2026-04-30 21:36:07
I am currently discovering step by step the work of Mark Hallett :
https://www.thetransmitter.org/brain-stimulation/remembering-mark-hallett-leader-in-transcranial-magnetic-stimulation/
Quite a long journ…
If you compare the challenges that a Neuralink Blindsight brain implant for restoring vision still has to overcome with the challenges for The vOICe (sound-guided mental imagery)... https://www.artificialvision.com/neuralink.htm Supporting independent and open science
Massachusetts-based brain implant company Axoft raised a $55M Series A and says it tested its device in a Shanghai patient, with plans for more trials in China (Bloomberg)
https://www.bloomberg.com/news/articles/20…
cintestinalis: Tadpole larva brain (C. intestinalis)
Entire connectivity matrix for the complete brain of a larva of Ciona intestinalis. Each directed edge represents a synaptic connection from pre-synaptic cell i to post-synaptic cell j (may not be a neuron). Edge weights represent the cumulative depth of presynaptic contacts in µm.
This network has 205 nodes and 2903 edges.
Tags: Biological, Connectome, Weighted
🇺🇦 #NowPlaying on KEXP's #SonicReducer
SUX:
🎵 Brain Dead
#SUX
https://suxmusic.bandcamp.com/track/brain-dead
https://open.spotify.com/track/2HFFo5hZInkgtfitv1azeK
Many years ago, a friend said he was following “The S Diet”. It was very simple and memorable:
——
No Sweets or Seconds, except on Saturday and Sunday.
——
Simple… easy… and it actually worked for me as a way to help maintain or reduce weight (along with some mild level of exercise).
My challenge is that in the intervening years, my brain fought that and changed it to:
——
No Sweets or Seconds, except on days ending in ‘y’.
——
🤣🤦♂️
Un-doin…
US company Paradromics on brain-computer interfaces: China's recent developments and what they mean for the US https://www.paradromics.com/blog/china-bci-developments Seems at odds with how the US administration keeps eroding the scientific ecosystem in the US;
How US schools' overreliance on YouTube for educational content encourages students to drift into endless video scrolling on school-issued devices (Shalini Ramachandran/Wall Street Journal)
https://www.wsj.com/us-news/education/y…
I need to rewire my brain for my hobbies, I think. Too often I'll sit down to research something and I never run out of things to read. Meanwhile the project doesn't progress and I end up postponing it to another day (where I'll often have to start over because I forgot where I was). Brought to you by researching PiStorm and self-hosting.
🧠 Bioengineered neuronal 'circuit board' mimics conditions of the human brain
#brain
Help! I've been thinking so much about decentralized platforms and open protocols lately that my brain has become completely decentralized itself. 🙃
Time to go touch some grass.
#Fediverse #Mastodon
For those who have been hearing of a Fly Brain being uploaded, the work you've been hearing of is impressive, yet as always the pop science media has warped what happened a bit:
„The Fly Brain Breakthrough Is Real. The “First Brain Upload” Narrative Is Not.”
https://…
🇺🇦 Auf radioeins läuft...
Flea:
🎵 Maggot Brain
#NowPlaying #Flea
#newRelease 🆕 album
https://officialflea.bandcamp.com/track/maggot-brain
https://open.spotify.com/track/3poJZBl2yoeWbMMxX63YcE
How US schools' overreliance on YouTube for educational content encourages students to drift into endless video scrolling on school-issued devices (Shalini Ramachandran/Wall Street Journal)
https://www.wsj.com/us-news/education/youtube-…
EyeBrain: Left and Right Brain Lateralization Activity Classification Through Pupil Diameter and Fixation Duration
Ko Watanabe, Pooja Pol, Nicolas Gro{\ss}mann, Shoya Ishimaru, Andreas Dengel
https://arxiv.org/abs/2604.23562 https://arxiv.org/pdf/2604.23562 https://arxiv.org/html/2604.23562
arXiv:2604.23562v1 Announce Type: new
Abstract: The relationship between brain lateralization and cognitive functions is well-documented. The left hemisphere primarily handles tasks such as language and arithmetic, while the right hemisphere is involved in creative activities like drawing and music perception. Eye-tracking technology has shown the potential to reveal cognitive states by measuring ocular metrics such as pupil diameter and fixation duration. However, the ability to distinguish lateralized brain activity using these ocular metrics remains underexplored. Here, we demonstrate that pupil diameter and fixation duration can effectively classify left and right brain hemisphere activities. We obtained a considerably high classification performance, with an F1 score of 0.894. The results suggest that ocular metrics are robust indicators of lateralized brain activity and can be applied in cognitive monitoring and neurorehabilitation. Our future work expands on this by integrating these methods into real-time applications EyeBrain, potentially broadening their use across various cognitive and neurological domains.
toXiv_bot_toot
A brain implant for depression is about to be tested in humans #BCI
Two days in R-studio has made my brain an utter mess. Doing extra work on the side at night feels more heavy than ever. But sooon - I see a vaccation in the horizon
Alton Brown just called Jägermeister “German amaro” and my brain melted
How Kosovo's tech industry, driven by local companies like business outsource provider SPEEEX, is helping cut youth unemployment and changing Pristina's skyline (Bloomberg)
https://www.bloomberg.com/news/articles/2026-04-30/…
Thx Paul for a very informative and inspired Brain Inspired.
#neuroscience
The “neural fingerprint” of psychedelics was spotted among hundreds of brain scans of people on LSD, psilocybin, DMT, mescaline and ayahuasca,
pointing to a shared impact on the brain’s behaviour.
The finding emerged from a major study that combined 11 brain imaging datasets from around the world
in an effort to build a reliable picture of how the substances temporarily rewire the brain.
Dr Danilo Bzdok and his colleagues analysed more than 500 brain scans from 267 p…
The mature brain and the neuroscience of wisdom https://www.psychologytoday.com/us/blog/best-practices-in-health/202603/the-mature-brain-and-the-neuroscience-of-wisdom by William Haseltine; "A late-maturing bra…
Meta FAIR: KI-Zwilling für menschliche Neuronen
TRImodal Brain Encoder in zweiter Version veröffentlicht. Meta FAIR kann damit vorhersagen, wie das menschliche Gehirn reagiert.
https://www.heis…
No! No no brain, no brain. no brain. Toot toot toot toot [unintelligible] like-like-like-like YeAH toot. boost. toot. boost. toot. toot toot toot toot like-like-like-like mastodon no brain. mastodon no brain. boost-toot-boost-toot. never! never! never! brain. boost toot boost toot. Never think!
https://
You know you're an Internet old timer if you remember Gene Ray, self described "Cubic and Wisest Human"
That's right, the infamous Time Cube! Look it up and try to comprehend such simple math with your oneist brain noobs :-)
Microplastics may be quietly damaging your brain and fueling Alzheimer’s and Parkinson’s #health
"there is basically two sides in the #freeWill debate: compatibilists and those who find it very regrettable that they have a brain."
#compatibilism
#theplaylistsuggestion The Main Monkey Business by Rush. And... Banana Brain by Die Antwoord. Oh, and this: https://www.dailymotion.com/video/x8jpcxc
A geometry aware framework enhances noninvasive mapping of whole human brain dynamics
Song Wang, Kexin Lou, Chen Wei, Zhiyuan Sheng, Jiahao Tang, Kaining Peng, Xinke Shen, Shuhao Mei, Liang Chen, Dongfeng Gu, Quanying Liu
https://arxiv.org/abs/2604.25592 https://arxiv.org/pdf/2604.25592 https://arxiv.org/html/2604.25592
arXiv:2604.25592v1 Announce Type: new
Abstract: Non-invasive electrophysiology lacks methods that accurately reconstruct whole-brain spatiotemporal dynamics while incorporating individual cortical geometry, leaving current electroencephalography and magnetoencephalography source imaging limited by simplistic or biologically implausible priors. Here, we show that embedding participant-specific Geometric Basis Functions (GBFs), eigenmodes derived from each individual's cortical surface, provides a powerful anatomic constraint that resolves the inverse problem and improves reconstruction fidelity. The method reconstructs neural sources as linear combinations of geometric basis functions, thereby aligning source estimates with the geometric organization of neural dynamics. We validate GBF across the Meta-Source Benchmark, task-evoked data, resting-state networks, intracranial stimulation, and epilepsy data. The results demonstrate that GBF yields high localization accuracy and captures fast spatiotemporal dynamics consistent with anatomical pathways. These findings suggest that both spontaneous and evoked whole-brain activity can be described by hundreds of geometric modes, providing a compact yet accurate representation of neural sources. By linking cortical geometry to electrophysiological dynamics, GBF offers a versatile source imaging tool for both scientific and clinical applications.
toXiv_bot_toot
fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…
Spinning my brain up for our last day at PaxEast (my wife’s birthday is this weekend so have to finish prep)
Anyone on my socials happens to see me (very tall, black leather jacket, with matching harpy pins on collar) feel free to say “howdy!”
💧 Hydraulic brain: Body motion linked to fluid movement in the brain
#brain
New Study Challenges What We Know About Consciousness and the Brain
https://scitechdaily.com/new-study-challenges-what-we-know-about-consciousness-and-the-brain/
Cowboys front office explains their 'brain works' NFL Draft scouting outlook https://www.sportingnews.com/us/nfl/dallas-cowboys/news/cowboys-front-office-explains-brain-works-n…
Yes, it is. It also has this appalling change:
Sure, I know everyone (not really) loves git now. I have a GH account. I administer a Gitlab instance.
But I *USE* Subversion. It remains the definitive repository of the ASF software I work with and it’s how my brain works for version control.
Obviously I can still use svn in a shell. Most of my changes are very small, so vi and svn are fine. However, it is sad to see
Revision Implant lands oversubscribed €4M round to take brain-powered sight implant into the clinic https://bmmagazine.co.uk/get-funded/revision-implant-4m-funding-brain-visual-prosthesis/ Brain implant for restoring vision to the blind;
Next up, the Nurse Drain is just a part of the overall brain drain out of the US. Trump makes anyone who is skilled, has the opportunity and has half a brain to want to.
The Brain Drain into the USA was a key super power of the USA. Under Putin/Trump that is being destroyed. https://dmv.community/@AliceMarshall/116229967969444700
One of those things about claims of “AGI” is that to really build a human-like intelligence we’d have to simulate a human brain as whole because 1. it’s the only thing we know that produces human intelligence and 2. no one knows how it actually works.
Because of (2) it’s irrelevant what anyone says about LLMs or any other technology (with the exception of simulating a whole brain)—you can’t know if a technology is intelligent like a human because we don’t know what that means or how that works.
Fun thing, it turns out it’s impossible to simulate a whole brain with the resolution required (basically quantum physics level), and you’d have to emulate a chemical and physical environment for the brain as well (it will also need a body etc.).
You’d also have to simulate other humans with brains from which the brain can learn; but to simulate those you’d have simulate evolving humans from single-cell organisms first etc etc ad infinitum
Well, that's probably been the worst day for #Depression of the whole bloody year, but I did not get nothing done.
I finished an essay, and I think it's an important one.
https://www.
"When every student in a class processes information through the same language model, they are learning to reason through the same system. This introduces a new threat vector on the developing mind.
The model's statistical biases become the student's default framing. The model's reasoning structure becomes the student's reasoning structure. LLMs homogenize not just language but also perspective and reasoning strategies. "
🇺🇦 Auf radioeins läuft...
Kane Strang:
🎵 Two Hearts And No Brain
#NowPlaying #KaneStrang
https://open.spotify.com/track/0bwxXTxB0wYq8CndfxFYXJ
Obsidian but free and with native MCP Server. Not tried but would be glad to be rid of obsidian
https://tolaria.md
Triple Configuration of Brain Networks Based on Recurrent Neural Networks: The Synergistic Effects of Exogenous Stimuli, Task Demands, and Spontaneous Activity
Binghao Yang, Guangzong Chen
https://arxiv.org/abs/2604.23525 https://arxiv.org/pdf/2604.23525 https://arxiv.org/html/2604.23525
arXiv:2604.23525v1 Announce Type: new
Abstract: The foundation of cognitive flexibility and higher-order intelligence lies in the functional structure and activity of brain networks, which can be dynamically configured by both external environments and internal states. However, decoding these dynamics from high-dimensional neural data remains a challenge. In this study, we propose a computational framework using Recurrent Neural Networks (RNNs) with neural dynamic constraints to model source-localized resting-state EEG data from $114$ participants. We aim to clarify the "triple brain network configurations" driven by exogenous and endogenous factors, including external stimuli, information processing tasks, and spontaneous activities. Our model identifies the parietal network as a critical hub supporting these multiple configuration patterns. Furthermore, we reveal that the anterior and posterior parietal regions exhibit distinct functional specializations under different stimulus modalities. By formalizing a triple configuration framework, this work separates latent factors of brain dynamics and underscores the computational significance of parietal regions in orchestrating higher-order intelligence.
toXiv_bot_toot
🇺🇦 #NowPlaying on KEXP's #SonicReducer
The Gears:
🎵 Teenage Brain
#TheGears
https://thedefog.bandcamp.com/track/fears-for-a-teenage-brain
https://open.spotify.com/track/2nuY8QtC890uJH9fCWuTAm
Vision restoration: From prostheses to genetic-based brain-machine interfaces https://www.sciencedirect.com/science/chapter/handbook/abs/pii/B9780443222122000173 "Classically, visual prostheses were made of electrode arrays", in Handbook of …
💢 MRI scans reveal how the brain processes toxic workplace abuse
#mri
That moment when it is 7:00am and you have it strongly in your brain that YOU HAVE A MEETING AT 8:00 AM... and yet your phone's calendar doesn't show it.
So... ASSUMING the calendar failed, as they do sometimes... you pull out your computer... and find the 8am appt is NOT there either...
... and then you remember that **YOU** MOVED IT TO MONDAY! 🤣🤦♂️
The good news is that I now have an hour more this morning for work than I thought I did an hour ago! 🤣
budapest_connectome: Budapest Reference Connectome 3.0
A parameterizable consensus brain graph, derived from connectomes of 477 people, each computed from MRI datasets of the Human Connectome Project. Nodes are brain regions, and edges are weighted by the number of "tracks" that run between two nodes, as well as fiber length, fractional anisotropy and the number of occurrences in each of the 477 individuals.
This network has 1015 nodes and 121755 edges.
Tags: Biol…
By linking up visual and auditory processing in the human brain, The vOICe vision BCI can act as both a fully noninvasive visual prosthesis for the totally blind and as a research vehicle for macroscopic neuroscience https://www.artificialvision.com/neuralink.htm
wow, that #redButtonBlueButton thing fucks with my brain in ways i didn't expect.
https://xcancel.com/waitbutwhy/status/2047710215265730755
Seeing with the Brain (not the eyes) #LGN (lateral geniculate nucleus) over visual cortex for a visual prosthesis.
I check out @… every now and then but I think I just don't like the format of short videos. It's sort of a jarring experience and (nothing against loops) I don't know if it's a good thing for my brain.
Contrast that to Pixelfed where it is still images, and there is a stillness to it... it's a image, no motion, no sound, and you can stare at …
To ChatGPT: Elon Musk focuses on scalable technologies, also for the upcoming Neuralink Blindsight brain implant for the blind. At some point these implants will start to fail in patients. Will Neuralink's handling of failing brain implants prove scalable? https://chatgpt.com/share/69c85655-c24
Physical Intelligence says its new model, π0.7, can direct robots on tasks they weren't trained on, an "early sign" of generalization, surprising researchers (Connie Loizos/TechCrunch)
https://techcrunch.com/202…
Integrative neurocybernetic modeling in the era of large-scale neuroscience
Il Memming Park, Ayesha Vermani, Gonzalo G. de Polavieja, Juan \'Alvaro Gallego, Kathleen Esfahany, Shreya Saxena, Michael Orger, Auke Ijspeert, Matthew Dowling, Daniel McNamee, Srinivas C. Turaga, Zachary Mainen, Joseph J. Paton, Alfonso Renart
https://arxiv.org/abs/2604.23903 https://arxiv.org/pdf/2604.23903 https://arxiv.org/html/2604.23903
arXiv:2604.23903v1 Announce Type: new
Abstract: Large-scale neuroscience is generating rich datasets across animals, brain areas and behavioral contexts, yet our modeling efforts remains fragmented across isolated experiments. We argue that understanding behavior requires integrative neurocybernetic models: understandable dynamical models that capture the closed-loop coupling of brain, body and environment, treat the brain as a controller pursuing latent objectives, represent structured variation across scales, and scale to heterogeneous datasets. Such models shift the goal from predicting neural recordings in isolation to inferring the organizing principles that govern neural and behavioral dynamics. We outline a practical route toward this goal by combining nonlinear state-space models and meta-dynamical extensions with scalable inference, knowledge distillation, mixed open- and closed-loop training, and connectomics-informed architectures. By pooling complementary constraints from recordings, behavior, perturbations and anatomy, integrative neurocybernetic models can provide statistical amplification, few-shot generalization, and mechanistic insight into shared dynamical structure, individual variation, and the control objectives that govern behavior. This agenda offers a model-centric path from fragmented data to a mechanistic science of how brains produce behavior.
toXiv_bot_toot
🤯 The brain region associated with moral inconsistency
#brain
Neuroscientists being “surprised” that the brain doesn’t work like a computer, episode 244:
https://www.nature.com/articles/d41586-026-01554-0
Chinese brain-computer interface startup Gestala raised $21.6M co-led by Guosheng Capital and Dalton Venture at a $100M to $200M valuation, per CEO Phoenix Peng (Kate Park/TechCrunch)
https://techcrunch.com/2026/03/11/bci-startu…
AI at Meta: TRIBE v2 (Trimodal Brain Encoder), an #AI model of the human #brain, predicting neural responses to sight, sound and language https://aidemos.atmeta.com/tribev2/
fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…
Brain-wide distributed processing underlying natural vision and audition https://www.biorxiv.org/content/10.64898/2026.05.26.727967v1 "prefrontal cortex coordinated brain dynamics through synergistic interactions independently of sensory modality and previous sensory e…
⚡ Newly identified brain circuit and cells link prior experiences to appetite
#brain
A study of ~1,500 US workers finds AI use can reduce burnout but also cause "AI brain fry", a mental fatigue from using AI tools beyond one's cognitive capacity (Harvard Business Review)
https://hbr.org/2026/03/when-using-ai-leads-to-brain-fry
How psychedelics push your brain to dream while awake https://theconversation.com/how-psychedelics-push-your-brain-to-dream-while-awake-new-study-276708 Now how to nudge the brain of blind people to see through sound-guided mental image…
Crosslisted article(s) found for q-bio.NC. https://arxiv.org/list/q-bio.NC/new
[1/1]:
- Independent-Component-Based Encoding Models of Brain Activity During Story Comprehension
Kamya Hari, Taha Binhuraib, Jin Li, Cory Shain, Anna A. Ivanova
https://arxiv.org/abs/2604.24942 https://mastoxiv.page/@arXiv_csCL_bot/116486847293367640
toXiv_bot_toot
An interview with Galen Buckwalter, a BCI recipient in a Caltech brain implant study, on his recent ability to use the implant to produce musical tones (Emily Mullin/Wired)
https://www.wired.com/story/meet-the-man-making-music-with-his-brain-implant/
Brain rewires to stabilize walking during visual impairment https://neurosciencenews.com/brain-rewires-sensorimotor-walking-blindness-30721/
Resting-state functional magnetic resonance imaging study on the effects of visual status on walking-relate…
Fake AI-generated video clip of an elderly blind man seeing his wife after receiving a brain implant for restoring his vision. Will we still know what is real? Reminiscent of the Argus II media coverage before the rise of generative AI https://www.youtube.com/watch?v=CiyGOUHD2nI
Astrocytes connect specific brain regions through plastic networks (in mice) https://www.nature.com/articles/s41586-026-10426-6 "communication between distant brain regions that is mediated by plastic networks of gap junction-coupled astrocytes";
How psychedelics push your brain to dream while awake https://medicalxpress.com/news/2026-03-psychedelics-brain.html "psychedelics make the brain more likely to 'see' images from memory rather than what's actually in front of it"; mental imagery
Designing implants that don't scar the brain https://neurosciencenews.com/flexible-brain-implants-polyimide-biocompatibility-30538/ "Surprisingly, making probes 'ultra-thin' or allowing them to 'float' wirelessly didn't…
Brain-computer interfaces in healthcare: building the picks and shovels company while the giants fight over gold #BCI
Convicted Harvard scientist rebuilds career in China through controversial brain-computer interface lab https://thedebrief.org/convicted-harvard-scientist-rebuilds-career-in-china-through-controversial-brain-computer-i…
Seeing and imagining are handled by the same brain cells https://www.simonsfoundation.org/2026/05/12/seeing-and-imagining-are-handled-by-the-same-brain-cells/
"Researchers make advances in understanding how human brains ar…
Article on the ReVision Implant brain implant originating from China (WeChat): WeChat #BCI #NeuroTech
(YouTube) Jacques Carolan — The mission to get breakthrough brain treatments to everyone #neuromodulation
Max Hodak's Science Corp. is preparing to place its first sensor in a human brain https://techcrunch.com/2026/04/14/max-hodaks-science-corp-is-preparing-to-place-its-first-sensor-in-a-human-brain/ biohybrid
Why brain implants are more than a sci-fi fantasy #BCI
#Paradromics: From brain implants to neuroprosthetics | Making sense of brain-computer interface terminology https://www.paradromics.com/insights/from-brain-implants-to-neuropr…
Visual field position shapes input sampling and output routing in the superior colliculus (in mice) https://www.biorxiv.org/content/10.64898/2026.05.27.728073v1 Likely nonfunctional with brain implants in V1 for restoring vision
Thalamic oscillations distinguish natural states of consciousness in humans https://www.nature.com/articles/s41562-026-02446-z Might thalamic and other oscillations also determine if experiences appear visual or from another sensory modality? Looking for brain state control for senso…
Visual prostheses (brain implants, retinal implants) for the blind typically require high contrast scenes for good results. AI depth mapping with foveal enlargement can help get around that https://play.google.com/store/apps/details?id=vOICe.vOICe AI depth view toggle in menu …
March 25, 2026: Conscious vision and its restoration in blindness https://neuronline.sfn.org/scientific-research/conscious-vision-and-its-restoration-in-blindness
(YouTube) I don't have that white garden chair anymore, but The vOICe AI depth view would have made it still easier for Jens Naumann, blind former recipient of a Dobelle brain implant, to find the chair in my garden https://www.youtube.com/watch?v=0GsDfWqCMq
Myelin emerges as an active regulator of brain plasticity, not only a structural insulator https://www.msn.com/en-us/health/other/myelin-emerges-as-an-active-regulator-of-brain-plasticity-not-only-a-struct…
Nature: China approves brain chip to treat paralysis — a world first #Neuracle
Brain-computer interfaces for vision recovery in precortical vision loss https://www.dovepress.com/brain-computer-interfaces-for-vision-recovery-in-precortical-vision-lo-peer-reviewed-fulltext-article-EB …
(YouTube, 2024) Towards a smart bionic eye https://www.youtube.com/watch?v=AhEEEyYAegA on the Orion I brain implant and AI, with Jason Esterhuizen; "It's sort of like learning a new language. And the closest I could explain what I see is like looking up at the stars at night."
What it's like to have a brain implant for 5 years https://www.wired.com/story/synchron-brain-computer-interface-five-years-als/ (archived at
Garry Tan, VC and Y Combinator CEO: Brain computer interfaces are now giving sight back to the blind https://garryslist.org/posts/brain-computer-interfaces-are-now-giving-sight-back-to-the-blind by @…
A three-dimensional micro-instrumented neural network device #NeuroTech
New 3D device harnesses living brain cells for computing
Predicting visual mental imagery: structural and transcriptomic signatures in the human brain https://www.nature.com/articles/s42003-026-10309-6 "a distributed cortical architecture underlying VMI vividness" (VMI = visual mental imagery);