How psychedelic drugs affect the brain https://www.sflorg.com/2026/02/ns02132601.html "High-resolution brain imaging reveals that psychedelics suppress external visual processing and instead drive visual areas to access the retrosplenial cortex, [...], thereby generating hallucinati…
fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…
fly_larva — Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`, `'ad'`, `'da'`, `'dd'`), and synapse count.
Thank you brain. 23:32 and now you start chewing on a thought that I'll need to write down to get it out of my head. Awesome. Perfect.
In der Juristerei wird das Aufkommen der LLMs begeistert gefeiert. Man versucht sich zu profilieren. Man ist vielleicht besorgt, dass die Stundensätze herunter gehen könnten. Aber sonst? Und dann diese Studie, die zeigt, dass bei Benutzung von LLMs die cognitive Kapazität und damit auch die Qualität dauernd nach unten zeigt. Kurz: Ein LLM-Anwalt bietet teure 0815-Soße, die man auch ohne Anwalt haben kann.
this combination pot store & "prison style bootcamp" on delancey street never fails to make my brain grind. all i can imagine is allen ginsberg overseeing workouts & screaming POT IS FUN!!!! at you while you're on the elliptical or some shit. (and yes, i get that weed & exercise go together just fine. it's more the bootcamp part.) #nyc
Today’s one small action to push SF progressives away from the embrace of car brain.
All candidates who have filed in that district oppose the park, so it’s an easy call that she would be my first place vote if I lived there, regardless. But unless that stance changes, am I spending my precious time on her campaign? Nah. #sfpol
@…
I haven't seen latest Star Wars (because latest Star Wars stories are for brain dead) and I haven't seen Hidden Fortress, but just by looking at pictures I must ask - what are the similarities?🤔
Series B, Episode 12 - The Keeper
FOOL: [Singing] I sing you of the Tents, my Master, Charl of the Goths, I sing you of the golden tents, Where your fathers wait to greet you...
BLAKE: [Examining the talisman] It's gone, the brain print's gone!
https://blake.torpidity.net/m/212/515…
Woke up at 5:00 am spontaneously and my brain keeps going like sixty 😖😑😵💫
"Most importantly, it means countries should do everything they can to retain their best homegrown entrepreneurs"
The exorbitant privilege of the US brain gain is fading - https://giftarticle.ft.com/giftarticle/actions/redeem/70036c24-2423-4078-97bb-7e5596645063
(PDF on Zenodo) White paper: Comparing The vOICe vision BCI for the blind with Neuralink Blindsight and other brain implants for restoring vision #BCI
budapest_connectome: Budapest Reference Connectome 3.0
A parameterizable consensus brain graph, derived from connectomes of 477 people, each computed from MRI datasets of the Human Connectome Project. Nodes are brain regions, and edges are weighted by the number of "tracks" that run between two nodes, as well as fiber length, fractional anisotropy and the number of occurrences in each of the 477 individuals.
This network has 1015 nodes and 112890 edges.
Tags: Biol…
She's Honestly Mental
Hosted by Corrina Rawlinson: ADHD brain (medicated), mum of three, and proud mental health hospital alumni who went from writing suicide letters to building a movement...
Great Australian Pods Podcast Directory: https://www.greataustralianpods.com/shes-h
Parallel Neuron Groups in the Drosophila Brain
Robert Worden
https://arxiv.org/abs/2512.10525 https://arxiv.org/pdf/2512.10525 https://arxiv.org/html/2512.10525
arXiv:2512.10525v1 Announce Type: new
Abstract: The full connectome of an adult Drosophila enables a search for novel neural structures in the insect brain. I describe a new neural structure, called a Parallel Neuron Group (PNG). Two neurons are called parallel if they share a significant number of input neurons and output neurons. Most pairs of neurons in the Drosophila brain have very small parallel match. There are about twenty larger groups of neurons for which any pair of neurons in the group has a high match. These are the parallel groups. Parallel groups contain only about 1000 out of the 65,000 neurons in the brain, and have distinctive properties. There are groups in the right mushroom bodies, the antennal lobes, the lobula, and in two central neuropils (GNG and EB). Most parallel groups do not have lateral symmetry. A group usually has one major input neuron, which inputs to all the neurons in the group, and a small number of major output neurons. The major input and output neurons are laterally asymmetric. Parallel neuron groups present puzzles, such as: what does a group do, that could not be done by one larger neuron? Do all neurons in a group fire in synchrony, or do they perform different functions? Why are they laterally asymmetric? These may merit further investigation.
toXiv_bot_toot
recent-ish reading/rereading. #books
While Elon Musk is pushing hard to get the Neuralink Blindsight brain implant out, The vOICe vision BCI can grow organically, no matter how long it takes https://www.artificialvision.com/neuralink.htm Applied psychohistory
#LB Que gente maluca. Uma IA jamais deveria ter acesso direto ao seu sistema operacional, com permissões para compilar ou instalar programas. Isto é bšsico!
https://mastodon.social/@SteveThompson
Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes,
the DNA blueprint for these cells is essentially the same.
Where do those differences come from?
Scientists are realizing the defining qualities that make up each cell actually lie in a cousin of DNA called RNA.
RNA was long considered DNA’s boring biochemical relative.
Researchers thought it merely takes the genetic information stored in DNA and delivers i…
Starting the year with a broken brain?
I finally replaced the battery in my AirTag, but now I am left with the dead battery that I need to dispose of.
I'm likely to forget to take it to the supermarket's recycling box, and my brain is still locked in the "don't leave it laying around, or my child might eat it", even though he's 11 now 😅
@… and
@… might like this.
I think this is interesting, from "Frontiers in Neuroscience" mag. New "HYPOTHESIS AND THEORY article" by Joachim Keppler, head of Department of Consciousness …
Allometric scaling of brain activity explained by avalanche criticality
Tiago S. A. N. Sim\~oes, Jos\'e S. Andrade Jr., Hans J. Herrmann, Stefano Zapperi, Lucilla de Arcangelis
https://arxiv.org/abs/2512.10834 https://arxiv.org/pdf/2512.10834 https://arxiv.org/html/2512.10834
arXiv:2512.10834v1 Announce Type: new
Abstract: Allometric scaling laws, such as Kleiber's law for metabolic rate, highlight how efficiency emerges with size across living systems. The brain, with its characteristic sublinear scaling of activity, has long posed a puzzle: why do larger brains operate with disproportionately lower firing rates? Here we show that this economy of scale is a universal outcome of avalanche dynamics. We derive analytical scaling laws directly from avalanche statistics, establishing that any system governed by critical avalanches must exhibit sublinear activity-size relations. This theoretical prediction is then verified in integrate-and-fire neuronal networks at criticality and in classical self-organized criticality models, demonstrating that the effect is not model-specific but generic. The predicted exponents align with experimental observations across mammal species, bridging dynamical criticality with the allometry of brain metabolism. Our results reveal avalanche criticality as a fundamental mechanism underlying Kleiber-like scaling in the brain.
toXiv_bot_toot
RE: https://social.linux.pizza/@midtsveen/115873428590286252
This is also why I don't but do, but don't delete toots after 7 days. I want to keep a record of my thoughts so I can see how my brain patterns shift over time, but sometimes the chi…
fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…
fly_larva — Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`, `'ad'`, `'da'`, `'dd'`), and synapse count.
I'm so glad not every country is throttling scientific research!
An international team have created a simple blood test that can be carried out at home and sent in by post to discover early brain changes consistent with Alzheimer ➡️ 10 - 20 yrs before dementia sets in.
[from Goteborgs-posten
Docs: London-based AI chip startup Olix, founded by James Dacombe, CEO of brain monitoring startup CoMind, raised $220M led by Hummingbird at a $1B valuation (Tim Bradshaw/Financial Times)
https://giftarticle.ft.com/giftarticle/actions/redeem/b3e70…
A new study suggests that #dementia may be driven in part by faulty blood flow in the brain.
Researchers found that losing a key lipid causes blood vessels to become overactive,
disrupting circulation and starving brain tissue.
When the missing molecule was restored, normal blood flow returned.
This discovery opens the door to new treatments aimed at fixing vascular problems in …
cintestinalis: Tadpole larva brain (C. intestinalis)
Entire connectivity matrix for the complete brain of a larva of Ciona intestinalis. Each directed edge represents a synaptic connection from pre-synaptic cell i to post-synaptic cell j (may not be a neuron). Edge weights represent the cumulative depth of presynaptic contacts in µm.
This network has 205 nodes and 2903 edges.
Tags: Biological, Connectome, Weighted
(LinkedIn) As of today, not only the Neuralink Blindsight brain implant has FDA Breakthrough Device Designation, but also ReVision Implant https://www.linkedin.com/posts/frederikceyssens_with-great-pleasure-im-announcing-that…
Heads Up With Em
The series will highlight themes of resilience, survival, and gaining a new perspective on life, while offering a resource for those currently battling brain cancer...
Great Australian Pods Podcast Directory: https://www.greataustralianpods.com/heads-up-with-e…
Source: Sam Altman's Merge Labs, which seeks to read brain activity using ultrasound, is being spun out of LA-based nonprofit Forest Neurotech (Emily Mullin/Wired)
https://www.wired.com/story/sam-altman-brain-computer-interf…
What will blind recipients of a Neuralink Blindsight brain implant be able to do that they cannot do with smartglasses performing visual-to-auditory sensory substitution, talking OCR and AI scene description?
Grok AI: https://x.com/i/grok/share/e7e93359abb5491aa0f76a802da2461e
this is a joe mcgasko appreciation toot. at least for my brain, there is no calmer way to start a week than his monday morning @… show. #radio
Flexion, which is building a full autonomy stack for humanoid robots, raised a $50M Series A from DST Global Partners, NVentures, and others, after a $7M seed (Mary Ann Azevedo/Crunchbase News)
https://news.crunchbase.com/venture/robotic-brain-building-star…
(YouTube) Samarth by Hyundai: The vOICe vision BCI in India https://www.youtube.com/watch?v=qtgpoT3eff0&t=692s Will Neuralink Blindsight and other brain implants for restoring vision ever work for congenitally blind people? Probably not.
budapest_connectome: Budapest Reference Connectome 3.0
A parameterizable consensus brain graph, derived from connectomes of 477 people, each computed from MRI datasets of the Human Connectome Project. Nodes are brain regions, and edges are weighted by the number of "tracks" that run between two nodes, as well as fiber length, fractional anisotropy and the number of occurrences in each of the 477 individuals.
This network has 1015 nodes and 54480 edges.
Tags: Biolo…
People with the highest daily intake of caffeinated coffee had an 18% lower risk of developing dementia compared to those with the lowest such intake, according to a study based on responses to questionnaires by 132,000 U.S. adults spanning four decades.
fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…
fly_larva — Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`, `'ad'`, `'da'`, `'dd'`), and synapse count.
Paradromics says it received FDA approval for a human trial of its Connexus brain implant, aimed at restoring speech to those with severe motor impairments (Emily Mullin/Wired)
https://www.wired.com/story/paradromics-gets-fda-approval-to-trial-…
#Subsense expands financing to $27 million to accelerate R&D for non-surgical brain-computer interfaces https://www.busine…
RE: https://mas.to/@seeingwithsound/115694827245576278
The vOICe vision BCI has the same goal of providing functional vision, without the brain surgery and brain implant
fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…
fly_larva — Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`, `'ad'`, `'da'`, `'dd'`), and synapse count.
Boston-based Neurable, which builds an OS for brain-computer interfaces, raised a $35M Series A led by Spectrum Moonshot Fund, bringing its total raised to $65M (Brock E.W. Turner/Axios)
https://www.axios.com/pro/health-tech-deals/2025/12/19/neurable-r…
fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…
fly_larva — Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`, `'ad'`, `'da'`, `'dd'`), and synapse count.
(YouTube) ReVision Implant's Occular brain implant for restoring vision #FLAIRVISION
Tricks for using Google Gemini Live AI scene description in combination with The vOICe visual-to-auditory sensory substitution for the blind #blind
fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…
fly_larva — Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`, `'ad'`, `'da'`, `'dd'`), and synapse count.
budapest_connectome: Budapest Reference Connectome 3.0
A parameterizable consensus brain graph, derived from connectomes of 477 people, each computed from MRI datasets of the Human Connectome Project. Nodes are brain regions, and edges are weighted by the number of "tracks" that run between two nodes, as well as fiber length, fractional anisotropy and the number of occurrences in each of the 477 individuals.
This network has 1015 nodes and 54480 edges.
Tags: Biolo…
WIRED, 2004: The long tail https://www.wired.com/2004/10/tail/ Will The vOICe vision BCI cover more of the long tail of blindness cases than brain implants, retinal implants and optogenetics combined? Think of developing countries, types of blindness, device lifetime, etc. Economy of abundance vs Pareto…
(2024) Rapid desensitization to retinally stabilized flickering stimuli https://iovs.arvojournals.org/article.aspx?articleid=2797077 To the extent that mechanisms for perceptual fading are in the brain it could have consequences for visual cortical prostheses.
budapest_connectome: Budapest Reference Connectome 3.0
A parameterizable consensus brain graph, derived from connectomes of 477 people, each computed from MRI datasets of the Human Connectome Project. Nodes are brain regions, and edges are weighted by the number of "tracks" that run between two nodes, as well as fiber length, fractional anisotropy and the number of occurrences in each of the 477 individuals.
This network has 1015 nodes and 63448 edges.
Tags: Biolo…
budapest_connectome: Budapest Reference Connectome 3.0
A parameterizable consensus brain graph, derived from connectomes of 477 people, each computed from MRI datasets of the Human Connectome Project. Nodes are brain regions, and edges are weighted by the number of "tracks" that run between two nodes, as well as fiber length, fractional anisotropy and the number of occurrences in each of the 477 individuals.
This network has 1015 nodes and 112890 edges.
Tags: Biol…
The vOICe web app is the richest functional vision option for the totally blind that is just one click away - no brain surgery, and for free https://www.seeingwithsound.com/webvoice/webvoice.htm but yes, it's like learning a new language, or braille, or chess, or...
(IEEE Spectrum) 11 Amazing engineering events in 2026: Brain chip helps blind people see https://spectrum.ieee.org/new-technology-2026 on Elon Musk and Neuralink Blindsight: "some experts worry he is overpromising on the quality of the brain-computer interface";
Renewed work toward a visual prosthesis (brain implant) in the #LGN instead of visual cortex https://nin.nl/news/first-ever-recording-of-a-crucial-visual-structure-in-the…
In the context of visual prostheses for the blind, more scientists should be working on "mental imagery engineering" to nudge the human brain toward making the best of degraded or transformed visual input https://www.google.com/search?q="mental imagery engineering"