Tootfinder

A brain implant for depression is about to be tested in humans #BCI

A Brain Implant for Depression Is About to Be Tested in Humans
While many brain-computer interface companies are focused on helping paralyzed people communicate, Motif Neurotech is targeting mental health disorders.

The mature brain and the neuroscience of wisdom https://www.psychologytoday.com/us/blog/best-practices-in-health/202603/the-mature-brain-and-the-neuroscience-of-wisdom by William Haseltine; "A late-maturing bra…

The Mature Brain and the Neuroscience of Wisdom
A late-maturing brain filter in the thalamus prunes noisy sensory inputs over time, helping adults ignore distractions and focus, offering a neural basis for growing wisdom.

EyeBrain: Left and Right Brain Lateralization Activity Classification Through Pupil Diameter and Fixation Duration
Ko Watanabe, Pooja Pol, Nicolas Gro{\ss}mann, Shoya Ishimaru, Andreas Dengel
https://arxiv.org/abs/2604.23562 https://arxiv.org/pdf/2604.23562 https://arxiv.org/html/2604.23562
arXiv:2604.23562v1 Announce Type: new
Abstract: The relationship between brain lateralization and cognitive functions is well-documented. The left hemisphere primarily handles tasks such as language and arithmetic, while the right hemisphere is involved in creative activities like drawing and music perception. Eye-tracking technology has shown the potential to reveal cognitive states by measuring ocular metrics such as pupil diameter and fixation duration. However, the ability to distinguish lateralized brain activity using these ocular metrics remains underexplored. Here, we demonstrate that pupil diameter and fixation duration can effectively classify left and right brain hemisphere activities. We obtained a considerably high classification performance, with an F1 score of 0.894. The results suggest that ocular metrics are robust indicators of lateralized brain activity and can be applied in cognitive monitoring and neurorehabilitation. Our future work expands on this by integrating these methods into real-time applications EyeBrain, potentially broadening their use across various cognitive and neurological domains.
toXiv_bot_toot

Brain computer interfaces boot up multipronged legal issues https://www.afslaw.com/perspectives/news/brain-computer-interfaces-boot-multipronged-legal-issues "BCIs may be implantable or noninvasive", "Can neural data ever …

Brain Computer Interfaces Boot Up Multipronged Legal Issues | ArentFox Schiff
Forget science fiction — the race to connect computers directly to the human brain is already underway, and it is accelerating. In recent months, neurotechnology companies have expanded human clinical trials and attracted substantial investment.

multi-trillion dollar company showing off their multi-trillion dollar PhD-level galaxy brain technology

one way mastodon continues to absolutely whip bluesky's ass by an order of magnitude is by having a proper edit function, which means i didn't have to delete/redraft my mastodon post because my morning brain confused robert wilson & robert anton wilson.

How it feels to focus on anything for more than 30 minutes

Hey folx! You probably see a lot of stuff from other social networks mirrored to Mastodon, how about we do it the other way around?
Recently, I've starred to mirror my posts to Instagram, Reddit, and other platforms, and I've had quite the success. My biggest post on Instagram, which is just one screenshot of a Mastodon post, has 44.5k likes and 256k views. My

Erik Uden on Instagram: "Babe, wake up. New man-made horrors beyond comprehension dropped!! In the end of the day, these companies probably realized that, just like with AI, they can somehow use scare tactics to attract venture capital. It's still a horrifying thing to think of, but possibly overblown to get money. The headline of the Science article reads: Not alive, but not dead: disembodied human brains used for drug testing By restoring some functions to intact brains from deceased donors, the startup Bexorg hopes to create a better drug development test bed for neurodegenerative diseases, written by Sara Reardon, published on the 20th of May 2026. Though, reading this Science article made me think: aren't we the brain? Am I missing something here? Now, of course the devil lies in the detail and the article makes it clear that this startup only restores “some functions”, which is certainly more complex in action than it is in theory written here, but certain language of the article makes me question the author's understanding of what is a human. The article writes: “Just a day ago, the brain was in a living person. Now, hours after its owner died, it sits on a cart draped in tubes [...]” What do you mean “it's owner” — isn't the brain it's owner? Isn't that where it's owner is? I mean, certainly the brain had no more activity, the person must've been declared brain dead by all standards before being sent to this startup, still it's odd hearing someone donated their brain instead of saying they've donated... themselves? Also “using a set of proprietary brain-sustaining machines” is a terrible sentence I always thought the people who don't donate their full body to hospitals are religious lunatics, but this is the first time I wrote something on my organ donor card. They can take my brain, but not as one piece."
45K likes, 971 comments - erik.uden on May 21, 2026: "Babe, wake up. New man-made horrors beyond comprehension dropped!! In the end of the day, these companies probably realized that, just like with AI, they can somehow use scare tactics to attract venture capital. It's still a horrifying thing to think of, but possibly overblown to get money. The headline of the Science article reads: Not alive, but not dead: disembodied human brains used for drug testing By restoring some functions to inta…

wow, that #redButtonBlueButton thing fucks with my brain in ways i didn't expect.
https://xcancel.com/waitbutwhy/status/2047710215265730755

fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…

#theplaylistsuggestion The Main Monkey Business by Rush. And... Banana Brain by Die Antwoord. Oh, and this: https://www.dailymotion.com/video/x8jpcxc

Auf Anregung von @… habe ich mal versucht, meinen Workflow von #Logseq auf #Orgmode umzubauen.
Der erste Ansatz mit org-roam sah vielversprechend aus. Aber schon nach ku…

Yes, it is. It also has this appalling change:
Sure, I know everyone (not really) loves git now. I have a GH account. I administer a Gitlab instance.
But I *USE* Subversion. It remains the definitive repository of the ASF software I work with and it’s how my brain works for version control.
Obviously I can still use svn in a shell. Most of my changes are very small, so vi and svn are fine. However, it is sad to see

Brain-Computer-Interface: ALS-Patient nutzt Hirnimplantat 19 Monate lang
Ein ALS-Patient hat ein Brain-Computer-Interface fast zwei Jahre lang täglich zu Hause genutzt. Die Studie liefert wichtige Belege für die Alltagstauglichkeit.

Brain-Computer-Interface: ALS-Patient nutzt Hirnimplantat 19 Monate lang
Ein ALS-Patient hat ein Brain-Computer-Interface fast zwei Jahre lang täglich zu Hause genutzt. Die Studie liefert wichtige Belege für die Alltagstauglichkeit.

Triple Configuration of Brain Networks Based on Recurrent Neural Networks: The Synergistic Effects of Exogenous Stimuli, Task Demands, and Spontaneous Activity
Binghao Yang, Guangzong Chen
https://arxiv.org/abs/2604.23525 https://arxiv.org/pdf/2604.23525 https://arxiv.org/html/2604.23525
arXiv:2604.23525v1 Announce Type: new
Abstract: The foundation of cognitive flexibility and higher-order intelligence lies in the functional structure and activity of brain networks, which can be dynamically configured by both external environments and internal states. However, decoding these dynamics from high-dimensional neural data remains a challenge. In this study, we propose a computational framework using Recurrent Neural Networks (RNNs) with neural dynamic constraints to model source-localized resting-state EEG data from $114$ participants. We aim to clarify the "triple brain network configurations" driven by exogenous and endogenous factors, including external stimuli, information processing tasks, and spontaneous activities. Our model identifies the parietal network as a critical hub supporting these multiple configuration patterns. Furthermore, we reveal that the anterior and posterior parietal regions exhibit distinct functional specializations under different stimulus modalities. By formalizing a triple configuration framework, this work separates latent factors of brain dynamics and underscores the computational significance of parietal regions in orchestrating higher-order intelligence.
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By linking up visual and auditory processing in the human brain, The vOICe vision BCI can act as both a fully noninvasive visual prosthesis for the totally blind and as a research vehicle for macroscopic neuroscience https://www.artificialvision.com/neuralink.htm

The vOICe vision BCI, or a brain implant?
White paper comparing Neuralink Blindsight and other brain implants with The vOICe vision BCI for the totally blind.

💧 Hydraulic brain: Body motion linked to fluid movement in the brain
#brain

Hydraulic brain: Body motion linked to fluid movement in the brain
The brain is more mechanically connected to the body than previously appreciated, scientists report in Nature Neuroscience. Through a study using mice and simulations, the team found a potential biological mechanism underlying why exercise is thought to benefit brain health: abdominal contractions compress blood vessels connected to the spinal cord and the brain, enabling the organ to gently move within the skull. This swaying facilitates the surrounding cerebrospinal fluid to flow over the bra…

I check out @… every now and then but I think I just don't like the format of short videos. It's sort of a jarring experience and (nothing against loops) I don't know if it's a good thing for my brain.
Contrast that to Pixelfed where it is still images, and there is a stillness to it... it's a image, no motion, no sound, and you can stare at …

New York-based Probook, which is building an AI operating system for home service businesses, raised a $34M Series A led by a16z and a $6M seed led by Sequoia (Lily Mae Lazarus/Fortune)
https://fortune.com/2026/06/23/excl…

Exclusive: A founder who went from pressure washing to Wharton just raised $40 million to put AI to work for plumbers, electricians, and HVAC crews
Sequoia and a16z are betting Probook will be the AI operating system powering home services.

Revision Implant lands oversubscribed €4M round to take brain-powered sight implant into the clinic https://bmmagazine.co.uk/get-funded/revision-implant-4m-funding-brain-visual-prosthesis/ Brain implant for restoring vision to the blind;

Revision Implant lands oversubscribed €4m round to take brain-powered sight implant into the clinic
Belgian neurotech ReVision Implant secures an oversubscribed €4m round to bring cortical visual prosthesis manufacturing in-house ahead of first-in-human trials in Q3 2026.

Nighthawks

"there is basically two sides in the #freeWill debate: compatibilists and those who find it very regrettable that they have a brain."
#compatibilism

🇺🇦 #NowPlaying on KEXP's #SonicReducer
The Gears:
🎵 Teenage Brain
#TheGears
https://thedefog.bandcamp.com/track/fears-for-a-teenage-brain
https://open.spotify.com/track/2nuY8QtC890uJH9fCWuTAm

Non-Invasive Stimulation of the Brain Ended Opioid Addiction, Cigarette Craving - Slashdot
https://science.slashdot.org/story/26/06/26/221205/non-invasive-stimulation-of-the-brain-ended-opioid-addiction-cigarette-craving

The “neural fingerprint” of psychedelics was spotted among hundreds of brain scans of people on LSD, psilocybin, DMT, mescaline and ayahuasca,
pointing to a shared impact on the brain’s behaviour.
The finding emerged from a major study that combined 11 brain imaging datasets from around the world
in an effort to build a reliable picture of how the substances temporarily rewire the brain.
Dr Danilo Bzdok and his colleagues analysed more than 500 brain scans from 267 p…

No! No no brain, no brain. no brain. Toot toot toot toot [unintelligible] like-like-like-like YeAH toot. boost. toot. boost. toot. toot toot toot toot like-like-like-like mastodon no brain. mastodon no brain. boost-toot-boost-toot. never! never! never! brain. boost toot boost toot. Never think!
https://

https://www.mcsweeneys.net/articles/this-is-the-part-of-your-babys-cochlear-implant-procedure-where-i-show-them-angine-de-poitrine

This Is the Part of Your Baby’s Cochlear Implant Procedure Where I Show Them Angine de Poitrine
“It can be an overwhelming experience for your baby when the external sound processor is first turned on. It’s a lot for her brain to acclimate to. That’s wh...

Integrative neurocybernetic modeling in the era of large-scale neuroscience
Il Memming Park, Ayesha Vermani, Gonzalo G. de Polavieja, Juan \'Alvaro Gallego, Kathleen Esfahany, Shreya Saxena, Michael Orger, Auke Ijspeert, Matthew Dowling, Daniel McNamee, Srinivas C. Turaga, Zachary Mainen, Joseph J. Paton, Alfonso Renart
https://arxiv.org/abs/2604.23903 https://arxiv.org/pdf/2604.23903 https://arxiv.org/html/2604.23903
arXiv:2604.23903v1 Announce Type: new
Abstract: Large-scale neuroscience is generating rich datasets across animals, brain areas and behavioral contexts, yet our modeling efforts remains fragmented across isolated experiments. We argue that understanding behavior requires integrative neurocybernetic models: understandable dynamical models that capture the closed-loop coupling of brain, body and environment, treat the brain as a controller pursuing latent objectives, represent structured variation across scales, and scale to heterogeneous datasets. Such models shift the goal from predicting neural recordings in isolation to inferring the organizing principles that govern neural and behavioral dynamics. We outline a practical route toward this goal by combining nonlinear state-space models and meta-dynamical extensions with scalable inference, knowledge distillation, mixed open- and closed-loop training, and connectomics-informed architectures. By pooling complementary constraints from recordings, behavior, perturbations and anatomy, integrative neurocybernetic models can provide statistical amplification, few-shot generalization, and mechanistic insight into shared dynamical structure, individual variation, and the control objectives that govern behavior. This agenda offers a model-centric path from fragmented data to a mechanistic science of how brains produce behavior.
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Aldon Smith's brain donated to CTE Center as family's attorneys investigate his death at age 36 https://www.foxsports.com/articles/wcbk/aldon-smiths-brain-donated-to-cte-center-as-familys-attorneys-invest…

Obsidian but free and with native MCP Server. Not tried but would be glad to be rid of obsidian
https://tolaria.md

Brain-wide distributed processing underlying natural vision and audition https://www.biorxiv.org/content/10.64898/2026.05.26.727967v1 "prefrontal cortex coordinated brain dynamics through synergistic interactions independently of sensory modality and previous sensory e…

💢 MRI scans reveal how the brain processes toxic workplace abuse
#mri

MRI scans reveal how the brain processes toxic workplace abuse
What happens in the brain when someone witnesses toxic behavior in the workplace? Researchers at Rutgers Business School, in a first-time collaboration with the Center for Advanced Human Brain Imaging Research at the Rutgers Brain Health Institute, used an MRI scanner to find out.

🇺🇦 #NowPlaying on #BBC6Music's #NickGrimshaw
Cypress Hill:
🎵 Insane In The Brain
#CypressHill
https://matijaweiss.bandcamp.com/track/cypress-hill-insane-in-the-brain-kasabian-cover-matija-richard-elcox-edit
https://open.spotify.com/track/5Q9VftnZbrLASaW6jGpdRP

OH: I'm convinced in my conspiracy monkey brain that some libertarians are getting funding from the GOP & DNC to be a distraction.
#Overheard

Can someone explain to me how the argument “ #LLMs only produce stochastically reasonable output ” is relevant or convincing?
Like… how do you think a human brain forms a sentence? Is this a straight-forward deterministic process? Does it matter?
I use tools and processes to verify my output and so does a coding agent.
I just don't get how this is an argument that would…

Physical Intelligence says its new model, π0.7, can direct robots on tasks they weren't trained on, an "early sign" of generalization, surprising researchers (Connie Loizos/TechCrunch)
https://techcrunch.com/202…

Physical Intelligence, a hot robotics startup, says its new robot brain can figure out tasks it was never taught | TechCrunch
The new model, called π0.7, represents what the company describes as an early but meaningful step toward the long-sought goal of a general-purpose robot brain.

Well, that's probably been the worst day for #Depression of the whole bloody year, but I did not get nothing done.
I finished an essay, and I think it's an important one.
https://www.

AGI Will Not Have a Lizard Brain
Rejoice, for even though we do, verily, walk through the valley of the shadow of death, not all the phantasms we see in the valley are as dark as they appear.

Reading an article shared by a reputable source about accessible scrollable tables and the article indicates words that relate to the code by using color-coded underlines that are not links and my brain broke before I saw all the encoded px and LTR-only styles and yeah fine whatever close tab sigh.

LOL, f’kin Woz
https://www.instagram.com/reel/DYfgIwoRbYp/?igsh=MTQ1aHV2NzRzYnkwcQ==
ht…

Grand Valley State University on Instagram: "How long does it take to build a brain? 🧠💭 Apple co-founder Steve Wozniak spoke about the importance of human intelligence and innovation during his GVSU Commencement address on May 2."
6,764 likes, 92 comments - gvsu on May 18, 2026: "How long does it take to build a brain? 🧠💭 Apple co-founder Steve Wozniak spoke about the importance of human intelligence and innovation during his GVSU Commencement address on May 2.".

"Your brain is on fire."
"How could you ever know?"
"From what comes out of it... for sure..."
#humor #idiocracy #BrainOnFire

Chlorpyrifos: Pesticide tied to brain damage in children, chronic disease and other health problems #environment

Chlorpyrifos: Pesticide tied to brain damage in children, chronic disease and other health problems
Chlorpyrifos, a widely used insecticide, is strongly linked to brain damage in children.

Playing Terra Nil right now, and it's funny because from the promo stuff I thought I wouldn't like it much, yet I'm enjoying myself a lot. There's definitely a game design lesson to be leaned here.
I was absolutely correct in my assessment that the game feels like it's actively trying to make suspension of disbelief as hard as possible with its completely ridiculous mechanics that make absolutely zero sense. "That's... Not how that works at all!" Is basically playing on repeat in my brain.
Furthermore, the entire technosolutionist tenor of the game rubs me very much the wrong way. This compounds with the physics- and biology-defying (or perhaps -spiting) fictional layer in cases like the convenient magical radiation-absorbing buildings so that you can reverse radiation contamination with a few simple clicks to be extremely bad politics actually...
But... The mechanics do work together quite well to make interesting puzzles with good gameplay that includes satisfying variety and challenges. The art is wonderful, and the music and audio design are spot on. The the result of each level is immensely satisfying, and the pacing is excellent.
I guess the lesson I'm taking away from this is that really solid fundamentals can triumph over an absolute cacophony of ludonarrative dissonance. That doesn't mean that in every decision between ludonarrative harmony (or just straight up believability) and neat mechanics you should compromise towards mechanics, but it reinforces the idea that if you make the mechanics enjoyable in the abstract, players (or at least, players like me) will be willing to compromise a *lot* on whether it actually makes any sense for things to work that way.
I'm still bothered by the "use technology to fix everything" politics, which prevents this game from being one I'll enthusiastically recommend, but despite myself I am having a lot of fun with it.
#GameDesign #SolarPunk

Heute, wie auch gestern, bin ich mit meinem alten Schatz, der Nikon D7200 und dem Sigma 150–600 unterwegs. Nach dem ganzen Schwall an Automatik-, Motiv- und Fokusprogrammen der hippen spiegellosen Systemkameras ist es so etwas wie ein Brain-Reset!
Eine Wohltat, sich mit den Basics der Fotografie zu beschäftigen. Keine Automatik, alles von Hand regeln und einstellen. Einfach den Moduswähler auf M stellen und selbst zu entscheiden, wie etwas auszusehen hat.
Ich geh dann mal malen … mit Licht!

Dad brains: How fatherhood rewires the male mind https://www.bbc.com/future/article/20260417-fatherhood-how-the-male-brain-and-body-prepare-for-childcare

President, Extremely Normal Brain-Wise: Pope Weak On Crime, Also I'm Dr. Jesus Christ (Albert Burneko/Defector)
https://defector.com/president-extremely-normal-brain-wise-pope-weak-on-crime-also-im-dr-jesus-christ
http://www.memeorandum.com/260414/p150#a260414p150

Neuroscientists being “surprised” that the brain doesn’t work like a computer, episode 244:
https://www.nature.com/articles/d41586-026-01554-0

Gotta Go
A show for people who are juggling family, work, relationships, and the never-ending to-do list that lives rent-free in your brain...
Great Australian Pods Podcast Directory: https://www.greataustralianpods.com/gotta-go/

Great insight from @…
“I feel like if I could stay focused on one thing I could get it done faster, but on the other hand I feel like my brain knows what it's doing, and maybe it sends me on these "side-quests" for a good reason.”

Who Are The Brain Police?

• YouTube
• Tidal
• Deezer

fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…

New Study Challenges What We Know About Consciousness and the Brain
https://scitechdaily.com/new-study-challenges-what-we-know-about-consciousness-and-the-brain/

Ccontrast Trump’s AI Jesus post with another Trump image that came into prominence last week:
As everyone else in the room is animated by concern for the fallen man’s well-being
—they’re elevating his legs to ensure that blood is flowing to his brain
—Trump is assuming the bored-to–petulant affect he normally shows when he’s not the center of attention.
He’s standing with his arms dangling at his side with his prepared remarks open on the desk in front of him.
He’…

How Trump Keeps Getting Away With Blasphemy
Liberals struggle to understand why the president’s evangelical supporters never seem to mind his sacrilegious tendencies. They’re missing the point.

Once you realize that a Neuralink Blindsight brain implant for restoring vision will not be available for at least another decade, consider your other options more seriously.

(YouTube) Jacques Carolan — The mission to get breakthrough brain treatments to everyone #neuromodulation

🤯 The brain region associated with moral inconsistency
#brain

The brain region associated with moral inconsistency
Why don't some people practice what they preach? Researchers reveal that a brain region called the ventromedial prefrontal cortex (vmPFC) is involved. The researchers used fMRI imaging to identify brain activity patterns associated with moral behavior and judgment. People who behaved dishonestly despite judging the same behavior as immoral in others had less activity in the vmPFC, and when the researchers stimulated participants' vmPFCs, they became more morally inconsistent. The work is publis…

"none of these legacy behaviours are rational. They arise out of that bundle of behaviours inherited from our two billion years of sexually selected ancestors... If our ancestors had not had these behaviours, we would not be here. Our ancestors were not, in the sense we mean here, rational... A purely rational being — a being created ab initio rational — would not have these behaviours.
No one is proposing to build an AI with a lizard brain. It won't happen."

AGI Will Not Have a Lizard Brain
Rejoice, for even though we do, verily, walk through the valley of the shadow of death, not all the phantasms we see in the valley are as dark as they appear.

Fake AI-generated video clip of an elderly blind man seeing his wife after receiving a brain implant for restoring his vision. Will we still know what is real? Reminiscent of the Argus II media coverage before the rise of generative AI https://www.youtube.com/watch?v=CiyGOUHD2nI

fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…

Intermittent fasting triggers surprising changes in the brain #health

Intermittent fasting triggers surprising changes in the brain
Losing weight may involve rewiring the gut and the brain at the same time. In a study of obese adults, an intermittent fasting-style diet led to significant weight loss, healthier metabolic markers, and notable shifts in gut bacteria. Brain scans also revealed changes in regions tied to appetite, cravings, and self-control. The results suggest the gut microbiome and brain may work together to influence weight-loss success.

Replaced article(s) found for q-bio.NC. https://arxiv.org/list/q-bio.NC/new
[1/1]:
- Towards a Quantitative Theory of Digraph-Based Complexes and its Applications in Brain Network An...
Heitor Baldo
https://arxiv.org/abs/2409.09862 https://mastoxiv.page/@arXiv_qbioNC_bot/113152114917766699
- beta Hydroxybutyrate remodels the C99 interactome and coincides with restored organelle homeostas...
Hao Huang, Kaijing Xu, Michael Lardelli
https://arxiv.org/abs/2502.11395 https://mastoxiv.page/@arXiv_qbioNC_bot/114023675835944922
toXiv_bot_toot

An interview with Galen Buckwalter, a BCI recipient in a Caltech brain implant study, on his recent ability to use the implant to produce musical tones (Emily Mullin/Wired)
https://www.wired.com/story/meet-the-man-making-music-with-his-brain-implant/

Meet the Man Making Music With His Brain Implant
Galen Buckwalter says brain-computer interfaces will have to be enjoyable to use if the technology is going to be successful.

White paper and living document: Comparing The vOICe vision BCI with Neuralink Blindsight and other brain implants for restoring vision to the blind https://www.artificialvision.com/BCI.html
(YouTube video clips) Recent developments with The vOICe visual-to-auditory sensory substitution includ…

Researchers at Carnegie Mellon University have shown that
bacteria can learn from past experiences,
store memories across generations
and adapt their behavior to changing environments
all without a brain or nervous system
https://www.cmu.edu…

Bacteria Can Learn and Form Memories Without a Brain
Researchers at Carnegie Mellon University have shown that bacteria can learn from past experiences, store memories across generations and adapt their behavior to changing environments all without a brain or nervous system.

When will @… write about Elon Musk's Neuralink Blindsight brain implant? Still nothing in sight. #BCI

I seem to have written a wee essay about #ArtificialGeneralIntelligence #AGI
It's probably not in its final form yet, I'll probably revise a bit. Comments welcome.

AGI Will Not Have a Lizard Brain
Rejoice, for even though we do, verily, walk through the valley of the shadow of death, not all the phantasms we see in the valley are as dark as they appear.

Visual field position shapes input sampling and output routing in the superior colliculus (in mice) https://www.biorxiv.org/content/10.64898/2026.05.27.728073v1 Likely nonfunctional with brain implants in V1 for restoring vision

Required reading for programmers
https://aeon.co/essays/your-brain-does-not-process-information-and-it-is-not-a-computer

The Genetic and Environmental Architecture of the Human Functional Connectome
Tanu Raghav, Daniel Guerrero, Uttara Tipnis, Julie Sara Benny, Mintao Liu, Mario Dzemidzic, Arian Ashourvan, Alex P. Miller, Beau Ances, Jaroslaw Harezlak, Joaqu\'in Go\~ni
https://arxiv.org/abs/2604.24614 https://arxiv.org/pdf/2604.24614 https://arxiv.org/html/2604.24614
arXiv:2604.24614v1 Announce Type: new
Abstract: Functional connectivity varies across individuals due to genetic and environmental factors, yet classical twin models typically confound non-shared environment with measurement error and are largely limited to resting-state analyses. We hypothesized that: i) explicitly modeling measurement error from repeated fMRI sessions enables more accurate application of classical twin models (ACE/ADE) to functional connectivity; ii) model applicability depends on scan-length and parcellation granularity; iii) genetic and environmental effects on functional connectomes show differentiated functional modules across conditions. We extended ACE/ADE models to include a repeated-scan derived error term by analyzing monozygotic and dizygotic twins from the Young-Adult Human Connectome Project dataset. Genetic and environment variance components were estimated for all functional couplings across resting-state and task conditions, integrated across conditions using a minimum-error criterion, and analyzed using multilayer community detection across resolution scales. Functional couplings segregated into distinct categories characterized by shared environmental, additive, dominant, or epistatic influences, with a substantial fraction not meeting twin-model assumptions. Integrating across conditions revealed hierarchical community structure in genetic and environmental components observed across community resolution scales. Incorporating measurement error into twin models improves interpretability and applicability at the functional connectome level, revealing that genetic and environmental influences are structured into coherent, multiscale brain networks.
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A three-dimensional micro-instrumented neural network device #NeuroTech
New 3D device harnesses living brain cells for computing

A three-dimensional micro-instrumented neural network device - Nature Electronics
A three-dimensional soft electronic sensor and stimulator array that is integrated with a three-dimensional cultured neural network can be used to record action potential from multiple planes over a period of 6 months, monitor evolving connectivity maps and pharmacological responses, as well as construct a reservoir neural network for biocomputing.

cintestinalis: Tadpole larva brain (C. intestinalis)
Entire connectivity matrix for the complete brain of a larva of Ciona intestinalis. Each directed edge represents a synaptic connection from pre-synaptic cell i to post-synaptic cell j (may not be a neuron). Edge weights represent the cumulative depth of presynaptic contacts in µm.
This network has 205 nodes and 2903 edges.
Tags: Biological, Connectome, Weighted

Thalamic oscillations distinguish natural states of consciousness in humans https://www.nature.com/articles/s41562-026-02446-z Might thalamic and other oscillations also determine if experiences appear visual or from another sensory modality? Looking for brain state control for senso…

Thalamic oscillations distinguish natural states of consciousness in humans - Nature Human Behaviour
Chowdhury et al. report the discovery of a 19–45-Hz thalamic oscillation that is present during human wakefulness and REM sleep, but not NREM sleep.

One of the world's top centers for brain science is taking a huge gamble on a tiny, transparent fish.
The Howard Hughes Medical Institute's Janelia Research Campus near Washington, D.C., has announcedan effort to use artificial intelligence and an unusual fish called Danionella to understand how the brain controls complex behaviors like social interaction.
Janelia plans to triple the space dedicated to fish to 6,000 square feet, which will make room for thousands of new t…

Crosslisted article(s) found for q-bio.NC. https://arxiv.org/list/q-bio.NC/new
[1/1]:
- Linear equivalence of nonlinear recurrent neural networks
David G. Clark
https://arxiv.org/abs/2604.23489 https://mastoxiv.page/@arXiv_condmatdisnn_bot/116481282507557078
- Robust and Clinically Reliable EEG Biomarkers: A Cross Population Framework for Generalizable Par...
Rasmussen, Wang, Rizk, Pallab, Stuwart, Mancini, Singh, Santosh
https://arxiv.org/abs/2604.23933 https://mastoxiv.page/@arXiv_csLG_bot/116481525299245475
- Solution of a large nonlinear recurrent neural network at fixed connectivity
Albert J. Wakhloo
https://arxiv.org/abs/2604.24141 https://mastoxiv.page/@arXiv_condmatdisnn_bot/116481288377505225
- From Players to Participants: Citizen Science and Video Games to Understand Cognition
Syrine Salouhou, Edgar Dubourg, Maxwell Scott-Slade, Hugo Spiers, Antoine Coutrot
https://arxiv.org/abs/2604.24321 https://mastoxiv.page/@arXiv_csHC_bot/116481458253846078
- Persistent and anti-persistent stride-to-stride fluctuations: an ARFIMA decomposition consistent ...
Philippe Terrier
https://arxiv.org/abs/2604.24365 https://mastoxiv.page/@arXiv_qbioQM_bot/116481261245226483
- Cortex-Inspired Continual Learning: Unsupervised Instantiation and Recovery of Functional Task Ne...
Kevin McKee, Thomas Hazy, Yicong Zheng, Zacharie Bugaud, Thomas Miconi
https://arxiv.org/abs/2604.24637 https://mastoxiv.page/@arXiv_csLG_bot/116481549483167923
- Homology-based Morphometry of Brain Atrophy: Methods and Applications
Donato Quiccione, Mariam Pirashvili, Nathan Broomhead, Sean J. Fallon
https://arxiv.org/abs/2604.24714 https://mastoxiv.page/@arXiv_mathAT_bot/116481250432129653
toXiv_bot_toot

Astrocytes connect specific brain regions through plastic networks (in mice) https://www.nature.com/articles/s41586-026-10426-6 "communication between distant brain regions that is mediated by plastic networks of gap junction-coupled astrocytes";

Astrocytes connect specific brain regions through plastic networks - Nature
Communication between distant brain regions is mediated by plastic networks of gap junction-coupled astrocytes.

cintestinalis: Tadpole larva brain (C. intestinalis)
Entire connectivity matrix for the complete brain of a larva of Ciona intestinalis. Each directed edge represents a synaptic connection from pre-synaptic cell i to post-synaptic cell j (may not be a neuron). Edge weights represent the cumulative depth of presynaptic contacts in µm.
This network has 205 nodes and 2903 edges.
Tags: Biological, Connectome, Weighted

Neuroscientists long theorized that bilingual speakers must process different languages with separate patterns of brain activity.
In a new study, however, researchers found that these patterns were more alike than had been expected.
When deciding how to make a word singular or plural, for instance,
bilingual people exhibit strikingly similar brain activity regardless of whether they are speaking in their first or second language.
“It wasn’t obvious that it was going to…

Brain rewires to stabilize walking during visual impairment https://neurosciencenews.com/brain-rewires-sensorimotor-walking-blindness-30721/
Resting-state functional magnetic resonance imaging study on the effects of visual status on walking-relate…

Brain Rewires to Stabilize Walking During Visual Impairment - Neuroscience News
Neuroscience News provides research news for neuroscience, neurology, psychology, AI, brain science, mental health, robotics and cognitive sciences.

budapest_connectome: Budapest Reference Connectome 3.0
A parameterizable consensus brain graph, derived from connectomes of 477 people, each computed from MRI datasets of the Human Connectome Project. Nodes are brain regions, and edges are weighted by the number of "tracks" that run between two nodes, as well as fiber length, fractional anisotropy and the number of occurrences in each of the 477 individuals.
This network has 1015 nodes and 121755 edges.
Tags: Biol…

Ibogaine, a naturally occurring compound from a shrub native to Africa, is used to treat depression, anxiety, addiction, post-traumatic stress disorder and brain trauma. 
Because it's illegal in the United States, Americans have been traveling to unregulated clinics, often in Mexico or the Caribbean, to take the drug. 
Trump intends to sign the executive order as soon as this week, to allow its use in research
The administration doesn't plan to reclassify the drug …

Trump to sign executive order on psychedelic drug used abroad to treat PTSD
Ibogaine is used in Mexico and the Caribbean to treat depression, anxiety, addiction and brain trauma.

A computer model predicted which human brain implant channels would fail #invasive

Designing implants that don't scar the brain https://neurosciencenews.com/flexible-brain-implants-polyimide-biocompatibility-30538/ "Surprisingly, making probes 'ultra-thin' or allowing them to 'float' wirelessly didn't…

Designing Implants that Don't Scar the Brain - Neuroscience News
Neuroscience News provides research news for neuroscience, neurology, psychology, AI, brain science, mental health, robotics and cognitive sciences.

Convicted Harvard scientist rebuilds career in China through controversial brain-computer interface lab https://thedebrief.org/convicted-harvard-scientist-rebuilds-career-in-china-through-controversial-brain-computer-i…

Convicted Harvard Scientist Rebuilds Career in China Through Controversial Brain-Computer Interface Lab
Science, Tech and Defense for the Rebelliously Curious.

The vOICe vision BCI is an alternative for a Neuralink Blindsight brain implant. Recent developments include a live AI depth view https://www.youtube.com/watch?v=jE3ElPNA21g, AI scene description

Brain-computer interfaces in healthcare: building the picks and shovels company while the giants fight over gold #BCI

Brain-Computer Interfaces in Healthcare: Building the Picks and Shovels Company While the Giants Fight Over Gold
Table of Contents

Predicting visual mental imagery: structural and transcriptomic signatures in the human brain https://www.nature.com/articles/s42003-026-10309-6 "a distributed cortical architecture underlying VMI vividness" (VMI = visual mental imagery);

Seeing and imagining are handled by the same brain cells https://www.simonsfoundation.org/2026/05/12/seeing-and-imagining-are-handled-by-the-same-brain-cells/
"Researchers make advances in understanding how human brains ar…

Sensory restoration via brain-computer interfaces: A unified 2×2 framework and convergence roadmap https://arxiv.org/html/2606.15091v1
"Community Siloing: Research remains siloed. Teams developing high-density invasive stimulation interfaces rarely collaborate with teams building non-invasive se…

Why brain implants are more than a sci-fi fantasy #BCI

Why brain implants are more than a sci-fi fantasy
Researchers have been working for decades on brain-computer interfaces to help those suffering from paralysis, blindness and hearing loss.

Max Hodak's Science Corp. is preparing to place its first sensor in a human brain https://techcrunch.com/2026/04/14/max-hodaks-science-corp-is-preparing-to-place-its-first-sensor-in-a-human-brain/ biohybrid

Max Hodak’s Science Corp. is preparing to place its first sensor in a human brain | TechCrunch
Human trials on the hybrid sensor are expected to begin in the years ahead.

#Paradromics: From brain implants to neuroprosthetics | Making sense of brain-computer interface terminology https://www.paradromics.com/insights/from-brain-implants-to-neuropr…

Companies developing brain implants for restoring vision to the blind will add smartglasses to compensate for ultra-crude vision, but smartglasses offering AI scene description, real-time talking OCR and sensory substitution may render the brain implant redundant. #BCI #blindness

Myelin emerges as an active regulator of brain plasticity, not only a structural insulator https://www.msn.com/en-us/health/other/myelin-emerges-as-an-active-regulator-of-brain-plasticity-not-only-a-struct…

#Paradromics and University of Michigan complete first #Connexus BCI implantation for the FDA-approved Connect-One clinical study

The brain's code seems to be in constant flux. Neuroscientists are baffled https://www.nature.com/articles/d41586-026-01554-0 "Neurons fire much more erratically than researchers thought." Required for "time stamping" of events for long-term memories?

The brain’s code seems to be in constant flux. Neuroscientists are baffled
Neurons fire much more erratically than researchers thought. What does that mean for how the brain works?

#MIRAGE: Robust multi-modal architectures translate fMRI-to-image models from vision to mental imagery https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.10142…

Frontal cortex organization supporting audiovisual processing during naturalistic viewing https://www.nature.com/articles/s41467-026-73947-8 "ventral division primarily processes auditory information and the dorsal division processes visual inputs", "this cortical orga…

Frontal cortex organization supporting audiovisual processing during naturalistic viewing - Nature Communications
This study employed neurosurgical EEG recordings directly from the surface of the brain to reveal a dynamic ventral–dorsal gradient in the human frontal cortex that tracks the transition from auditory to visual processing during naturalistic viewing.

Spatial transcriptomics on an expanded dataset at the brain-electrode interface: exploration of variability and identification of novel biomarkers https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2026.1852774/full "…

Frontiers | Spatial transcriptomics on an expanded dataset at the brain-electrode interface: exploration of variability and identification of novel biomarkers
The foreign body reaction to implanted electrodes in the brain has long been recognized as a major challenge impacting the performance and reliability of ind...

Implanted brain-computer interface functionality during nighttime in late-stage amyotrophic lateral sclerosis https://www.nature.com/articles/s41598-026-44228-7 "When applied to night data, daytime decoders caused unintentional BCI activations in 100% of nights."

Implanted brain-computer interface functionality during nighttime in late-stage amyotrophic lateral sclerosis - Scientific Reports
Brain-computer interfaces (BCIs) hold promise as assistive communication technology for people with severe paralysis. Although such BCIs should be available 24/7, feasibility of nocturnal BCI use has not been investigated. Here, we addressed this question using data from an electrocorticography-BCI user with amyotrophic lateral sclerosis. We investigated nocturnal dynamics of neural signal features used for BCI control. Additionally, we assessed nocturnal performance of a decoder trained on day…

China has approved the world's first invasive brain-computer chip - here's what's next https://www.technologyreview.com/2026/06/01/1138133/china-world-first-brain-chip/ (archived at

China has approved the world’s first invasive brain-computer chip—here’s what’s next
The country wants to become a global leader in brain implants. Strong government support is expected to help accelerate that process.

Paralyzed artist paints again: how one brain implant drives two pathways to recovery #NeuroXess #BCI