2026-03-27 19:54:00
A brain implant for depression is about to be tested in humans #BCI
🧠 Bioengineered neuronal 'circuit board' mimics conditions of the human brain
#brain
The mature brain and the neuroscience of wisdom https://www.psychologytoday.com/us/blog/best-practices-in-health/202603/the-mature-brain-and-the-neuroscience-of-wisdom by William Haseltine; "A late-maturing bra…
🇺🇦 Auf radioeins läuft...
Flea:
🎵 Maggot Brain
#NowPlaying #Flea
#newRelease 🆕 album
https://officialflea.bandcamp.com/track/maggot-brain
https://open.spotify.com/track/3poJZBl2yoeWbMMxX63YcE
Revision Implant lands oversubscribed €4M round to take brain-powered sight implant into the clinic https://bmmagazine.co.uk/get-funded/revision-implant-4m-funding-brain-visual-prosthesis/ Brain implant for restoring vision to the blind;
fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…
That moment when it is 7:00am and you have it strongly in your brain that YOU HAVE A MEETING AT 8:00 AM... and yet your phone's calendar doesn't show it.
So... ASSUMING the calendar failed, as they do sometimes... you pull out your computer... and find the 8am appt is NOT there either...
... and then you remember that **YOU** MOVED IT TO MONDAY! 🤣🤦♂️
The good news is that I now have an hour more this morning for work than I thought I did an hour ago! 🤣
Brain computer interfaces boot up multipronged legal issues https://www.afslaw.com/perspectives/news/brain-computer-interfaces-boot-multipronged-legal-issues "BCIs may be implantable or noninvasive", "Can neural data ever …
I check out @… every now and then but I think I just don't like the format of short videos. It's sort of a jarring experience and (nothing against loops) I don't know if it's a good thing for my brain.
Contrast that to Pixelfed where it is still images, and there is a stillness to it... it's a image, no motion, no sound, and you can stare at …
Hey folx! You probably see a lot of stuff from other social networks mirrored to Mastodon, how about we do it the other way around?
Recently, I've starred to mirror my posts to Instagram, Reddit, and other platforms, and I've had quite the success. My biggest post on Instagram, which is just one screenshot of a Mastodon post, has 44.5k likes and 256k views. My
Spinning my brain up for our last day at PaxEast (my wife’s birthday is this weekend so have to finish prep)
Anyone on my socials happens to see me (very tall, black leather jacket, with matching harpy pins on collar) feel free to say “howdy!”
You know you're an Internet old timer if you remember Gene Ray, self described "Cubic and Wisest Human"
That's right, the infamous Time Cube! Look it up and try to comprehend such simple math with your oneist brain noobs :-)
wow, that #redButtonBlueButton thing fucks with my brain in ways i didn't expect.
https://xcancel.com/waitbutwhy/status/2047710215265730755
New York-based Probook, which is building an AI operating system for home service businesses, raised a $34M Series A led by a16z and a $6M seed led by Sequoia (Lily Mae Lazarus/Fortune)
https://fortune.com/2026/06/23/excl…
#theplaylistsuggestion The Main Monkey Business by Rush. And... Banana Brain by Die Antwoord. Oh, and this: https://www.dailymotion.com/video/x8jpcxc
Yes, it is. It also has this appalling change:
Sure, I know everyone (not really) loves git now. I have a GH account. I administer a Gitlab instance.
But I *USE* Subversion. It remains the definitive repository of the ASF software I work with and it’s how my brain works for version control.
Obviously I can still use svn in a shell. Most of my changes are very small, so vi and svn are fine. However, it is sad to see
"When every student in a class processes information through the same language model, they are learning to reason through the same system. This introduces a new threat vector on the developing mind.
The model's statistical biases become the student's default framing. The model's reasoning structure becomes the student's reasoning structure. LLMs homogenize not just language but also perspective and reasoning strategies. "
🇺🇦 #NowPlaying on KEXP's #SonicReducer
The Gears:
🎵 Teenage Brain
#TheGears
https://thedefog.bandcamp.com/track/fears-for-a-teenage-brain
https://open.spotify.com/track/2nuY8QtC890uJH9fCWuTAm
Brian Schottenheimer Opened the Door for Offense in 2026 NFL Draft https://insidethestar.com/brian-schottenheimer-opened-the-door-for-offense-in-2026-nfl-draft
Ccontrast Trump’s AI Jesus post with another Trump image that came into prominence last week:
As everyone else in the room is animated by concern for the fallen man’s well-being
—they’re elevating his legs to ensure that blood is flowing to his brain
—Trump is assuming the bored-to–petulant affect he normally shows when he’s not the center of attention.
He’s standing with his arms dangling at his side with his prepared remarks open on the desk in front of him.
He’…
AI at Meta: TRIBE v2 (Trimodal Brain Encoder), an #AI model of the human #brain, predicting neural responses to sight, sound and language https://aidemos.atmeta.com/tribev2/
Neuroscientists being “surprised” that the brain doesn’t work like a computer, episode 244:
https://www.nature.com/articles/d41586-026-01554-0
Non-Invasive Stimulation of the Brain Ended Opioid Addiction, Cigarette Craving - Slashdot
https://science.slashdot.org/story/26/06/26/221205/non-invasive-stimulation-of-the-brain-ended-opioid-addiction-cigarette-craving
Obsidian but free and with native MCP Server. Not tried but would be glad to be rid of obsidian
https://tolaria.md
Playing Terra Nil right now, and it's funny because from the promo stuff I thought I wouldn't like it much, yet I'm enjoying myself a lot. There's definitely a game design lesson to be leaned here.
I was absolutely correct in my assessment that the game feels like it's actively trying to make suspension of disbelief as hard as possible with its completely ridiculous mechanics that make absolutely zero sense. "That's... Not how that works at all!" Is basically playing on repeat in my brain.
Furthermore, the entire technosolutionist tenor of the game rubs me very much the wrong way. This compounds with the physics- and biology-defying (or perhaps -spiting) fictional layer in cases like the convenient magical radiation-absorbing buildings so that you can reverse radiation contamination with a few simple clicks to be extremely bad politics actually...
But... The mechanics do work together quite well to make interesting puzzles with good gameplay that includes satisfying variety and challenges. The art is wonderful, and the music and audio design are spot on. The the result of each level is immensely satisfying, and the pacing is excellent.
I guess the lesson I'm taking away from this is that really solid fundamentals can triumph over an absolute cacophony of ludonarrative dissonance. That doesn't mean that in every decision between ludonarrative harmony (or just straight up believability) and neat mechanics you should compromise towards mechanics, but it reinforces the idea that if you make the mechanics enjoyable in the abstract, players (or at least, players like me) will be willing to compromise a *lot* on whether it actually makes any sense for things to work that way.
I'm still bothered by the "use technology to fix everything" politics, which prevents this game from being one I'll enthusiastically recommend, but despite myself I am having a lot of fun with it.
#GameDesign #SolarPunk
No! No no brain, no brain. no brain. Toot toot toot toot [unintelligible] like-like-like-like YeAH toot. boost. toot. boost. toot. toot toot toot toot like-like-like-like mastodon no brain. mastodon no brain. boost-toot-boost-toot. never! never! never! brain. boost toot boost toot. Never think!
https://
OH: I'm convinced in my conspiracy monkey brain that some libertarians are getting funding from the GOP & DNC to be a distraction.
#Overheard
Can someone explain to me how the argument “ #LLMs only produce stochastically reasonable output ” is relevant or convincing?
Like… how do you think a human brain forms a sentence? Is this a straight-forward deterministic process? Does it matter?
I use tools and processes to verify my output and so does a coding agent.
I just don't get how this is an argument that would…
Aldon Smith's brain donated to CTE Center as family's attorneys investigate his death at age 36 https://www.foxsports.com/articles/wcbk/aldon-smiths-brain-donated-to-cte-center-as-familys-attorneys-invest…
"Your brain is on fire."
"How could you ever know?"
"From what comes out of it... for sure..."
#humor #idiocracy #BrainOnFire
Gotta Go
A show for people who are juggling family, work, relationships, and the never-ending to-do list that lives rent-free in your brain...
Great Australian Pods Podcast Directory: https://www.greataustralianpods.com/gotta-go/
💢 MRI scans reveal how the brain processes toxic workplace abuse
#mri
Heute, wie auch gestern, bin ich mit meinem alten Schatz, der Nikon D7200 und dem Sigma 150–600 unterwegs. Nach dem ganzen Schwall an Automatik-, Motiv- und Fokusprogrammen der hippen spiegellosen Systemkameras ist es so etwas wie ein Brain-Reset!
Eine Wohltat, sich mit den Basics der Fotografie zu beschäftigen. Keine Automatik, alles von Hand regeln und einstellen. Einfach den Moduswähler auf M stellen und selbst zu entscheiden, wie etwas auszusehen hat.
Ich geh dann mal malen … mit Licht!
Reading an article shared by a reputable source about accessible scrollable tables and the article indicates words that relate to the code by using color-coded underlines that are not links and my brain broke before I saw all the encoded px and LTR-only styles and yeah fine whatever close tab sigh.
Physical Intelligence says its new model, π0.7, can direct robots on tasks they weren't trained on, an "early sign" of generalization, surprising researchers (Connie Loizos/TechCrunch)
https://techcrunch.com/202…
Well, that's probably been the worst day for #Depression of the whole bloody year, but I did not get nothing done.
I finished an essay, and I think it's an important one.
https://www.
President, Extremely Normal Brain-Wise: Pope Weak On Crime, Also I'm Dr. Jesus Christ (Albert Burneko/Defector)
https://defector.com/president-extremely-normal-brain-wise-pope-weak-on-crime-also-im-dr-jesus-christ
http://www.memeorandum.com/260414/p150#a260414p150
Dad brains: How fatherhood rewires the male mind https://www.bbc.com/future/article/20260417-fatherhood-how-the-male-brain-and-body-prepare-for-childcare
Chlorpyrifos: Pesticide tied to brain damage in children, chronic disease and other health problems #environment
fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…
The “neural fingerprint” of psychedelics was spotted among hundreds of brain scans of people on LSD, psilocybin, DMT, mescaline and ayahuasca,
pointing to a shared impact on the brain’s behaviour.
The finding emerged from a major study that combined 11 brain imaging datasets from around the world
in an effort to build a reliable picture of how the substances temporarily rewire the brain.
Dr Danilo Bzdok and his colleagues analysed more than 500 brain scans from 267 p…
💧 Hydraulic brain: Body motion linked to fluid movement in the brain
#brain
New Study Challenges What We Know About Consciousness and the Brain
https://scitechdaily.com/new-study-challenges-what-we-know-about-consciousness-and-the-brain/
Visual prostheses (brain implants, retinal implants) for the blind typically require high contrast scenes for good results. AI depth mapping with foveal enlargement can help get around that https://play.google.com/store/apps/details?id=vOICe.vOICe AI depth view toggle in menu …
The vOICe vision BCI is an alternative for a Neuralink Blindsight brain implant. Recent developments include a live AI depth view https://www.youtube.com/watch?v=jE3ElPNA21g, AI scene description
fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…
"none of these legacy behaviours are rational. They arise out of that bundle of behaviours inherited from our two billion years of sexually selected ancestors... If our ancestors had not had these behaviours, we would not be here. Our ancestors were not, in the sense we mean here, rational... A purely rational being — a being created ab initio rational — would not have these behaviours.
No one is proposing to build an AI with a lizard brain. It won't happen."
Predicting visual mental imagery: structural and transcriptomic signatures in the human brain https://www.nature.com/articles/s42003-026-10309-6 "a distributed cortical architecture underlying VMI vividness" (VMI = visual mental imagery);
An interview with Galen Buckwalter, a BCI recipient in a Caltech brain implant study, on his recent ability to use the implant to produce musical tones (Emily Mullin/Wired)
https://www.wired.com/story/meet-the-man-making-music-with-his-brain-implant/
White paper and living document: Comparing The vOICe vision BCI with Neuralink Blindsight and other brain implants for restoring vision to the blind https://www.artificialvision.com/BCI.html
(YouTube video clips) Recent developments with The vOICe visual-to-auditory sensory substitution includ…
Intermittent fasting triggers surprising changes in the brain #health
Astrocytes connect specific brain regions through plastic networks (in mice) https://www.nature.com/articles/s41586-026-10426-6 "communication between distant brain regions that is mediated by plastic networks of gap junction-coupled astrocytes";
Researchers at Carnegie Mellon University have shown that
bacteria can learn from past experiences,
store memories across generations
and adapt their behavior to changing environments
all without a brain or nervous system
https://www.cmu.edu…
🤯 The brain region associated with moral inconsistency
#brain
When will @… write about Elon Musk's Neuralink Blindsight brain implant? Still nothing in sight. #BCI
I seem to have written a wee essay about #ArtificialGeneralIntelligence #AGI
It's probably not in its final form yet, I'll probably revise a bit. Comments welcome.
(YouTube) I don't have that white garden chair anymore, but The vOICe AI depth view would have made it still easier for Jens Naumann, blind former recipient of a Dobelle brain implant, to find the chair in my garden https://www.youtube.com/watch?v=0GsDfWqCMq
cintestinalis: Tadpole larva brain (C. intestinalis)
Entire connectivity matrix for the complete brain of a larva of Ciona intestinalis. Each directed edge represents a synaptic connection from pre-synaptic cell i to post-synaptic cell j (may not be a neuron). Edge weights represent the cumulative depth of presynaptic contacts in µm.
This network has 205 nodes and 2903 edges.
Tags: Biological, Connectome, Weighted
(YouTube, 2024) Towards a smart bionic eye https://www.youtube.com/watch?v=AhEEEyYAegA on the Orion I brain implant and AI, with Jason Esterhuizen; "It's sort of like learning a new language. And the closest I could explain what I see is like looking up at the stars at night."
Neuroscientists long theorized that bilingual speakers must process different languages with separate patterns of brain activity.
In a new study, however, researchers found that these patterns were more alike than had been expected.
When deciding how to make a word singular or plural, for instance,
bilingual people exhibit strikingly similar brain activity regardless of whether they are speaking in their first or second language.
“It wasn’t obvious that it was going to…
A three-dimensional micro-instrumented neural network device #NeuroTech
New 3D device harnesses living brain cells for computing
cintestinalis: Tadpole larva brain (C. intestinalis)
Entire connectivity matrix for the complete brain of a larva of Ciona intestinalis. Each directed edge represents a synaptic connection from pre-synaptic cell i to post-synaptic cell j (may not be a neuron). Edge weights represent the cumulative depth of presynaptic contacts in µm.
This network has 205 nodes and 2903 edges.
Tags: Biological, Connectome, Weighted
One of the world's top centers for brain science is taking a huge gamble on a tiny, transparent fish.
The Howard Hughes Medical Institute's Janelia Research Campus near Washington, D.C., has announcedan effort to use artificial intelligence and an unusual fish called Danionella to understand how the brain controls complex behaviors like social interaction.
Janelia plans to triple the space dedicated to fish to 6,000 square feet, which will make room for thousands of new t…
Brain rewires to stabilize walking during visual impairment https://neurosciencenews.com/brain-rewires-sensorimotor-walking-blindness-30721/
Resting-state functional magnetic resonance imaging study on the effects of visual status on walking-relate…
budapest_connectome: Budapest Reference Connectome 3.0
A parameterizable consensus brain graph, derived from connectomes of 477 people, each computed from MRI datasets of the Human Connectome Project. Nodes are brain regions, and edges are weighted by the number of "tracks" that run between two nodes, as well as fiber length, fractional anisotropy and the number of occurrences in each of the 477 individuals.
This network has 1015 nodes and 112890 edges.
Tags: Biol…
A computer model predicted which human brain implant channels would fail #invasive
Humans evolved to pay close attention to danger,
but today that instinct is being overwhelmed by an endless supply of bad news from around the world.
Researchers say the answer isn’t to stop following current events
—it’s to build healthier habits around how, when, and where we get our news.
https://www.
Brain-computer interfaces in healthcare: building the picks and shovels company while the giants fight over gold #BCI
budapest_connectome: Budapest Reference Connectome 3.0
A parameterizable consensus brain graph, derived from connectomes of 477 people, each computed from MRI datasets of the Human Connectome Project. Nodes are brain regions, and edges are weighted by the number of "tracks" that run between two nodes, as well as fiber length, fractional anisotropy and the number of occurrences in each of the 477 individuals.
This network has 1015 nodes and 121755 edges.
Tags: Biol…
Convicted Harvard scientist rebuilds career in China through controversial brain-computer interface lab https://thedebrief.org/convicted-harvard-scientist-rebuilds-career-in-china-through-controversial-brain-computer-i…
Ibogaine, a naturally occurring compound from a shrub native to Africa, is used to treat depression, anxiety, addiction, post-traumatic stress disorder and brain trauma.
Because it's illegal in the United States, Americans have been traveling to unregulated clinics, often in Mexico or the Caribbean, to take the drug.
Trump intends to sign the executive order as soon as this week, to allow its use in research
The administration doesn't plan to reclassify the drug …
Designing implants that don't scar the brain https://neurosciencenews.com/flexible-brain-implants-polyimide-biocompatibility-30538/ "Surprisingly, making probes 'ultra-thin' or allowing them to 'float' wirelessly didn't…
Sensory restoration via brain-computer interfaces: A unified 2×2 framework and convergence roadmap https://arxiv.org/html/2606.15091v1
"Community Siloing: Research remains siloed. Teams developing high-density invasive stimulation interfaces rarely collaborate with teams building non-invasive se…
Seeing and imagining are handled by the same brain cells https://www.simonsfoundation.org/2026/05/12/seeing-and-imagining-are-handled-by-the-same-brain-cells/
"Researchers make advances in understanding how human brains ar…
Why brain implants are more than a sci-fi fantasy #BCI
Max Hodak's Science Corp. is preparing to place its first sensor in a human brain https://techcrunch.com/2026/04/14/max-hodaks-science-corp-is-preparing-to-place-its-first-sensor-in-a-human-brain/ biohybrid
Companies developing brain implants for restoring vision to the blind will add smartglasses to compensate for ultra-crude vision, but smartglasses offering AI scene description, real-time talking OCR and sensory substitution may render the brain implant redundant. #BCI #blindness
#Paradromics: From brain implants to neuroprosthetics | Making sense of brain-computer interface terminology https://www.paradromics.com/insights/from-brain-implants-to-neuropr…
#MIRAGE: Robust multi-modal architectures translate fMRI-to-image models from vision to mental imagery https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.10142…
Frontal cortex organization supporting audiovisual processing during naturalistic viewing https://www.nature.com/articles/s41467-026-73947-8 "ventral division primarily processes auditory information and the dorsal division processes visual inputs", "this cortical orga…
Myelin emerges as an active regulator of brain plasticity, not only a structural insulator https://www.msn.com/en-us/health/other/myelin-emerges-as-an-active-regulator-of-brain-plasticity-not-only-a-struct…
#Paradromics and University of Michigan complete first #Connexus BCI implantation for the FDA-approved Connect-One clinical study
The brain's code seems to be in constant flux. Neuroscientists are baffled https://www.nature.com/articles/d41586-026-01554-0 "Neurons fire much more erratically than researchers thought." Required for "time stamping" of events for long-term memories?
Paralyzed artist paints again: how one brain implant drives two pathways to recovery #NeuroXess #BCI
Spatial transcriptomics on an expanded dataset at the brain-electrode interface: exploration of variability and identification of novel biomarkers https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2026.1852774/full "…
Intracortical BCI performance is robust to changes in attentional load during dual-tasking #NeuroPort
Simply sticking electrodes into primary visual cortex (V1) to evoke phosphenes ignores the feedback loops from higher visual areas back to V1. A Neuralink Blindsight brain implant will almost certainly perform very poorly. Engineering is one thing, biology/neuroscience another.
Implanted brain-computer interface functionality during nighttime in late-stage amyotrophic lateral sclerosis https://www.nature.com/articles/s41598-026-44228-7 "When applied to night data, daytime decoders caused unintentional BCI activations in 100% of nights."
China has approved the world's first invasive brain-computer chip - here's what's next https://www.technologyreview.com/2026/06/01/1138133/china-world-first-brain-chip/ (archived at
"We don't see with our eyes, we see with our brain" - Paul Bach-y-Rita https://www.seeingwithsound.com/BCI.html