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Decoding the Hot-Mitochondrion Paradox
Peyman Fahimi, Michael Lynch, Cherif F. Matta
https://arxiv.org/abs/2507.16824 https://arxiv.o…

Decoding the Hot-Mitochondrion Paradox
In a 2018 paper and a subsequent article published in 2023, researchers reported that mitochondria maintain temperatures 10-15 degrees higher than the surrounding cytoplasm - a finding that deviates by 5 to 6 orders of magnitude from theoretical predictions based on Fourier s law of heat conduction. In 2022, we proposed a solution to this apparent paradox. In the present perspective, we build upon that framework and introduce new ideas to further unravel how a biological membrane - whether of a…

This https://arxiv.org/abs/2310.09758 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_qbi…

Genome hybridization: A universal way for the origin and diversification of organelles as well as the origin and speciation of eukaryotes
The origin of organelles (mitochondrion, chloroplast and nucleus) remains enigmatic. The endosymbiotic hypothesis that chloroplasts, mitochondria and nuclei descend from the endosymbiotic cyanobacterium, bacterium and archaebacterium respectively is dominant yet uncompelling, while our discovery of de novo organelle biogenesis in the cyanobacterium TDX16 that had acquired the genome of its green algal host Haematococcus pluvialis disproves this hypothesis. In light of organelle biogenesis in th…