Tootfinder

Thread on today's 'red line' demonstration in The Hague. It's called the International city of peace and justice, but our government there has been extremely reluctant to criticize Israel for the genocide it is committing in Gaza. Let alone to take action: long overdue!
https://mastod…

My new mug is undefeated. May it long continue to be so.
#LFC

AmpLyze: A Deep Learning Model for Predicting the Hemolytic Concentration
Peng Qiu, Hanqi Feng, Barnabas Poczos
https://arxiv.org/abs/2507.08162 https://…

AmpLyze: A Deep Learning Model for Predicting the Hemolytic Concentration
Red-blood-cell lysis (HC50) is the principal safety barrier for antimicrobial-peptide (AMP) therapeutics, yet existing models only say "toxic" or "non-toxic." AmpLyze closes this gap by predicting the actual HC50 value from sequence alone and explaining the residues that drive toxicity. The model couples residue-level ProtT5/ESM2 embeddings with sequence-level descriptors in dual local and global branches, aligned by a cross-attention module and trained with log-cosh loss for robustness to assa…

Envisioning the Distance Ladder in the Era of the Habitable Worlds Observatory
Gagandeep Anand, Meredith Durbin, Rachael Beaton, Joseph Jensen, Adam Riess
https://arxiv.org/abs/2507.02056

Envisioning the Distance Ladder in the Era of the Habitable Worlds Observatory
The current state-of-the-art cosmic distance ladder requires three rungs--geometric distances, primary indicators, and Type Ia Supernovae--to achieve a 1% measurement of the Hubble constant $H_0$. The Habitable Worlds Observatory will have the sensitivity and resolution to reduce this to a two-step measurement, eliminating the third rung entirely and reaching into the Hubble flow with stellar distance indicators such as Cepheid variables and the tip of the red giant branch alone. We discuss the…

Fundamental Parameters for Totally Eclipsing Contact Binaries Observed by TESS
Xu Ding, KaiFan Ji, ZhiMing Song, XueFen Tian, JinLiang Wang, ChuanJun Wang, QiYuan Cheng, JianPing Xiong
https://arxiv.org/abs/2507.11838

Fundamental Parameters for Totally Eclipsing Contact Binaries Observed by TESS
Totally eclipsing contact binaries provide a unique opportunity to accurately determine mass ratios through photometric methods alone, eliminating the need for spectroscopic data. Studying low mass ratio (LMR) contact binaries is crucial for advancing our understanding of binary star evolution and the formation of rare optical transients known as red novae. We identified 143 totally eclipsing contact binaries from the Transiting Exoplanet Survey Satellite. These high-precision light curves reve…