Caliway CBL-514 combined with GLP-1 therapy reduced visceral fat by 367.4% more than GLP-1 monotherapy alone
CBL-514 is a first-in-class small-molecule injectable drug developed by Caliway Biopharmaceuticals. It acts as a lipolysis agent that induces adipocyte apoptosis (programmed cell death). While primarily investigated for aesthetic localized fat reduction and rare adipose disorders (Dercum’s disease), recent data suggests it may offer systemic metabolic benefits when combined with GLP-1 receptor agonists, specifically by targeting visceral fat and preventing weight rebound.
https://www.rapamycin.news/t/caliway-cbl-514-combined-with-glp-1-therapy-reduced-visceral-fat-by-367-4-more-than-glp-1-monotherapy-alone/23139
Virginia inches closer to gutting GOP seats through redistricting (Brakkton Booker/Politico)
https://www.politico.com/news/2026/01/16/virginia-redistricting-legislature-00733644
http://www.memeorandum.com/260116/p103#a260116p103
"London, San Francisco and Beijing achieve ‘remarkable reductions’ in air pollution"
#London #SanFrancisco #Beijing
UnitedHealth reduced hospitalizations for nursing home seniors. Now it faces wrongful death claims
https://www.theguardian.com/us-news/ng-interactive/2025/dec/17/unitedhealth-nursing-homes?CMP=share_btn_url
Sources: Apple partnered with Daily Mail in the UK soon after the Mail complained to the CMA in 2025 that Apple was stonewalling its attempts to join Apple News (Max Tani/Semafor)
https://www.semafor.com/article/02/15/2026/ap…
But I think that - first of all - Europe needs a strong cost reduction drive for components, systems, and processes in the energy transition, in a cooperation between R&D, manufacturers, and governments, and aligned with scaling up the market for 'made in Europe' solutions. We'll probably not get to the Chinese level, but we need to get a lot closer. This is essential both for competitiveness and affordability.
"EU sets binding 90% emissions reduction target for 2040"
#EU #EuropeanUnion #Emissions
Why the redistricting fight is likely to stretch beyond the 2026 midterms (Jane C. Timm/NBC News)
https://www.nbcnews.com/politics/elections/redistricting-fight-likely-stretch-2026-midterms-rcna253075
http://www.memeorandum.com/260115/p32#a260115p32
California GOP appeals their redistricting loss to Supreme Court in last-ditch bid to block voter-approved map (Yunior Rivas/Democracy Docket)
https://www.democracydocket.com/news-alerts/gop-appeals-their-california-redistricting-loss-to-supreme-court/
http://www.memeorandum.com/260115/p152#a260115p152