2026-04-04 20:06:21
🤯 The brain region associated with moral inconsistency
#brain
🤯 The brain region associated with moral inconsistency
#brain
Intermittent fasting triggers surprising changes in the brain #health
Having screen-free time and mindful walks (or and other mindful activity) is great.
#mindfulness
https://www.theguardian.com/lifeandstyle/n
An interview with Galen Buckwalter, a BCI recipient in a Caltech brain implant study, on his recent ability to use the implant to produce musical tones (Emily Mullin/Wired)
https://www.wired.com/story/meet-the-man-making-music-with-his-brain-implant/
Remember the vacuum tube train? The car tunnels? The brain implant chip? The humanoid robots? Making government “efficient”? An AGI based on… tweets (wtf)?
But sure, colonizing Mars is totally real.
Think of the song that's the biggest ear worm to you lately.
Now thinking about an automatic body function that usually don't think about but is hard to ignore once you do.
Now think about that really awkward thing you said a long time ago that your brain brings up at 2 in the morning.
Goodnight >:3
China has approved the world's first invasive brain-computer chip - here's what's next https://www.technologyreview.com/2026/06/01/1138133/china-world-first-brain-chip/ (archived at
Sorry, brain fart and typo. Part of the problem with trying to do philosophy when mentally ill is I have a lot of brain fog, and can't really evaluate how good my ideas are.
However, when I typed 'survival', what I meant to type (and thought I had typed, was 'society'.
I find a form of active de-computing is one of the best ways to cope with the current exceeding world pain exhaustion & LLM brain drain around, i.e. doing more things offline, with your hands/body, being more present in your world, getting into crafts/materials, creating/fixing/mending things and sharing your lessons learned with others (in that sense quite in the spirit of open source culture).
To some this is may be just another form of entitled escapism, though I see it as activ…
About one in eight people globally have some form of sleep apnea.
Sleep apnea causes breathing to stop and start several times during sleep.
This happens because either your airway is blocked, known as obstructive sleep apnea,
or you brain isn’t controlling your breathing as it should, known as central sleep apnea.
For decades, the main form of treatment for this population has been the continuous positive airway pressure (CPAP) machine, which helps keep a person’s a…
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Cypress Hill:
🎵 Insane In The Brain
#NowPlaying #CypressHill
https://demloxx.bandcamp.com/track/cypress-hill-insane-in-the-brain-demloxx-remix
https://open.spotify.com/track/6DtVPEJXQxDp7nn3Kp076o
The Dissociated Universe: Bernardo Kastrup’s Analytic Idealism and the Mind That Contains the World
This essay completes a sequence. The first article considered Iain McGilchrist's panpsychist proposal that matter is a phase of consciousness, the way ice and vapor are phases of water. Its companion examined Daniel Dennett's illusionism, which argued that consciousness as we ordinarily conceive it is a user illusion the brain stages for itself. The third position, the…
Flourish, which is building Cortex AI, a brain-like synthetic intelligence system that uses less power than LLMs, raised $500M, including $100M from Jeff Bezos (Steven Levy/Wired)
https://www.wired.com/story/jeff-bezos-is-funding-a-wild-hunt-for-t…
fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…
I woke at 2am and it's now 3am and my brain is still swirling. Unlike my usual insomnia routine, I am choosing to read my masto feed in the hope that my brain changes direction and settles down. Good luck to anyone else awake and struggling to sleep.
I am currently discovering step by step the work of Mark Hallett :
https://www.thetransmitter.org/brain-stimulation/remembering-mark-hallett-leader-in-transcranial-magnetic-stimulation/
Quite a long journ…
For those who have been hearing of a Fly Brain being uploaded, the work you've been hearing of is impressive, yet as always the pop science media has warped what happened a bit:
„The Fly Brain Breakthrough Is Real. The “First Brain Upload” Narrative Is Not.”
https://…
Imagination is not just replaying what we see and hear https://www.sciencenews.org/article/imagination-perception-overlap-brain-neuroscience "Conjuring a nonspecific scene or sound pings brain networks that respond to more than one sense"
I'm getting stack frames corrupted (or else I'm hitting the wrong stack frames) and I can't see why. My brain is far too messed up to deal with this level of shit just now!
#PostScarcitySoftware
#TheJoyOfSoftwareEngineering
The first gene therapy for deafness earns FDA approval.
About sixty percent of all babies born deaf have some underlying genetic cause,
and mutations in the OTOF gene account for between 2 and 8 percent of them.
That gene encodes a protein called otoferlin, which enables hair cells inside the ear to transmit messages into the brain.
The OTOF gene is quite long, though, stretching about 90,000 bases of DNA.
This means it’s too long to ‘package’ inside a single vi…
A wandering mind is not the enemy of focus. It is the foundation of it. Your brain does not run on intensity. It runs on rhythm.
#NeuroScience
Nearly 300 studies link the common pesticide chlorpyrifos to multi-organ damage, DNA disruption, and chronic disease https://usrtk.org/healthwire/chlorpyrifos-multi-organ-damage-dna-disruption-and-chronic-disease/
"You wouldn't normally buy this pile of dogshit, but what if we mixed all this dogshit together with shit from other animals and put a pretty bow on it and called it a cupcake? Would you buy it then?"
https://beige.party/@maxleibman/116507984376346134
fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…
Brain prioritizes "sound offsets" during hearing repair https://neurosciencenews.com/auditory-repair-noise-damage-30639/
Noise-induced reduction and early recovery of superior paraolivary nucleus sound-offset responses
WATCH: Cowboys last-chance bookends getting Hall of Fame assist https://cowboyswire.usatoday.com/story/sports/nfl/cowboys/2026/06/03/tyron-smith-joins-cowboys-tackles-for-drill-work-at-otas/90395451007/
No brain today. Just be.
🇺🇦 #NowPlaying on KEXP's #SonicReducer
SUX:
🎵 Brain Dead
#SUX
https://suxmusic.bandcamp.com/track/brain-dead
https://open.spotify.com/track/2HFFo5hZInkgtfitv1azeK
EyeBrain: Left and Right Brain Lateralization Activity Classification Through Pupil Diameter and Fixation Duration
Ko Watanabe, Pooja Pol, Nicolas Gro{\ss}mann, Shoya Ishimaru, Andreas Dengel
https://arxiv.org/abs/2604.23562 https://arxiv.org/pdf/2604.23562 https://arxiv.org/html/2604.23562
arXiv:2604.23562v1 Announce Type: new
Abstract: The relationship between brain lateralization and cognitive functions is well-documented. The left hemisphere primarily handles tasks such as language and arithmetic, while the right hemisphere is involved in creative activities like drawing and music perception. Eye-tracking technology has shown the potential to reveal cognitive states by measuring ocular metrics such as pupil diameter and fixation duration. However, the ability to distinguish lateralized brain activity using these ocular metrics remains underexplored. Here, we demonstrate that pupil diameter and fixation duration can effectively classify left and right brain hemisphere activities. We obtained a considerably high classification performance, with an F1 score of 0.894. The results suggest that ocular metrics are robust indicators of lateralized brain activity and can be applied in cognitive monitoring and neurorehabilitation. Our future work expands on this by integrating these methods into real-time applications EyeBrain, potentially broadening their use across various cognitive and neurological domains.
toXiv_bot_toot
A shoutout to the systems engineers that made Microsoft Windows so fragile, that a single file browser (explorer.exe) freezing causes my Edge downloads to pause, and closing the frozen file browser closes all my file browsers.
My ADHD brain needed those open file browsers so I could keep track of all my in-progress tasks. How do I resume now? Yeah, I suppose I could come up with a better system than that.
(YouTube, 2025) The surprising way the brain is wired https://www.youtube.com/watch?v=9939jVJIZYo "What if vast areas of the brain contribute to many different functions and its connectivity is far more intricate than we once believed?"
Once more I have woken up with Killing Joke rattling around my brain.
Nine tenths of the law that is sick
Is possession
Life expressed in matter is a blasphemy
Success defined by acquisition stinks
So busy trying to make a living I forget about living, yes, I do
So busy trying to make a living, I forget about life
Thx Paul for a very informative and inspired Brain Inspired.
#neuroscience
💧 Hydraulic brain: Body motion linked to fluid movement in the brain
#brain
How US schools' overreliance on YouTube for educational content encourages students to drift into endless video scrolling on school-issued devices (Shalini Ramachandran/Wall Street Journal)
https://www.wsj.com/us-news/education/y…
🇺🇦 #NowPlaying on #BBC6Music's #GuyGarveysFinestHour
Chris Brain:
🎵 Kinds of Kindness
#ChrisBrain
Many years ago, a friend said he was following “The S Diet”. It was very simple and memorable:
——
No Sweets or Seconds, except on Saturday and Sunday.
——
Simple… easy… and it actually worked for me as a way to help maintain or reduce weight (along with some mild level of exercise).
My challenge is that in the intervening years, my brain fought that and changed it to:
——
No Sweets or Seconds, except on days ending in ‘y’.
——
🤣🤦♂️
Un-doin…
It's a week since my last #PostScarcitySoftware entry. The version of eval/apply copied from `0.0.6` still doesn't compile, let alone work. There are reasons. I've been ill — my brain really is fucked — and I've had urgent outdoor work.
There is progress. I am cleaning up bits of old cruft as I go. But I don't think copying the old code was a good decision. I…
Working in BCI: Culture, Purpose, & Vision #BCI #NeuroTech
Meta FAIR: KI-Zwilling für menschliche Neuronen
TRImodal Brain Encoder in zweiter Version veröffentlicht. Meta FAIR kann damit vorhersagen, wie das menschliche Gehirn reagiert.
https://www.heis…
A study in Nature Health finds that microplastics and nanoplastics
were at a higher level in brain tumour samples from living patients
than in healthy human brain samples from cadavers,
with a correlation between microplastic surface area and tumour proliferation. https://go.nature.com/4cuBK4I…
Massachusetts-based brain implant company Axoft raised a $55M Series A and says it tested its device in a Shanghai patient, with plans for more trials in China (Bloomberg)
https://www.bloomberg.com/news/articles/20…
One of those things about claims of “AGI” is that to really build a human-like intelligence we’d have to simulate a human brain as whole because 1. it’s the only thing we know that produces human intelligence and 2. no one knows how it actually works.
Because of (2) it’s irrelevant what anyone says about LLMs or any other technology (with the exception of simulating a whole brain)—you can’t know if a technology is intelligent like a human because we don’t know what that means or how that works.
Fun thing, it turns out it’s impossible to simulate a whole brain with the resolution required (basically quantum physics level), and you’d have to emulate a chemical and physical environment for the brain as well (it will also need a body etc.).
You’d also have to simulate other humans with brains from which the brain can learn; but to simulate those you’d have simulate evolving humans from single-cell organisms first etc etc ad infinitum
Study finds dangerous lead levels in children’s clothing #children
No! No no brain, no brain. no brain. Toot toot toot toot [unintelligible] like-like-like-like YeAH toot. boost. toot. boost. toot. toot toot toot toot like-like-like-like mastodon no brain. mastodon no brain. boost-toot-boost-toot. never! never! never! brain. boost toot boost toot. Never think!
https://
🧠 Bioengineered neuronal 'circuit board' mimics conditions of the human brain
#brain
A brain implant for depression is about to be tested in humans #BCI
cintestinalis: Tadpole larva brain (C. intestinalis)
Entire connectivity matrix for the complete brain of a larva of Ciona intestinalis. Each directed edge represents a synaptic connection from pre-synaptic cell i to post-synaptic cell j (may not be a neuron). Edge weights represent the cumulative depth of presynaptic contacts in µm.
This network has 205 nodes and 2903 edges.
Tags: Biological, Connectome, Weighted
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Flea:
🎵 Maggot Brain
#NowPlaying #Flea
#newRelease 🆕 album
https://officialflea.bandcamp.com/track/maggot-brain
https://open.spotify.com/track/3poJZBl2yoeWbMMxX63YcE
It probably says a lot about how my brain works that last night, I overheard a commercial featuring "I Saw the Sun" by Ace of Base, and immediately of Roger from American Dad.
https://www.youtube.com/watch?v=Fsrrf7P8Y_E
Triple Configuration of Brain Networks Based on Recurrent Neural Networks: The Synergistic Effects of Exogenous Stimuli, Task Demands, and Spontaneous Activity
Binghao Yang, Guangzong Chen
https://arxiv.org/abs/2604.23525 https://arxiv.org/pdf/2604.23525 https://arxiv.org/html/2604.23525
arXiv:2604.23525v1 Announce Type: new
Abstract: The foundation of cognitive flexibility and higher-order intelligence lies in the functional structure and activity of brain networks, which can be dynamically configured by both external environments and internal states. However, decoding these dynamics from high-dimensional neural data remains a challenge. In this study, we propose a computational framework using Recurrent Neural Networks (RNNs) with neural dynamic constraints to model source-localized resting-state EEG data from $114$ participants. We aim to clarify the "triple brain network configurations" driven by exogenous and endogenous factors, including external stimuli, information processing tasks, and spontaneous activities. Our model identifies the parietal network as a critical hub supporting these multiple configuration patterns. Furthermore, we reveal that the anterior and posterior parietal regions exhibit distinct functional specializations under different stimulus modalities. By formalizing a triple configuration framework, this work separates latent factors of brain dynamics and underscores the computational significance of parietal regions in orchestrating higher-order intelligence.
toXiv_bot_toot
The mature brain and the neuroscience of wisdom https://www.psychologytoday.com/us/blog/best-practices-in-health/202603/the-mature-brain-and-the-neuroscience-of-wisdom by William Haseltine; "A late-maturing bra…
💢 MRI scans reveal how the brain processes toxic workplace abuse
#mri
Would getting a Neuralink Blindsight brain implant for restoring vision be worth it? #BCI
As I emerge uncertainly from another sustained period of #madness, I realise (again) that I largely use the #PostScarcitySoftware project as self-prescribed anti-suicide therapy. It's sufficiently hard that it has my foggy brain working at full stretch, and sufficiently huge that there&…
The “neural fingerprint” of psychedelics was spotted among hundreds of brain scans of people on LSD, psilocybin, DMT, mescaline and ayahuasca,
pointing to a shared impact on the brain’s behaviour.
The finding emerged from a major study that combined 11 brain imaging datasets from around the world
in an effort to build a reliable picture of how the substances temporarily rewire the brain.
Dr Danilo Bzdok and his colleagues analysed more than 500 brain scans from 267 p…
Physical Intelligence says its new model, π0.7, can direct robots on tasks they weren't trained on, an "early sign" of generalization, surprising researchers (Connie Loizos/TechCrunch)
https://techcrunch.com/202…
fly_larva: Drosophila larva brain (2023)
A complete synaptic map of the brain connectome of the larva of the fruit fly Drosophila melanogaster. Nodes are neurons, and edges are synaptic connections, traced individually from brain image sections using three-dimensional electron microscopy–based reconstruction. Node metadata include the neuron hempisphere, hemispherical homologue, cell type, annotations, and inferred cluster. Edge metadata include the type of interaction (`'aa'`,…
If you compare the challenges that a Neuralink Blindsight brain implant for restoring vision still has to overcome with the challenges for The vOICe (sound-guided mental imagery)... https://www.artificialvision.com/neuralink.htm Supporting independent and open science
A geometry aware framework enhances noninvasive mapping of whole human brain dynamics
Song Wang, Kexin Lou, Chen Wei, Zhiyuan Sheng, Jiahao Tang, Kaining Peng, Xinke Shen, Shuhao Mei, Liang Chen, Dongfeng Gu, Quanying Liu
https://arxiv.org/abs/2604.25592 https://arxiv.org/pdf/2604.25592 https://arxiv.org/html/2604.25592
arXiv:2604.25592v1 Announce Type: new
Abstract: Non-invasive electrophysiology lacks methods that accurately reconstruct whole-brain spatiotemporal dynamics while incorporating individual cortical geometry, leaving current electroencephalography and magnetoencephalography source imaging limited by simplistic or biologically implausible priors. Here, we show that embedding participant-specific Geometric Basis Functions (GBFs), eigenmodes derived from each individual's cortical surface, provides a powerful anatomic constraint that resolves the inverse problem and improves reconstruction fidelity. The method reconstructs neural sources as linear combinations of geometric basis functions, thereby aligning source estimates with the geometric organization of neural dynamics. We validate GBF across the Meta-Source Benchmark, task-evoked data, resting-state networks, intracranial stimulation, and epilepsy data. The results demonstrate that GBF yields high localization accuracy and captures fast spatiotemporal dynamics consistent with anatomical pathways. These findings suggest that both spontaneous and evoked whole-brain activity can be described by hundreds of geometric modes, providing a compact yet accurate representation of neural sources. By linking cortical geometry to electrophysiological dynamics, GBF offers a versatile source imaging tool for both scientific and clinical applications.
toXiv_bot_toot
Chinese brain-computer interface startup Gestala raised $21.6M co-led by Guosheng Capital and Dalton Venture at a $100M to $200M valuation, per CEO Phoenix Peng (Kate Park/TechCrunch)
https://techcrunch.com/2026/03/11/bci-startu…
Microplastics may be quietly damaging your brain and fueling Alzheimer’s and Parkinson’s #health
Seeing with the Brain (not the eyes) #LGN (lateral geniculate nucleus) over visual cortex for a visual prosthesis.
Revision Implant lands oversubscribed €4M round to take brain-powered sight implant into the clinic https://bmmagazine.co.uk/get-funded/revision-implant-4m-funding-brain-visual-prosthesis/ Brain implant for restoring vision to the blind;
How Kosovo's tech industry, driven by local companies like business outsource provider SPEEEX, is helping cut youth unemployment and changing Pristina's skyline (Bloomberg)
https://www.bloomberg.com/news/articles/2026-04-30/…
Trying to draft a kind of "graphical abstract" on visual prosthesis BCI options... brain implants with electrodes, ultrasound with optogenetics or nanoparticles, and noninvasive visual-to-auditory sensory substitution. Suggestions for improvement? #neuroscience
It's not that The vOICe vision BCI is so good, it's that invasive BCIs for (restoring) vision are far worse than often claimed. The human brain is not plug-and-play. https://chatgpt.com/share/69f448a9-de04-83eb-9720-98a2f66ca7e5
A study of ~1,500 US workers finds AI use can reduce burnout but also cause "AI brain fry", a mental fatigue from using AI tools beyond one's cognitive capacity (Harvard Business Review)
https://hbr.org/2026/03/when-using-ai-leads-to-brain-fry
Paradromics blog post on intracortical BCIs vs. ECoG (electrocorticography) https://www.paradromics.com/blog/intracortical-versus-ecog-bci-modalities Note that for restoring vision, intracortical BCIs do not necessarily offer better performance than noninvasive…
How US schools' overreliance on YouTube for educational content encourages students to drift into endless video scrolling on school-issued devices (Shalini Ramachandran/Wall Street Journal)
https://www.wsj.com/us-news/education/youtube-…
US company Paradromics on brain-computer interfaces: China's recent developments and what they mean for the US https://www.paradromics.com/blog/china-bci-developments Seems at odds with how the US administration keeps eroding the scientific ecosystem in the US;
By linking up visual and auditory processing in the human brain, The vOICe vision BCI can act as both a fully noninvasive visual prosthesis for the totally blind and as a research vehicle for macroscopic neuroscience https://www.artificialvision.com/neuralink.htm
How psychedelics push your brain to dream while awake https://theconversation.com/how-psychedelics-push-your-brain-to-dream-while-awake-new-study-276708 Now how to nudge the brain of blind people to see through sound-guided mental image…
How psychedelics push your brain to dream while awake https://medicalxpress.com/news/2026-03-psychedelics-brain.html "psychedelics make the brain more likely to 'see' images from memory rather than what's actually in front of it"; mental imagery
Brain rewires to stabilize walking during visual impairment https://neurosciencenews.com/brain-rewires-sensorimotor-walking-blindness-30721/
Resting-state functional magnetic resonance imaging study on the effects of visual status on walking-relate…
Lucid dreaming shows that the human brain can go into a state of vivid mental imagery. If and once we can effectively tap into that, sound-guided mental imagery will restore veridical vision to the blind https://www.artificialvision.com/literature.htm
(YouTube) China's government-backed BCI push could bring brain-computer tech to the masses within 3 to 5 years #BCI
Designing implants that don't scar the brain https://neurosciencenews.com/flexible-brain-implants-polyimide-biocompatibility-30538/ "Surprisingly, making probes 'ultra-thin' or allowing them to 'float' wirelessly didn't…
Astrocytes connect specific brain regions through plastic networks (in mice) https://www.nature.com/articles/s41586-026-10426-6 "communication between distant brain regions that is mediated by plastic networks of gap junction-coupled astrocytes";
AI at Meta: TRIBE v2 (Trimodal Brain Encoder), an #AI model of the human #brain, predicting neural responses to sight, sound and language https://aidemos.atmeta.com/tribev2/
Brain-computer interfaces in healthcare: building the picks and shovels company while the giants fight over gold #BCI
Convicted Harvard scientist rebuilds career in China through controversial brain-computer interface lab https://thedebrief.org/convicted-harvard-scientist-rebuilds-career-in-china-through-controversial-brain-computer-i…
Why brain implants are more than a sci-fi fantasy #BCI
Low-level "visual" perception with visual-to-auditory sensory substitution is at least on par with brain implants for restoring vision. It's the higher-level visual perception where there remain many open questions. Much more scientific effort should go into that. #BCI #blindness
Brain-wide distributed processing underlying natural vision and audition https://www.biorxiv.org/content/10.64898/2026.05.26.727967v1 "prefrontal cortex coordinated brain dynamics through synergistic interactions independently of sensory modality and previous sensory e…
Seeing and imagining are handled by the same brain cells https://www.simonsfoundation.org/2026/05/12/seeing-and-imagining-are-handled-by-the-same-brain-cells/
"Researchers make advances in understanding how human brains ar…
To ChatGPT: Elon Musk focuses on scalable technologies, also for the upcoming Neuralink Blindsight brain implant for the blind. At some point these implants will start to fail in patients. Will Neuralink's handling of failing brain implants prove scalable? https://chatgpt.com/share/69c85655-c24
Article on the ReVision Implant brain implant originating from China (WeChat): WeChat #BCI #NeuroTech
Max Hodak's Science Corp. is preparing to place its first sensor in a human brain https://techcrunch.com/2026/04/14/max-hodaks-science-corp-is-preparing-to-place-its-first-sensor-in-a-human-brain/ biohybrid
Brain implants for restoring vision to the blind need to stimulate large numbers of neurons with electrodes, many times per second. So... https://bioniclab.substack.com/p/what-happens-to-blood-flow-when-you The stimulation paradox: Activating neurons starves them of…
The vOICe vision BCI app for Android crossed the 600,000 cumulative installs mark from Google Play https://play.google.com/store/apps/details?id=vOICe.vOICe Compare this to the number of Neuralink Blindsight brain implants in humans to date (spoiler: zero).
#Paradromics: From brain implants to neuroprosthetics | Making sense of brain-computer interface terminology https://www.paradromics.com/insights/from-brain-implants-to-neuropr…
Vision restoration: From prostheses to genetic-based brain-machine interfaces https://www.sciencedirect.com/science/chapter/handbook/abs/pii/B9780443222122000173 "Classically, visual prostheses were made of electrode arrays", in Handbook of …