe the issue and its solution.

"Rubbish and recycling in England: what’s changing and why it matters"
#UK #UnitedKingdom #Recycling

Members of the American Indian Movement (AIM) and of the Many Shields Warrior Society (an Indigenous community security group) have been patrolling the streets of Minneapolis’s Phillips neighborhood since the start of the occupation, and they do not plan to stop.
“We all have a place. My place is to make sure people are fed and get a cup of coffee,” Rice said.
As is the case with many Minneapolis residents who do not imagine themselves as demonstrators — much less radicals — gett…

Indigenous-Led Collectives Are Keeping Minnesotan Communities Safe From ICE
Members of the American Indian Movement and the Many Shields Warrior Society are patrolling the streets of Minneapolis.

Will The UK Finally Ban Boiling Crabs Alive For Food? Here’s What You Need To Know #AnimalRights

Will The UK Finally Ban Boiling Crabs Alive For Food? Here’s What You Need To Know
The UK government’s new animal welfare strategy takes aim at the live boiling of crabs and other decapods, but will there really be a ban?

Temporary exemptions for electric vehicles from traffic charges, which aim to reduce traffic, are not a sustainable strategy. Logically, this will also come to an end in Rome, although the cost of a permit will still be attractive at half that for cars with combustion engines.
https://www.

Rome to introduce ZTL access charges for EVs from July - electrive.com
From 1 July 2026, electric vehicle drivers in Rome will no longer enjoy largely free access to the city’s restricted traffic zone (ZTL – Zona a Traffico

Hackers and Trolls Target Wave of ICE Spotting Apps https://www.404media.co/hackers-and-trolls-target-wave-of-ice-spotting-apps/

One Extraordinary Photo: AP photographer uses infrared technology as surveillance tool | AP News https://apnews.com/article/2025-invisible-infrared-surveillance-technology-extraordinary-photo

One Extraordinary Photo: AP photographer uses infrared technology as surveillance tool
The aim was to show how powerful surveillance technology such as face recognition appears when used on individuals controlled by state agencies.

"When I got into the film business, my aim was to adopt a positive persona, of a guy who fights against injustice. And it saved me, because my acting was atrocious to say the least!"
—Chuck Norris
#acting #coaching

Raiders hire Klint Kubiak: Seahawks OC lands Las Vegas job after Super Bowl win

https://www.cbssports.com/nfl/news/raiders-coach-klint-kubiak-seahawks-super-bowl/

⚰️ Fentanyl or phony? Machine learning algorithm learns to pick out opioid signatures
#sensors

Fentanyl or phony? Machine learning algorithm learns to pick out opioid signatures
New forms of fentanyl are created every day. For law enforcement, that poses a challenge: How do you identify a chemical you've never seen before? Researchers at Lawrence Livermore National Laboratory (LLNL) aim to answer that question with a machine learning model that can distinguish opioids from other chemicals with an accuracy over 95% in a laboratory setting.

Maxx Crosby Faces New Cowboys Trade Speculation https://heavy.com/sports/nfl/las-vegas-raiders/maxx-crosby-faces-new-cowboys-trade-speculation/

Gorsuch takes aim at Supreme Court’s Trump prejudice — and calls out Congress’ dysfunction - Alternet.org
https://www.alternet.org/supreme-court-trump-2675291231/

Perfect Cowboys Draft Target Emerges After Lighting Up Miami Pro Day https://www.si.com/nfl/cowboys/onsi/draft/perfect-dallas-cowboys-nfl-draft-target-miami-hurricanes-pro-day

The paragraph
"Amateurs and cranks aim higher, and are currently producing large documents which purport to contain breakthrough results, but which do not survive 5 minutes of expert scrutiny. I continually find it surprising that a non-expert can genuinely believe that they might contribute to research mathematics using only the tools which the experts also have access to. ..."
is taking the words right out of my mouth!!
https://xenaproject.wordpress.com/2026/02/09/accelerating-mathematics/

Asia's smaller chip companies are joining their bigger peers in hiking prices as robust AI demand fuels capex, projected to rise 25% YoY to over $136B in 2026 (Nikkei Asia)
https://asia.nikkei.com/business/techn

Chip price hikes spread as Asia's chipmakers plan record $136bn spending
Smaller suppliers aim to lift rates for first time in years on supply crunch

Barry Jones had been thinking about climate change since the 1960s.
But as he would discover, foresight rarely aligns with political incentives.
“I would say to Bob Hawke: ‘Look, we’ve got to take the issue of climate change seriously’,” he recalls.
“And he’d say, ‘but when’s the impact going to be seen at its worst?’
“And you think, well, it might be another 25 years
and he’d reply:
‘Well, you come back to me sometime later, before the 25 years is up, …

The man who knew too much: Barry Jones on Albo, Putin and the end of the line
At 93, the Labor legend and former science minister is eyeing the “exit ramp”. But he isn’t going quietly, taking aim at Anthony Albanese’s lack of courage on reform and a political system that has lost its way.

In today's dynamic world, adaptability is crucial. A flexible online business using a simple, step-by-step system can transform your life. My aim is to empower entrepreneurs with the support and mentorship needed to make SUCCESS achievable and effortless. Let's turn ambitions into reality! 💼✨ #EntrepreneurshipExpert

"When I got into the film business, my aim was to adopt a positive persona, of a guy who fights against injustice. And it saved me, because my acting was atrocious to say the least!"
—Chuck Norris
#acting #coaching

Memo: another CBS News producer leaves, after 46 years, and says, "We've been told to aim our reporting at a particular part of the political spectrum" (Jeremy Barr/The Guardian)
https://www.theguardian.com/media/2026/feb/27/cbs-news-…

New protest art on National Mall takes aim at Trump and Epstein files (Joe Heim/Washington Post)
https://www.washingtonpost.com/dc-md-va/2026/01/19/trump-epstein-birthday-card-mall/
http://www.memeorandum.com/260120/p57#a260120p57

NFL news roundup: Ravens aim to extend Lamar Jackson, offer C Tyler Linderbaum 'market-setting' contract https://www.nfl.com/news/nfl-news-roundup-latest-league-updates-from-tuesday-feb-24

"'The plastic divide'—how carrier bag bans impact the poorest communities"
#Plastic #Pastics #PlasticBags

'The plastic divide'—how carrier bag bans impact the poorest communities
A new study from The University of Manchester has shed light on an unexpected consequence of plastic bag bans in East Africa, and why well-intentioned environmental laws may actually be making life harder for the people they aim to protect.

Ultrahomogeneity and $\omega$-categoricity of monounary algebras
Thomas Quinn-Gregson
https://arxiv.org/abs/2603.26616 https://arxiv.org/pdf/2603.26616 https://arxiv.org/html/2603.26616
arXiv:2603.26616v1 Announce Type: new
Abstract: Ultrahomogeneity and $\omega$-categoricity are two central concepts arising from model theory, with strong connections with oligomorphic permutation groups and quantifier elimination. In particular, both are conditions on the automorphism group of a structure.
The aim of this paper is to describe both the $\omega$-categorical monounary algebras and the ultrahomogeneous monounary algebras of arbitrary cardinalities. We show that a monounary algebra is $\omega$-categorical [ultrahomogeneous] if and only if every element has finite height and Aut$(\mathcal{A})$ has only finitely many 1-orbits [$\mathcal{A}$ is 1-ultrahomogeneous]. Our classification of ultrahomogeneous monounary algebras is then viewed in the context of previously studied variants of ultrahomogeneity, including (partial)-homogeneity and transitivity.
toXiv_bot_toot

Anthropic plans a 30-second ad during the Super Bowl parodying the prospect of intrusive ads in AI conversations, and will also air a 60-second pre-game ad (Suzanne Vranica/Wall Street Journal)
https://www.wsj.com/bus…

China's desire to lead in cutting-edge AI is bumping against its aim to control it; Zhipu warned IPO investors about the burden of complying with 6 AI rules (New York Times)
https://www.nytimes.com/2026/02/02/business/china-ai-regulations.html

Move Fast, but Obey the Rules: China’s Vision for Dominating A.I.
Beijing wants to lead the world in developing cutting-edge artificial intelligence, but it also wants companies to adhere to an increasingly complex set of rules.

"When I got into the film business, my aim was to adopt a positive persona, of a guy who fights against injustice. And it saved me, because my acting was atrocious to say the least!"
—Chuck Norris
#acting #coaching

Trump's birthday card to Epstein
New protest art on National Mall takes aim at Trump and Epstein files - The Washington Post
https://www.washingtonpost.com/dc-md-va/2026/01/19/trump-epstein-birthday-card-mall/

🥨 Biofilm streamers harden under flow, making bacterial infections harder to treat
https://phys.org/news/2026-01-biofilm-streamers-harden-bacterial-infections.html

Biofilm streamers harden under flow, making bacterial infections harder to treat
Whether in the human body or on surfaces, bacteria protect themselves from outside attackers using biofilms. Physicist Eleonora Secchi is researching how these slime-like protective films are formed, with the aim of making it easier to remove pathogenic bacteria.

🇺🇦 #NowPlaying on KEXP's #SoundsOfSurvivance
The Neighborhood Kids, Indigenous Cats:
🎵 THEY AIM AT US
#TheNeighborhoodKids #IndigenousCats
https://indigenouscats.bandcamp.com/track/they-aim-at-us-the-neighborhood-kids-indigenous-cats
https://open.spotify.com/track/11OzFg3wQmltnkvX1mzM9w

Filing: PayPay is seeking to raise up to $1.1B at a valuation of up to $13.4B in its US IPO, selling nearly 55M shares priced between $17 and $20 apiece (Arasu Kannagi Basil/Reuters)
https://www.reuters.com/business/media-telecom/p…

🇺🇦 #NowPlaying on #BBC6Music's #Afrodeutsche
Aim:
🎵 Cold Water Music
#Aim
https://aim1970.bandcamp.com/album/cold-water-music-remastered
https://open.spotify.com/track/4aY26H8RJQ6zcvovm85GVg

Alaska Republican Senator Lisa Murkowski,
fed up with being kept in the dark on combat operations,
is quietly drafting legislation that would force Congress to take a potentially explosive vote
on whether to formally authorize using military force against Iran.
Such a move signals deep fractures within GOP ranks just months before midterms.
"Ms. Murkowski described the move on Thursday as an act of desperation
to try to put some parameters around the o…

Fed-up Senate Republican may trigger explosive vote to rein in Trump
Sen. Lisa Murkowski may throw down the gauntlet, taking aim squarely at the Trump administration's Iran war, according to a report.The Alaska Republican, fed up with being kept in the dark on combat operations, is quietly drafting legislation that would force Congress to take a potentially explosive...

I donated to Give Directly https://www.givedirectly.org/ to benefit refugees
"GiveDirectly is a nonprofit that lets donors like you send money directly to the world's poorest households. In doing so, we aim to accelerate the end of extreme poverty globally."
Give Directly believes is da…

GiveDirectly: Send money to people living in poverty
GiveDirectly allows donors to send money directly to people in poverty with no strings attached. Our approach is guided by rigorous evidence of impact and our values of efficiency, transparency, and respect.

Modeling the mutational dynamics of very short tandem repeats
Amos Onn (Chair of Experimental Medicine and Therapy Research, University of Regensburg, Bioinformatics Group, Faculty of Mathematics and Computer Science, and Interdisciplinary Center for Bioinformatics, University of Leipzig), Tzipy Marx (Department of Computer Science and Applied Mathematics, Weizmann Institute of Science), Liming Tao (Cellular Tissue Genomics, Genentech), Tamir Biezuner (Department of Computer Science and Applied Mathematics, Weizmann Institute of Science), Ehud Shapiro (Department of Computer Science and Applied Mathematics, Weizmann Institute of Science), Christoph A. Klein (Chair of Experimental Medicine and Therapy Research, University of Regensburg, Fraunhofer Institute for Toxicology and Experimental Medicine Regensburg), Peter F. Stadler (Bioinformatics Group, Faculty of Mathematics and Computer Science, and Interdisciplinary Center for Bioinformatics, University of Leipzig, Max Planck Institute for Mathematics in the Sciences, Institute for Theoretical Chemistry, University of Vienna, Facultad de Ciencias, Universidad Nacional de Colombia, Center for non-coding RNA in Technology and Health, University of Copenhagen, Santa Fe Institute)
https://arxiv.org/abs/2603.25628 https://arxiv.org/pdf/2603.25628 https://arxiv.org/html/2603.25628
arXiv:2603.25628v1 Announce Type: new
Abstract: Short tandem repeats (STRs) are low-entropy regions in the genome, consisting of a short (1-6 bp) unit that is consecutively repeated multiple times. They are known for high mutational instability, due to so-called stutter-mutations, in which the number of units in the run increases or descreases. In particular, STRs with repeat unit length of 1-2 bp are prone to mutate even within several cell divisions. The extremely rapid accumulation of variation makes them interesting phylogenetic markers for retrospective single-cell lineage reconstruction. Here we model their mutational dynamics at the level of individual repeat unit type and then aggregate length variations over many STR loci with the aim of obtaining a very fast ``molecular clock''. We calibrate our model based on several datasets with known lineage structure prepared from cultured cells. We find that the mutational dynamics of STRs are reasonably consistent for a given cell line, but vary among different ones. This suggests that the dynamics are not entirely explained by mutations in caretaker genes, rather, various other factors play a role -- possibly tissue origin and differentiation state. Further data and research is necessary to asses their relative effects.
toXiv_bot_toot

"These US states want polluters to pay for the rising insurance costs of climate disasters"
#US #USA #America #Climate

Sources: China's top chipmakers, with strong government backing, aim to increase advanced chip production capacity fivefold to 100K wafers within two years (Nikkei Asia)
https://asia.nikkei.com/business/techno…

China aims for 5-fold increase in advanced chip output to meet AI demand
Backed by Beijing, Huawei and SMIC lead efforts on 7-nm and 5-nm-like production tech

🏎️ Inside Cadillac’s F1 journey: ‘Our Silverstone shakedown was a miracle’
https://www.theguardian.com/sport/2026/mar/03/cadillac-f1-valtteri-bottas-sergio-perez-graeme-lowdon

Inside Cadillac’s F1 journey: ‘Our Silverstone shakedown was a miracle’
Formula One’s newest team liken their effort to the Apollo moon landings and join the grid with the aim of becoming a championship-winning force

🇺🇦 #NowPlaying on #BBC6Music's #Afrodeutsche
Aim:
🎵 Cold Water Music
#Aim
https://aim1970.bandcamp.com/album/cold-water-music-remastered
https://open.spotify.com/track/4aY26H8RJQ6zcvovm85GVg
Please 🔁 BOOST to share what you like
- your followers don't see if you ⭐ favourite a post

Some US college students say they are using AI "humanizer" tools to alter text to avoid cheating accusations; AI detection tools now aim to catch "humanizers" (Tyler Kingkade/NBC News)
https://www.nbcnews.com/tech/internet/coll

To avoid accusations of AI cheating, college students turn to AI
On college campuses across the United States, the introduction of generative artificial intelligence has sparked a sort of arms race

“I’d try to help any president of the US because I’m a patriot,”
JP Morgan CEO Jamie Dimon told shareholders.
Even Vanity Fair commented on Dimon’s “unbridled optimism”
despite the new president’s growing list of gaffes.
A decade on, the pair’s relationship has hit rock bottom.
Trump on Thursday took aim at his one-time ally, launching a $5bn (£3.7bn) lawsuit against JP Morgan and Dimon
over claims the bank had unfairly closed his accounts for political re…

"When I got into the film business, my aim was to adopt a positive persona, of a guy who fights against injustice. And it saved me, because my acting was atrocious to say the least!"
—Chuck Norris
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