Tootfinder

Onkologie-Strategie: Nach Übernahme von Biotheus will Biontech Curevac kaufen
Biontech will den Konkurrenten Curevac aus Tübingen kaufen. Der Standort soll weiter eine wichtige Rolle spielen.

🍮 Wissen zum Nachtisch: 🍨
Retröt: Das #Klimaleugner und #Mythen Bullshit-Bingo.
#Familienfeiern können harmonisch sein – bis Onkel Herbert beim Thema

Das Klimaleugner und Mythen Bullshit-Bingo für Weihnachten und Familienfeiern
Weihnachten und hitzige Klimadiskussionen in der Familie? Wenn du absolut keinen Bock darauf hast, dann findest Du hier ein Klimaleugner-Bullshit-Bingo.

It's #NoKings day!
🚫👑🚫👑🚫👑🚫
Be loud. Be heard. Be safe.
⸻
EFF Protest Guide:
•⁠📱⁠https://mastodon.social/@eff/114678037068775207
Know Your Rights:
•⁠🚨⁠…

1/2 Paras (ok, ainoa) tänä vuonna lukemani EU:n tekoälyasetusta käsittelevä kirja on Tekoälyn sääntely (Susanna Lindroos-Hovinheimo, Ida Koivisto, Riikka Koulu, Suvi Sankari). Kirja esittelee asetuksen sisällön ja sisältää ajatuksia asetuksen epäselvistä ja ongelmallisista asioista, suhteista muuhun sääntelyyn, komission aseman reflektointia jne...

'RDW en Tesla omzeilden regelgeving bij goedkeuring Autopilot' - #Zembla - #BNNVARA
https://www…

Safety-Driven Response Adaptive Randomisation: An Application in Non-inferiority Oncology Trials
Maria Vittoria Chiaruttini, Lukas Pin, Sofia S. Villar
https://arxiv.org/abs/2506.08864

Safety-Driven Response Adaptive Randomisation: An Application in Non-inferiority Oncology Trials
The majority of response-adaptive randomisation (RAR) designs in the literature use efficacy data to dynamically allocate patients. Their applicability in settings where the efficacy measure is observable with a random delay, such as overall survival, remains challenging. This paper introduces a RAR design referred to as SAFER (Safety-Aware Flexible Elastic Randomisation) design, which uses early-emerging safety data to inform treatment allocation decisions in oncology trials. However, the desi…

VVD, NSC, BBB diskwalificeren zichzelf op een ongelofelijke wijze en laten zien dat het landsbelang bij hen niet bovenaan staat. En dan er ook nog heel erg blij mee zijn... (Van der Plas)
https://www.rtl.nl/nieuws/politiek/artikel

Coalitie: asielministerie wordt onderverdeeld over VVD, NSC en BBB
De leiders van VVD, NSC en BBB zijn het eens geworden over de verdeling van de opengevallen PVV-kabinetsposten. De portefeuille Asiel en Migratie wordt verdeeld tussen de drie partijen.

🇺🇦 Auf radioeins läuft...
Belle & Sebastian:
🎵 I'm A Cuckoo
#NowPlaying #Belle #Sebastian
https://lazybonkrecords.bandcamp.com/track/im-a-cuckoo
https://open.spotify.com/track/1OeMjL7ZnfsZbCizv1aAzQ

Pondering how to best prepare for the upcoming onslaught of Neuralink Blindsight brain implant hype/PR after the first blind patient receives one in UAE. Most scientists are open to reason, but they make up a tiny minority under funding stress, while the mass media profit from maximizing hype.
https://www.artifi…

Integrating tumor burden with survival outcome for treatment effect evaluation in oncology trials
Saurabh Bhandari, Michael J. Daniels, Chenguang Wang
https://arxiv.org/abs/2506.07387

Integrating tumor burden with survival outcome for treatment effect evaluation in oncology trials
In early-phase cancer clinical trials, the limited availability of data presents significant challenges in developing a framework to efficiently quantify treatment effectiveness. To address this, we propose a novel utility-based Bayesian approach for assessing treatment effects in these trials, where data scarcity is a major concern. Our approach synthesizes tumor burden, a key biomarker for evaluating patient response to oncology treatments, and survival outcome, a widely used endpoint for ass…