An interview with Galen Buckwalter, a BCI recipient in a Caltech brain implant study, on his recent ability to use the implant to produce musical tones (Emily Mullin/Wired)
https://www.wired.com/story/meet-the-man-making-music-with-his-brain-implant/
The 'secret connections' of the brain: a connectomic reserve for neuroplasticity? #neuroscience
Not the usual stuff I post.
fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…
A study in Nature Health finds that microplastics and nanoplastics
were at a higher level in brain tumour samples from living patients
than in healthy human brain samples from cadavers,
with a correlation between microplastic surface area and tumour proliferation. https://go.nature.com/4cuBK4I…
Canadians, do you think, like Canadaland's Stephen Marche, that Canadian nationalism is a 1960s - Waffle, I guess - phenomenon?
"I just don't think of that period [post-WWI] as being hyper-nationalistic. I think of nationalism as born in 1965 from Margaret Atwood's brain."
As a historian, I know that left nationalism in the 60s was an important phenomenon, but the notion that some might think that Canadian nationalism was born then hurts my brain.
A wandering mind is not the enemy of focus. It is the foundation of it. Your brain does not run on intensity. It runs on rhythm.
#NeuroScience
You try and help. You try and make things a little better in whatever small way you can. You think, “hey, maybe at least there will be some respite now… maybe things can start to get better” and, just as your foolish little brain starts to believe it, the fuckers who fuck everything up for everyone but themselves – and somehow are never held to account for any of it – go and fuck things up even further. It’s fucking depressing. I mean I don’t know how we’re not all just fucking depressed eve…
fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…
Would getting a Neuralink Blindsight brain implant for restoring vision be worth it? #BCI
Brain-Computer-Interface: zunehmender Einsatz, Risiken, lückenhafte Rechtslage
BCIs können helfen, motorische Fähigkeiten und Kommunikation wieder zu ermöglichen. Das Potenzial ist enorm, Rechtslage und Ethik noch weitgehend ungeklärt.
The most common strategy for "AI-proofing" your career is to get good at using AI tools.
This is futile, because no one is using AI tools to make things that are *good.* The goal is to check the box on the project plan at a predictable pace. As long as the box is checked, quality is not a factor.
To AI-proof your job, get out of the project game.
reluctantly bidding adieu to albuquerque & the brilliant freaks of the grateful dead scholars' caucus, a just exactly perfect escape from consensus reality. mind & heart full, brain & body crisped. presentations described in alt text! #deadscholarsunite
Sweet jesus, I think the brain worms have worked on this one beyond remedy. The whole thing is toast.
En la mani del #1deMayo un compañero me ha hablado de este artículo sobre la salud del uso de la #ia en el entorno laboral. No lo he leído aún pero me ha dicho que es muy interesante lo que plantea
The office yesterday afternoon... donated a gig to a fundraiser for a young father battling a rare type of brain cancer.
#ThingsThatDontHappenInAnyOtherDevelopedCountry
Q&A with Skild AI CEO Deepak Pathak on building a general-purpose brain for robots, standing out among big tech's robotics efforts, the path to AGI, and more (Alex Heath/Sources)
https://sources.news/p/skild-ai-ceo-robotics-brain-davos
budapest_connectome: Budapest Reference Connectome 3.0
A parameterizable consensus brain graph, derived from connectomes of 477 people, each computed from MRI datasets of the Human Connectome Project. Nodes are brain regions, and edges are weighted by the number of "tracks" that run between two nodes, as well as fiber length, fractional anisotropy and the number of occurrences in each of the 477 individuals.
This network has 1015 nodes and 63448 edges.
Tags: Biolo…
For those who have been hearing of a Fly Brain being uploaded, the work you've been hearing of is impressive, yet as always the pop science media has warped what happened a bit:
„The Fly Brain Breakthrough Is Real. The “First Brain Upload” Narrative Is Not.”
https://…
How to improve memory, mitigate dementia & reverse brain aging:
1️⃣ Take a multivitamin daily.
2️⃣ Increase choline intake. (Eggs)
3️⃣ Eat more blueberries. (1 cup/daily)
4️⃣ Aerobic exercise (60% of max heart rate)
▶️ The Fastest Way to Reverse Brain Aging (Science-backed)
https://
fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…
fly_larva — Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`, `'ad'`, `'da'`, `'dd'`), and synapse count.
US company Paradromics on brain-computer interfaces: China's recent developments and what they mean for the US https://www.paradromics.com/blog/china-bci-developments Seems at odds with how the US administration keeps eroding the scientific ecosystem in the US;
Massachusetts-based brain implant company Axoft raised a $55M Series A and says it tested its device in a Shanghai patient, with plans for more trials in China (Bloomberg)
https://www.bloomberg.com/news/articles/20…
EyeBrain: Left and Right Brain Lateralization Activity Classification Through Pupil Diameter and Fixation Duration
Ko Watanabe, Pooja Pol, Nicolas Gro{\ss}mann, Shoya Ishimaru, Andreas Dengel
https://arxiv.org/abs/2604.23562 https://arxiv.org/pdf/2604.23562 https://arxiv.org/html/2604.23562
arXiv:2604.23562v1 Announce Type: new
Abstract: The relationship between brain lateralization and cognitive functions is well-documented. The left hemisphere primarily handles tasks such as language and arithmetic, while the right hemisphere is involved in creative activities like drawing and music perception. Eye-tracking technology has shown the potential to reveal cognitive states by measuring ocular metrics such as pupil diameter and fixation duration. However, the ability to distinguish lateralized brain activity using these ocular metrics remains underexplored. Here, we demonstrate that pupil diameter and fixation duration can effectively classify left and right brain hemisphere activities. We obtained a considerably high classification performance, with an F1 score of 0.894. The results suggest that ocular metrics are robust indicators of lateralized brain activity and can be applied in cognitive monitoring and neurorehabilitation. Our future work expands on this by integrating these methods into real-time applications EyeBrain, potentially broadening their use across various cognitive and neurological domains.
toXiv_bot_toot
Somebody send help i just looked up at some elongated fuzzy clouds and my brain went "wow i need to tweak the stigmators"
"We're just going to run a physical simulation of a human brain to achieve AGI"
"Won't the brain die instantly if it's without a body and oxygen supply etc?"
"Well, we'll just also simulate a body."
"Won't the body die instantly if it's in a vacuum?
"Fine, we'll just simulate an atmosphere too."
"Won't the body die if it's without food and light and gravity and stimulation?"
"Fine, we'll just simulate all the physical processes on the Earth."
"Won't the Earth just freeze instantly without the Sun being there?"
"Fine, we'll just simulate the sun, too."
"Will the solar system work properly if there's only the sun? What about gravitational influences of other mass in the galaxy, what about cosmic rays?"
"Fine, we'll just simulate the whole universe, too."
“Brain Drain” or Temporary Wartime Realities? How the Number and Quality of Applicants to Ukrainian Higher Education Institutions Have Changed Since the Start of the Full-Scale Invasion: https://benborges.xyz/2026/02/19/brain-drain-or-temporary-wartime.html
Never put any important information in a pop-up. The thumb is trained to close the box before the brain has a chance to take it in.
Deepinder Goyal, who stepped down as Zomato's CEO, raised $54M at a $190M valuation for Temple, which aims to make high-performance wearables for elite athletes (Jagmeet Singh/TechCrunch)
https://techcrunch.com/2026/02/27/after-zoma…
I need to rewire my brain for my hobbies, I think. Too often I'll sit down to research something and I never run out of things to read. Meanwhile the project doesn't progress and I end up postponing it to another day (where I'll often have to start over because I forgot where I was). Brought to you by researching PiStorm and self-hosting.
Two days in R-studio has made my brain an utter mess. Doing extra work on the side at night feels more heavy than ever. But sooon - I see a vaccation in the horizon
No! No no brain, no brain. no brain. Toot toot toot toot [unintelligible] like-like-like-like YeAH toot. boost. toot. boost. toot. toot toot toot toot like-like-like-like mastodon no brain. mastodon no brain. boost-toot-boost-toot. never! never! never! brain. boost toot boost toot. Never think!
https://
It's not that The vOICe vision BCI is so good, it's that invasive BCIs for (restoring) vision are far worse than often claimed. The human brain is not plug-and-play. https://chatgpt.com/share/69f448a9-de04-83eb-9720-98a2f66ca7e5
Thx Paul for a very informative and inspired Brain Inspired.
#neuroscience
Meta FAIR: KI-Zwilling für menschliche Neuronen
TRImodal Brain Encoder in zweiter Version veröffentlicht. Meta FAIR kann damit vorhersagen, wie das menschliche Gehirn reagiert.
https://www.heis…
Help! I've been thinking so much about decentralized platforms and open protocols lately that my brain has become completely decentralized itself. 🙃
Time to go touch some grass.
#Fediverse #Mastodon
cintestinalis: Tadpole larva brain (C. intestinalis)
Entire connectivity matrix for the complete brain of a larva of Ciona intestinalis. Each directed edge represents a synaptic connection from pre-synaptic cell i to post-synaptic cell j (may not be a neuron). Edge weights represent the cumulative depth of presynaptic contacts in µm.
This network has 205 nodes and 2903 edges.
Tags: Biological, Connectome, Weighted
A geometry aware framework enhances noninvasive mapping of whole human brain dynamics
Song Wang, Kexin Lou, Chen Wei, Zhiyuan Sheng, Jiahao Tang, Kaining Peng, Xinke Shen, Shuhao Mei, Liang Chen, Dongfeng Gu, Quanying Liu
https://arxiv.org/abs/2604.25592 https://arxiv.org/pdf/2604.25592 https://arxiv.org/html/2604.25592
arXiv:2604.25592v1 Announce Type: new
Abstract: Non-invasive electrophysiology lacks methods that accurately reconstruct whole-brain spatiotemporal dynamics while incorporating individual cortical geometry, leaving current electroencephalography and magnetoencephalography source imaging limited by simplistic or biologically implausible priors. Here, we show that embedding participant-specific Geometric Basis Functions (GBFs), eigenmodes derived from each individual's cortical surface, provides a powerful anatomic constraint that resolves the inverse problem and improves reconstruction fidelity. The method reconstructs neural sources as linear combinations of geometric basis functions, thereby aligning source estimates with the geometric organization of neural dynamics. We validate GBF across the Meta-Source Benchmark, task-evoked data, resting-state networks, intracranial stimulation, and epilepsy data. The results demonstrate that GBF yields high localization accuracy and captures fast spatiotemporal dynamics consistent with anatomical pathways. These findings suggest that both spontaneous and evoked whole-brain activity can be described by hundreds of geometric modes, providing a compact yet accurate representation of neural sources. By linking cortical geometry to electrophysiological dynamics, GBF offers a versatile source imaging tool for both scientific and clinical applications.
toXiv_bot_toot
One of those things about claims of “AGI” is that to really build a human-like intelligence we’d have to simulate a human brain as whole because 1. it’s the only thing we know that produces human intelligence and 2. no one knows how it actually works.
Because of (2) it’s irrelevant what anyone says about LLMs or any other technology (with the exception of simulating a whole brain)—you can’t know if a technology is intelligent like a human because we don’t know what that means or how that works.
Fun thing, it turns out it’s impossible to simulate a whole brain with the resolution required (basically quantum physics level), and you’d have to emulate a chemical and physical environment for the brain as well (it will also need a body etc.).
You’d also have to simulate other humans with brains from which the brain can learn; but to simulate those you’d have simulate evolving humans from single-cell organisms first etc etc ad infinitum
How US schools' overreliance on YouTube for educational content encourages students to drift into endless video scrolling on school-issued devices (Shalini Ramachandran/Wall Street Journal)
https://www.wsj.com/us-news/education/youtube-…
Triple Configuration of Brain Networks Based on Recurrent Neural Networks: The Synergistic Effects of Exogenous Stimuli, Task Demands, and Spontaneous Activity
Binghao Yang, Guangzong Chen
https://arxiv.org/abs/2604.23525 https://arxiv.org/pdf/2604.23525 https://arxiv.org/html/2604.23525
arXiv:2604.23525v1 Announce Type: new
Abstract: The foundation of cognitive flexibility and higher-order intelligence lies in the functional structure and activity of brain networks, which can be dynamically configured by both external environments and internal states. However, decoding these dynamics from high-dimensional neural data remains a challenge. In this study, we propose a computational framework using Recurrent Neural Networks (RNNs) with neural dynamic constraints to model source-localized resting-state EEG data from $114$ participants. We aim to clarify the "triple brain network configurations" driven by exogenous and endogenous factors, including external stimuli, information processing tasks, and spontaneous activities. Our model identifies the parietal network as a critical hub supporting these multiple configuration patterns. Furthermore, we reveal that the anterior and posterior parietal regions exhibit distinct functional specializations under different stimulus modalities. By formalizing a triple configuration framework, this work separates latent factors of brain dynamics and underscores the computational significance of parietal regions in orchestrating higher-order intelligence.
toXiv_bot_toot
The “neural fingerprint” of psychedelics was spotted among hundreds of brain scans of people on LSD, psilocybin, DMT, mescaline and ayahuasca,
pointing to a shared impact on the brain’s behaviour.
The finding emerged from a major study that combined 11 brain imaging datasets from around the world
in an effort to build a reliable picture of how the substances temporarily rewire the brain.
Dr Danilo Bzdok and his colleagues analysed more than 500 brain scans from 267 p…
budapest_connectome: Budapest Reference Connectome 3.0
A parameterizable consensus brain graph, derived from connectomes of 477 people, each computed from MRI datasets of the Human Connectome Project. Nodes are brain regions, and edges are weighted by the number of "tracks" that run between two nodes, as well as fiber length, fractional anisotropy and the number of occurrences in each of the 477 individuals.
This network has 1015 nodes and 63448 edges.
Tags: Biolo…
How Kosovo's tech industry, driven by local companies like business outsource provider SPEEEX, is helping cut youth unemployment and changing Pristina's skyline (Bloomberg)
https://www.bloomberg.com/news/articles/2026-04-30/…
fly_hemibrain: Fly hemibrain (2020)
A synaptic map of the hemibrain connectome of fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using EM reconstruction techniques. Neurons are labeled by their type. Edges are annotated by the connection strength between the neurons.
This network has 21739 nodes and 4259624 edges.
Tags: Biological, Connectome, Weighted, Metadata
(YouTube) China's government-backed BCI push could bring brain-computer tech to the masses within 3 to 5 years #BCI
The unusual electronic and optical properties of #perovskites have long been touted as useful for improving solar cells and television screens,
but these materials have never quite hit the big time.
Existing approaches have hoovered up all the investment and attention, and perovskites remain confined to specialist applications.
Now researchers at Empa, ETH Zurich and the Politecnico…
Generalization and extinction of learned fear alter primary sensory input to the brain (of mice) https://www.biorxiv.org/content/10.64898/2026.02.25.708099v1
The vOICe vision BCI app for Android crossed the 600,000 cumulative installs mark from Google Play https://play.google.com/store/apps/details?id=vOICe.vOICe Compare this to the number of Neuralink Blindsight brain implants in humans to date (spoiler: zero).
fly_hemibrain: Fly hemibrain (2020)
A synaptic map of the hemibrain connectome of fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using EM reconstruction techniques. Neurons are labeled by their type. Edges are annotated by the connection strength between the neurons.
This network has 21739 nodes and 4259624 edges.
Tags: Biological, Connectome, Weighted, Metadata
https://networks.skewed.de/net/fly_hemibrain
Ridiculogram:
Sources: Dell, Lenovo, and other PC makers are working with Nvidia on laptops using the Arm-based Nvidia-MediaTek system-on-a-chip, which could come in H1 2026 (Yang Jie/Wall Street Journal)
https://www.wsj.com/tech/nvidia-wants-to-be-the-brain-of-co…
fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…
(YouTube) Your brain is a dream machine | Anil Seth on the neuroscience of active inference https://www.youtube.com/watch?v=HYUoS0GkGCs That's what sensory substitution for the blind is tapping into: we see with the brain, not the eyes (Paul Bach-y-Rita).
Chinese brain-computer interface startup Gestala raised $21.6M co-led by Guosheng Capital and Dalton Venture at a $100M to $200M valuation, per CEO Phoenix Peng (Kate Park/TechCrunch)
https://techcrunch.com/2026/03/11/bci-startu…
fly_hemibrain: Fly hemibrain (2020)
A synaptic map of the hemibrain connectome of fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using EM reconstruction techniques. Neurons are labeled by their type. Edges are annotated by the connection strength between the neurons.
This network has 21739 nodes and 4259624 edges.
Tags: Biological, Connectome, Weighted, Metadata
Brain implants: What's standing in the way of pivotal trials, FDA approval #BCI
AI at Meta: TRIBE v2 (Trimodal Brain Encoder), an #AI model of the human #brain, predicting neural responses to sight, sound and language https://aidemos.atmeta.com/tribev2/
To ChatGPT: Elon Musk focuses on scalable technologies, also for the upcoming Neuralink Blindsight brain implant for the blind. At some point these implants will start to fail in patients. Will Neuralink's handling of failing brain implants prove scalable? https://chatgpt.com/share/69c85655-c24
How psychedelics push your brain to dream while awake https://theconversation.com/how-psychedelics-push-your-brain-to-dream-while-awake-new-study-276708 Now how to nudge the brain of blind people to see through sound-guided mental image…
Astrocytes connect specific brain regions through plastic networks (in mice) https://www.nature.com/articles/s41586-026-10426-6 "communication between distant brain regions that is mediated by plastic networks of gap junction-coupled astrocytes";
How psychedelics push your brain to dream while awake https://medicalxpress.com/news/2026-03-psychedelics-brain.html "psychedelics make the brain more likely to 'see' images from memory rather than what's actually in front of it"; mental imagery
Thus far about the only known advantage of a visual cortical prosthesis (brain implant for restoring vision) over visual-to-auditory sensory substitution is that you get to see blobs of light (phosphenes) if late-blind https://www.artificialvision.com/neuralink.htm
Brain-computer interfaces in healthcare: building the picks and shovels company while the giants fight over gold #BCI
IEEE Spectrum: At-home brain stimulation for depression is just the start https://spectrum.ieee.org/flow-neuroscience-tdcs-depression-fda "Flow's headset is the first tDCS device approved by the FDA", "a noninvasive, nondrug treatment option for depres…
Fortunately my brain is quite slow, so as long as I'm healthy I won't need an invasive BCI (brain implant) to output faster than I can type or talk (with or without AI), and I'll use a headset or smartglasses for AR/XR.
Sparring with ChatGPT AI: Pretend that you are Elon Musk, and you see that The vOICe is a formidable noninvasive competitor for a Neuralink Blindsight brain implant for the blind. What would you do? https://chatgpt.com/share/69a0798d-1b74-8004-8f08-fdeeeed4f046 🤔