Tootfinder

Data highlight need to control cow outbreak to halt bird flu spread - STAT
https://www.statnews.com/2024/05/06/bird-flu-spread-study-of-h5n1-virus-infection-in-cows/?utm_campaign=rss

Study of cow tissues provides clues for unusual pattern of bird flu infections in dairy cattle
Location of receptors that flu viruses can attach to in cows may help explain pattern of illness in H5N1 bird flu outbreak in dairy cattle.

Regardless of what politicians want to make you think, Covid isn’t over.
You have a good chance (more with every infection) that you get permanently disabled (even with no symptoms at first).
You still main and kill and other people, and cause immense suffering by spreading it even if you personally don’t have symptoms.
Wear a fucking mask.

@… SO CUTE! My seven year old miniature poodle got a stomach infection for the first time ever this week, and proceeded to poop all over my house. Took him to the vet and he’s been better now after a special diet and antibiotics.

Between 2.5 and 28% of people infected with SARS-CoV-2 suffer Long COVID or persistence of symptoms for months after acute illness.
Many symptoms are neurological, but the brain changes underlying the neuropsychological impairments remain unclear.
This study aimed to provide a detailed description of the cognitive profile, the pattern of brain alterations in Long COVID and the potential association between them.

Brain and cognitive changes in patients with long COVID compared with infection-recovered control subjects
Serrano del Pueblo et al. report that patients with long COVID have cognitive difficulties, especially in episodic memory and executive function, compared

Qualitative analysis of a class of SIRS infectious disease models with nonlinear infection rate
Mengqi Tan
https://arxiv.org/abs/2403.04519 https://…

Qualitative analysis of a class of SIRS infectious disease models with nonlinear infection rate
The existence and local stability of some non-negative equilibrium points of a class of SIRS infectious disease models with non-linear infection and treatment rates are investigated under the condition that the total population is a constant. The qualitative theory of differential equations was used to demonstrate that the endemic equilibrium point of the system is either a stable equilibrium, an unstable equilibrium or a degenerate equilibrium under different circumstances. Subsequently, the l…

'It's real': Study suggests thousands of West Australians are suffering long-term COVID symptoms
"Researchers say more support is needed for patients suffering from long-term illness associated with a COVID-19 infection, with new data showing a large number of West Australians have been left unable to work due to their crippling symptoms. "

Experts call for more research into long COVID, as study reveals high prevalence in WA
While most have moved on from the coronavirus pandemic, a large cohort of people in Western Australia are still caught in its grip.

Ambient carbon dioxide concentration correlates with SARS-CoV-2 aerostability and infection risk
#covid19

Ambient carbon dioxide concentration correlates with SARS-CoV-2 aerostability and infection risk - Nature Communications
Carbon dioxide concentration has previously been used as a proxy for overall ventilation efficiency to indirectly estimate the risk of indoor SARS-CoV-2 transmission. Here, authors investigate whether the concentration of carbon dioxide also has a direct mechanistic role in improving transmission efficiency.

This https://arxiv.org/abs/2403.03205 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_mat…

Finding Super-spreaders in Network Cascades
Suppose that a cascade (e.g., an epidemic) spreads on an unknown graph, and only the infection times of vertices are observed. What can be learned about the graph from the infection times caused by multiple distinct cascades? Most of the literature on this topic focuses on the task of recovering the entire graph, which requires $Ω( \log n)$ cascades for an $n$-vertex bounded degree graph. Here we ask a different question: can the important parts of the graph be estimated from just a few (i.e.,…

"No Rest For The Wicked", "Infection Free Zone": Neue PC-Spiele im April 2024
Im April werden unter anderem "No Rest For The Wicked", "Sand Land" und "Infection Free Zone" veröffentlicht.

Ah, a Lactationally-Transmitted Infection (or disease). LTI (or LTD)
https://www.statnews.com/2024/04/30/h5n1-bird-flu-virus-cows-and-risk-to-people/

What we’re starting to learn about H5N1 in cows, and the risk to people
Questions about H5N1 for which there are pretty clear answers when it comes to birds are suddenly unsettled science in cows.

This https://arxiv.org/abs/2307.16767 has been replaced.
initial toot: https://mastoxiv.page/@arX…

Infection-induced Cascading Failures -- Impact and Mitigation
In the context of epidemic spreading, many intricate dynamical patterns can emerge due to the cooperation of different types of pathogens or the interaction between the disease spread and other failure propagation mechanism. To unravel such patterns, simulation frameworks are usually adopted, but they are computationally demanding on big networks and subject to large statistical uncertainty. Here, we study the two-layer spreading processes on unidirectionally dependent networks, where the sprea…

A mechanistic model for smallpox transmission via inhaled aerosols inside respiratory pathways
Saikat Basu, Abir Malakar, Mohammad Mehedi Hasan Akash
https://arxiv.org/abs/2403.04064

A mechanistic model for smallpox transmission via inhaled aerosols inside respiratory pathways
Investigations on airborne transmission of pathogens constitute a rapidly expanding field, primarily focused on understanding the expulsion patterns of respiratory particulates from infected hosts and their dispersion in confined spaces. Largely overlooked has been the crucial role of fluid dynamics in guiding inhaled virus-laden particulates within the respiratory cavity, thereby directing the pathogens to the infection-prone upper airway sites. Here, we discuss a multi-scale approach for mode…

This https://arxiv.org/abs/2305.13618 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_eco…

Rational social distancing in epidemics with uncertain vaccination timing
During epidemics people may reduce their social and economic activity to lower their risk of infection. Such social distancing strategies will depend on information about the course of the epidemic but also on when they expect the epidemic to end, for instance due to vaccination. Typically it is difficult to make optimal decisions, because the available information is incomplete and uncertain. Here, we show how optimal decision-making depends on information about vaccination timing in a differe…

This https://arxiv.org/abs/2403.03205 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_mat…

Finding Super-spreaders in Network Cascades
Suppose that a cascade (e.g., an epidemic) spreads on an unknown graph, and only the infection times of vertices are observed. What can be learned about the graph from the infection times caused by multiple distinct cascades? Most of the literature on this topic focuses on the task of recovering the entire graph, which requires $Ω( \log n)$ cascades for an $n$-vertex bounded degree graph. Here we ask a different question: can the important parts of the graph be estimated from just a few (i.e.,…

Bears great McMichael improving from infection https://www.espn.com/nfl/story/_/id/39553578/bears-great-steve-mcmichael-improving-staph-infection

Bears great Steve McMichael improving from staph infection - ESPN
Chicago Bears great Steve McMichael is improving after contracting a staph infection at a suburban hospital, and his family hopes he returns home early this week.

Findings, published Jan. 17 in Cell Stem Cell, show that dopamine neurons infected with SARS-CoV-2 stop working and send out chemical signals that cause inflammation.
Normally, these neurons produce dopamine, a neurotransmitter that plays a role in feelings of pleasure, motivation, memory, sleep and movement.
Damage to these neurons is also connected to Parkinson’s disease.
“This project started out to investigate how various types of cells in different organs respond to …

SARS-CoV-2 infection causes dopaminergic neuron senescence
Yang and colleagues demonstrate that SARS-CoV-2 can infect hPSC-derived midbrain dopamine (DA) neurons and induce cellular senescence. Several drug candidates were identified to rescue SARS-CoV-2 infection and DA neuron senescence. Inflammation and cellular senescence were also identified in substantia nigra tissue of COVID-19 patients.

Nou, dit mag wel in de krant.
WHO die eindelijk erkent dat #COVIDisAirborne .... en dat je daar wat mee (tegen) kunt doen ...
https://iris.who.int/bitst…

Serum samples from the fall of 2023 indicate a rise in protective antibodies in the youngest...This suggests that the children have regained some of protection lost after the pandemic. It also reflects the high prevalence of infection in the 2022/2023 season.

Person diagnosed with bird flu in Texas after contact with cows #BirdFlu
https://www.cbc.ca/news/health/texas-person-gets-bird-flu-1.7160508

Person diagnosed with bird flu in Texas after contact with cows | CBC News
A person in Texas has been diagnosed with bird flu, an infection tied to the recent discovery of the virus in dairy cows, health officials said Monday. The patient is being treated with an antiviral drug and their only reported symptom was eye redness, Texas health officials said.

“The humanized monoclonal antibody known as hu1F5, which specifically binds to the fusion (F) glycoprotein of both Nipah virus and Hendra virus and prevents virus infection of cells (neutralizes) has now proven effective in protecting against the often fatal Nipah virus in animal studies”

A monoclonal antibody targeting the fusion glycoprotein spike protects against deadly Nipah virus
The humanized monoclonal antibody known as hu1F5, which specifically binds to the fusion (F) glycoprotein of both Nipah virus and Hendra virus and prevents viru

This https://arxiv.org/abs/2306.13633 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_qbi…

Optimal Vaccination Policy to Prevent Endemicity: A Stochastic Model
We examine here the effects of recurrent vaccination and waning immunity on the establishment of an endemic equilibrium in a population. An individual-based model that incorporates memory effects for transmission rate during infection and subsequent immunity is introduced, considering stochasticity at the individual level. By letting the population size going to infinity, we derive a set of equations describing the large scale behavior of the epidemic. The analysis of the model's equilibria rev…

#Covid
Die UKHSA hat endlich Inzidenzschätzungen publiziert.
In den Grafiken dargestellt als 7-Tage-Summen.
https://www…

Winter Coronavirus (COVID-19) Infection Study: estimates of epidemiological characteristics, England and Scotland: 2023 to 2024
Modelled proportion of the population (prevalence) in England and Scotland currently infected with SARS-CoV-2 (COVID-19), incidence of new infections and the infection hospitalisation rate (IHR). Joint study with the Office for National Statistics.

Can anyone who understands statistics with regards to covid infection rates understand why the rating, which used to be from 1-10 in severity is now calculated at 1-20?
What does that mean when I see a rate 'high' - 5.3/20 in Nova Scotia? Would that have been 10.6/10 before? And therefore severe? Or 2.6/10 which would have only been elevated.
I'm no good at these things!
The original post from is here:
#CovidIsNotOver #statistics #covid @…
@…

He had a weakened immune system and ultimately succumbed to multi-organ failure from an infection.
This is what you do to other people when you run around in public without a mask on.
https://toot.earth/@PetaPixel/112197622736413184

My sons' music teacher contacted me to say that his return from his vacation was delayed by a Covid infection. He explained the timeline from first-symptom to first-negative-test, proactively affirmed that he'd be masking and running the air purifier I gave him, and gave the option to delay resumption of lessons.
I HELLA HEART THIS. Basic human decency. Common courtesy. Simple communication. It doesn't have to be difficult.

After feeling like crap most of the week I saw my doctor yesterday and I probably have a viral infection. I'm on medication, and I'm supposed to avoid the sun due to higher risk of sunburn. Also, I'll be in Palm Springs, CA all week, and there's a pool.

These 2 points taken together spell catastrophe:
"serious long-term outcomes often start to escalate around the 3rd infection"
"3.5 cumulative infections per person on average in the US so far
7.3 cumulative infections per person on average in the US by 2028"
https://

Mike Hoerger, PhD MSCR MBA (@michael_hoerger) on X
PMC COVID-19 Forecast, March 11, 2024 🧵1 of 3 🔹3.5 cumulative infections per person on average in the U.S. so far 🔹7.3 cumulative infections per person on average in the U.S. in four years, IF transmission continues according to the status quo of the linear trend 🔹Many…

Serum samples from the fall of 2023 indicate a rise in protective antibodies in the youngest...This suggests that the children have regained some of protection lost after the pandemic. It also reflects the high prevalence of infection in the 2022/2023 season.

Startling Discovery: COVID-19 Virus Can Stay in the Body More Than a Year After Infection
https://scitechdaily.com/startling-discovery-covid-19-virus-can-stay-in-the-body-more-than-a-year-after-infection/

Startling Discovery: COVID-19 Virus Can Stay in the Body More Than a Year After Infection
The COVID-19 virus can persist in the blood and tissue of patients for more than a year after the acute phase of the illness has ended, according to new research from UC San Francisco that offers potential clues to why some people develop long COVID. The scientists found pieces of SARS-CoV-2, ref

Diese Studie wurde offenbar mit #ChatGPT geschrieben und die Autoren haben es wohl versäumt, Korrektur zu lesen.
Finden den Fehler: 🤔 😉
"The Relationship Between Type and Position of Fungal Infection with Age and Gender"
#Science

One-Bit Total Variation Denoising over Networks with Applications to Partially Observed Epidemics
Claire Donnat, Olga Klopp, Nicolas Verzelen
https://arxiv.org/abs/2405.00619

One-Bit Total Variation Denoising over Networks with Applications to Partially Observed Epidemics
This paper introduces a novel approach for epidemic nowcasting and forecasting over networks using total variation (TV) denoising, a method inspired by classical signal processing techniques. Considering a network that models a population as a set of $n$ nodes characterized by their infection statuses $Y_i$ and that represents contacts as edges, we prove the consistency of graph-TV denoising for estimating the underlying infection probabilities $\{p_i\}_{ i \in \{1,\cdots, n\}}$ in the presence…

Bhattacharya and the other Great Barrington Declaration ghouls are a menace to public health. They should be shamed and shunned forevermore. https://mastodon.social/@taylorlorenz/112328639948379688

H5N1 in the US, 2/n
"Although the risk of infection from dairy products is very low, the worry is that the wider H5N1 spreads in cows, the more opportunities the virus has to adapt to transmit efficiently in mammalian hosts."
https://www.statnews.com/2024/04/25/h5n1-bird-flu-cows-outbreak-likely-widespread/

This https://arxiv.org/abs/2310.19481 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_qbi…

Spatial information allows inference of the prevalence of direct cell-to-cell viral infection
The role of direct cell-to-cell spread in viral infections - where virions spread between host and susceptible cells without needing to be secreted into the extracellular environment - has come to be understood as essential to the dynamics of medically significant viruses like hepatitis C and influenza. Recent work in both the experimental and mathematical modelling literature has attempted to quantify the prevalence of cell-to-cell infection compared to the conventional free virus route using …

Cost-Effective Activity Control of Asymptomatic Carriers in Layered Temporal Social Networks
Masoumeh Moradian, Aresh Dadlani, Rasul Kairgeldin, Ahmad Khonsari
https://arxiv.org/abs/2403.00725

Cost-Effective Activity Control of Asymptomatic Carriers in Layered Temporal Social Networks
The robustness of human social networks against epidemic propagation relies on the propensity for physical contact adaptation. During the early phase of infection, asymptomatic carriers exhibit the same activity level as susceptible individuals, which presents challenges for incorporating control measures in epidemic projection models. This paper focuses on modeling and cost-efficient activity control of susceptible and carrier individuals in the context of the susceptible-carrier-infected-remo…

He had a weakened immune system and ultimately succumbed to multi-organ failure from an infection.
This is what you do to other people when you run around in public without a mask on.
https://toot.earth/@PetaPixel/112197622736413184

Finding Super-spreaders in Network Cascades
Elchanan Mossel, Anirudh Sridhar
https://arxiv.org/abs/2403.03205 https://arxiv.org/pdf/2…

Finding Super-spreaders in Network Cascades
Suppose that a cascade (e.g., an epidemic) spreads on an unknown graph, and only the infection times of vertices are observed. What can be learned about the graph from the infection times caused by multiple distinct cascades? Most of the literature on this topic focuses on the task of recovering the entire graph, which requires $Ω( \log n)$ cascades for an $n$-vertex bounded degree graph. Here we ask a different question: can the important parts of the graph be estimated from just a few (i.e.,…

Years of flu symptoms, hives on and off traced to an exotic cause - The Washington Post
https://www.

Medical Mysteries: Years of hives and fevers traced to a startling cause
For 18 years a woman suffered from an episodic illness featuring hives and fevers that stumped doctors. The cause, discovered after surgery, was mind-blowing.

Back home and out walking the lovely Violet.
She's had a tough two weeks while I've been away - corn surgery on both back paws, a skin tag removed from the inside of an eyelid, and antibiotics for a sinus infection.
The old girl is looking great for her age though.
#Greyhounds #AdoptDontShop

I'm heartbroken to report that this poor little feral baby was too sick. She had advanced FIV and her body wasn't able to fight against an infection that was ravaging her. I can only draw comfort from knowing that we saved her from a lot of pain ending her days on the street.

A #Covid personal success story to report tonight:
My partner went to a family event over the long weekend, and her dad volunteered to take a RAT when the person who brought the infection interstate wouldn’t. Thank you!
Instead of complaining that we have to be lonely for a week, I’m grateful that I didn’t get infected today after she tested positive this morning. She was supposed t…

Double-stranded RNA activated caspase oligomerizer ( #DRACO ) technology, is an approach to ♦️selectively killing cells in which viral replication is taking place. ♦️
DRACO offered the promise of being broadly and rapidly effective for 🔸ending infection by many different viruses, and doing so with little adaptation of the core technology from virus to virus,🔸 a big improvement over the present state of…

This drug could be a game-changer for the human race
There are thousands of viruses in our world. But only about 220 are known to infect humans. Most people don’t understand how viruses work. They are not living things. They are very tiny packages of organic chemistry that get into an animal cell and...

Florida Dolphin Dies of Bird Flu as Alarm Grows Over Species Spread
https://gizmodo.com/first-bird-flu-infection-kills-florida-dolphin-source-1851439482

Florida Dolphin Dies of Bird Flu as Alarm Grows Over Species Spread
Florida scientists have reported the first known and fatal case of highly pathogenic H5N1 avian influenza in a bottlenose dolphin.

Precision nutrition to reset virus-induced human metabolic reprogramming and dysregulation (HMRD) in long-COVID - npj Science of Food
“SARS‐CoV‐2, the etiological agent of COVID-19, is devoid of any metabolic capacity; therefore, it is critical for the viral pathogen to hijack host cellular metabolic machinery for its replication and propagation. “

My sons' music teacher contacted me to say that his return from his vacation was delayed by a Covid infection. He explained the timeline from first-symptom to first-negative-test, proactively affirmed that he'd be masking and running the air purifier I gave him, and gave the option to delay resumption of lessons.
I HELLA HEART THIS. Basic human decency. Common courtesy. Simple communication. It doesn't have to be difficult.

Check out today's Metacurity for the top infosec developments you might have missed over the weekend, including
--'Hostile elements' tried to take over comms network on El Al flight
--Fulton County presumably paid LockBit ransom,
--Massive spam campaign hit Mastodon,
--Ukraine cops busted breached accounts seller,
--New NSO Group infection technique discovered,
--Russian hackers exploit Roundcube email server flaw,
--Wyze co-founder admits camera security issue,
--Russian hackers target Ukraine media outlets,
--Beam network lost $5m in phishing scam,
--much more
https://www.metacurity.com/p/hostile-elements-tried-take-comms-network-el-al-flight

No this is not allowed. I forbid it. I'm still trying to wrap my head around H5N1 and I'm not going to start thinking about another virus.
https://journa.host/@w7voa/112298810045194071

The post queries how incident response researchers obtain malware samples from infected machines, considering that some malwares delete the first file that triggers the infection and others tend to obscure the infection. https://reddit.com/r/cybersecurity/comments/1c3cky1/

Evaporation of bacteria-laden surrogate respiratory fluid droplets: On a hydrophilic substrate versus contact-free environment confers differential bacterial infectivity
Amey Nitin Agharkar, Dipasree Hajra, Durbar Roy, Vivek Jaiswal, Prasenjit Kabi, Dipshikha Chakravortty, Saptarshi Basu
https://arxiv.org/abs/2403.00004

Evaporation of bacteria-laden surrogate respiratory fluid droplets: On a hydrophilic substrate versus contact-free environment confers differential bacterial infectivity
The transmission of viruses/ bacteria cause infection predominantly via aerosols. The transmission mechanism of respiratory diseases is complex, including direct or indirect contact, large droplet, and airborne routes apart from close contact transmission. With this pretext, we have investigated two modes of droplet evaporation to understand its significance in airborne disease transmission; a droplet in a contact-free environment, which evaporates and forms droplet nuclei, and a droplet on a h…

#Food
Via The Hill @thehill
·
18h
#Tapeworms found in Florida man's brain linked to undercooked bacon, according to a report.
The condition is a rare parasitic infection of the brain that is strongly linked to pork consumption.

Super interesting stuff here: Haddrell, Allen, Henry Oswin, Mara Otero-Fernandez, Joshua F. Robinson, Tristan Cogan, Robert Alexander, Jamie F. S. Mann, Darryl Hill, Adam Finn, Andrew D. Davidson, and Jonathan P. Reid. 2024. "Ambient carbon dioxide concentration correlates with SARS-CoV-2 aerostability and infection risk." Nature Communications. vol. 15, no. 1. 2024/04/25. pp. 3487. [

"Vampire facials" at an unlicensed spa infected three people with HIV, CDC finds - CBS News
https://www.cbsnews.com/news/vampire-facial-hiv-new-mexico-infection-cdc/

This https://arxiv.org/abs/2309.12368 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_csHC_…

Rethinking Human-AI Collaboration in Complex Medical Decision Making: A Case Study in Sepsis Diagnosis
Today's AI systems for medical decision support often succeed on benchmark datasets in research papers but fail in real-world deployment. This work focuses on the decision making of sepsis, an acute life-threatening systematic infection that requires an early diagnosis with high uncertainty from the clinician. Our aim is to explore the design requirements for AI systems that can support clinical experts in making better decisions for the early diagnosis of sepsis. The study begins with a format…

All day, I've been meaning to do a #FollowFriday, but you know what? It's #LongCovidAwarenessDay, and -- since the ongoing pandemic that is in fact a mass disabling event is causing damage with every infection, with around a 1 in 10 chance of

This https://arxiv.org/abs/2305.07877 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_csLG_…

Differentiating Viral and Bacterial Infections: A Machine Learning Model Based on Routine Blood Test Values
The growing threat of antibiotic resistance necessitates accurate differentiation between bacterial and viral infections for proper antibiotic administration. In this study, a Virus vs. Bacteria machine learning model was developed to distinguish between these infection types using 16 routine blood test results, C-reactive protein concentration (CRP), biological sex, and age. With a dataset of 44,120 cases from a single medical center, the model achieved an accuracy of 82.2 %, a sensitivity of …

This is without a doubt, the most annoying poll I’ve ever seen here…🤦‍♂️
https://beige.party/@intransitivelie/112256221420351100

Covid reinfection stats, JN.1
New stats on how much protection one infection gives you against the next.
Short version: quite a bit of immunity in the first few months, dwindling back to nothing after a year.
This is specifically where the second infection was JN.1.
#covid #stats #JN1

Epidemic risk perception and social interactions lead to awareness cascades on multiplex networks
Tim Van Wesemael, Luis E. C. Rocha, Jan M. Baetens
https://arxiv.org/abs/2404.16466

Epidemic risk perception and social interactions lead to awareness cascades on multiplex networks
The course of an epidemic is not only shaped by infection transmission over face-to-face contacts, but also by preventive behaviour caused by risk perception and social interactions. This study explores the dynamics of coupled awareness and biological infection spread within a two-layer multiplex network framework. One layer embodies face-to-face contacts, with a biological infection transmission following a simple contagion model, the SIR process. Awareness, modelled by the linear threshold mo…

I'm heartbroken to report that this poor little feral baby was too sick. She had advanced FIV and her body wasn't able to fight against an infection that was ravaging her. I can only draw comfort from knowing that we saved her from a lot of pain ending her days on the street.

“Some 6.8% of American adults are currently experiencing long Covid symptoms, according to a new survey from the US Centers for Disease Control and Prevention (CDC)…
“More than three-quarters of the people with long Covid right now say the illness limits their day-to-day activity, and about one in five say it significantly affects their activities – an estimated 3.8 million Americans who are now experiencing debilitating illness after Covid infection.”

Computational Approaches of Modelling Human Papillomavirus Transmission and Prevention Strategies: A Systematic Review
Weiyi Wang, Shailendra Sawleshwarkar, Mahendra Piraveenan
https://arxiv.org/abs/2404.19235

Computational Approaches of Modelling Human Papillomavirus Transmission and Prevention Strategies: A Systematic Review
Human papillomavirus (HPV) infection is the most common sexually transmitted infection in the world. Persistent oncogenic Human papillomavirus infection has been a leading threat to global health and can lead to serious complications such as cervical cancer. Prevention interventions including vaccination and screening have been proved effective in reducing the risk of HPV-related diseases. In recent decades, computational epidemiology has been serving as a very useful tool to study HPV transmis…

Bears legend, Pro Football Hall of Famer Steve McMichael hospitalized due to infection amid ALS battle

https://www.cbssports.com/nfl/news/bears-l

This https://arxiv.org/abs/2309.07055 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_csCY_…

Unraveling the Geography of Infection Spread: Harnessing Super-Agents for Predictive Modeling
Our study presents an intermediate-level modeling approach that bridges the gap between complex Agent-Based Models (ABMs) and traditional compartmental models for infectious diseases. We introduce "super-agents" to simulate infection spread in cities, reducing computational complexity while retaining individual-level interactions. This approach leverages real-world mobility data and strategic geospatial tessellations for efficiency. Voronoi Diagram tessellations, based on specific street networ…

Probabilistic Zero Forcing with Vertex Reversion
Zachary Brennan
https://arxiv.org/abs/2404.15049 https://arxiv.org/pdf/2404.15049

Probabilistic Zero Forcing with Vertex Reversion
Probabilistic zero forcing is a graph coloring process in which blue vertices "infect" (color blue) white vertices with a probability proportional to the number of neighboring blue vertices. We introduce reversion probabilistic zero forcing (RPZF), which shares the same infection dynamics but also allows for blue vertices to revert to being white in each round. We establish a tool which, given a graph's RPZF Markov transition matrix, calculates the probability that the graph turns all white or …

From primary HPV infection to carcinoma in situ: a mathematical approach of cervical intraepithelial neoplasia
Vasiliki Bitsouni, Nikolaos Gialelis, Ioannis G. Stratis, Vasilis Tsilidis
https://arxiv.org/abs/2403.13302

From primary HPV infection to carcinoma in situ: a mathematical approach of cervical intraepithelial neoplasia
Cervical intraepithelial neoplasia (CIN) is the development of abnormal cells on the surface of the cervix, caused by a human papillomavirus (HPV) infection. Although in most of the cases it is resolved by the immune system, a small percentage of people might develop a more serious CIN which, if left untreated, can develop into cervical cancer. Cervical cancer is the fourth most common cancer in women globally, for which the World Health Organization (WHO) recently adopted the Global Strategy f…

Time-Since-Infection Model for Hospitalization and Incidence Data
Jiasheng Shi, Yizhao Zhou, Jing Huang
https://arxiv.org/abs/2403.12243 https://

Time-Since-Infection Model for Hospitalization and Incidence Data
The Time Since Infection (TSI) models, which use disease surveillance data to model infectious diseases, have become increasingly popular recently due to their flexibility and capacity to address complex disease control questions. However, a notable limitation of TSI models is their primary reliance on incidence data. Even when hospitalization data are available, existing TSI models have not been crafted to estimate disease transmission or predict disease-related hospitalizations - metrics cruc…

SIS epidemics on open networks: A replacement-based approximation
Renato Vizuete, Paolo Frasca, Elena Panteley
https://arxiv.org/abs/2403.16727 https://

SIS epidemics on open networks: A replacement-based approximation
In this paper we analyze continuous-time SIS epidemics subject to arrivals and departures of agents, by using an approximated process based on replacements. In defining the SIS dynamics in an open network, we consider a stochastic setting in which arrivals and departures take place according to Poisson processes with similar rates, and the new value of the infection probability of an arriving agent is drawn from a continuous distribution. Since the system size changes with time, we define an ap…

We show here that a significant increase in SARS-CoV-2 aerostability results from a moderate increase in the atmospheric carbon dioxide concentration (e.g. 800 ppm),
an effect that is more marked than that observed for changes in relative humidity.
We model the likelihood of COVID-19 transmission on the ambient concentration of CO2,
concluding that even this moderate increase in CO2 concentration results in a significant increase in overall risk.
These observations …

Ambient carbon dioxide concentration correlates with SARS-CoV-2 aerostability and infection risk - Nature Communications
Carbon dioxide concentration has previously been used as a proxy for overall ventilation efficiency to indirectly estimate the risk of indoor SARS-CoV-2 transmission. Here, authors investigate whether the concentration of carbon dioxide also has a direct mechanistic role in improving transmission efficiency.

Evaporation of bacteria-laden surrogate respiratory fluid droplets: On a hydrophilic substrate versus contact-free environment confers differential bacterial infectivity
Amey Nitin Agharkar, Dipasree Hajra, Durbar Roy, Vivek Jaiswal, Prasenjit Kabi, Dipshikha Chakravortty, Saptarshi Basu
https://arxiv.org/abs/2403.00004

Evaporation of bacteria-laden surrogate respiratory fluid droplets: On a hydrophilic substrate versus contact-free environment confers differential bacterial infectivity
The transmission of viruses/ bacteria cause infection predominantly via aerosols. The transmission mechanism of respiratory diseases is complex, including direct or indirect contact, large droplet, and airborne routes apart from close contact transmission. With this pretext, we have investigated two modes of droplet evaporation to understand its significance in airborne disease transmission; a droplet in a contact-free environment, which evaporates and forms droplet nuclei, and a droplet on a h…

#airborne
Revolutionary new terminology:
Infection "through the air" by "inhalation".
--> It's airborne.

Covid reinfection stats, JN.1 - stats geekery
The end-of-year stats even dip into the negative. Negative numbers for protection would mean one infection leaving people _more_ susceptible to the next.
But there weren't enough people in the study to consider that statistically proven. They give a range, like saying "roughly hereabouts", and only one side of the range dips negative.
So in reality, the previous infection could still have left some small level of protection after a year.
#covid

Die Krankheit "#Weizenbrand", verursacht durch einen Pilz, könnte sich unter dem Einfluss des Klimawandels verstärkt ausbreiten und ernsthafte Bedrohungen für die weltweite #Weizenproduktion darstellen. Aktuell sind bereits 6,4 Millionen Hektar

Production vulnerability to wheat blast disease under climate change - Nature Climate Change
The authors estimate the global vulnerability of wheat crops to wheat blast under current and future climates. They show that warmer, more humid climates can increase wheat blast infection, particularly in the Southern Hemisphere, subsequently reducing global wheat production.

Impact of Diffusion on synchronization pattern of epidemics in nonidentical metapopulation networks
Anika Roy, Ujjwal Shekhar, Aditi Bose, Subrata Ghosh, Santosh Nannuru, Syamal Kumar Dana, Chittaranjan Hens
https://arxiv.org/abs/2403.00681

Impact of Diffusion on synchronization pattern of epidemics in nonidentical metapopulation networks
In a prior study, a novel deterministic compartmental model known as the SEIHRK model was introduced, shedding light on the pivotal role of test kits as an intervention strategy for mitigating epidemics. Particularly in heterogeneous networks, it was empirically demonstrated that strategically distributing a limited number of test kits among nodes with higher degrees substantially diminishes the outbreak size. The network's dynamics were explored under varying values of infection rate. In this …

Fascinating: Estimating the impact of Non-pharmaceutical interventions (NPIs) for control of COVID mortality in the US using reductions in influenza mortality as an indicator of non-pharmaceutical infection control
https://www.medrxiv.org/content/10.1101/2024.03.06.…

Estimating the impact of public health interventions on COVID mortality in the United States using reductions in influenza mortality as an indicator of non-pharmaceutical infection control
Background Non-pharmaceutical interventions (NPIs) for control of COVID include a range of methods from masks to closures of schools and businesses with the efficacy of any individual strategy contingent on which other NPIs are employed and the extent of compliance with those strategies. In the case of a public health intervention, one typically looks at historical data for comparison, but, because COVID is a new disease, we have no such data. However, we do have extensive historical data for i…

I feel like more ire should be directed at our governments that have put us in this impossible situation, and less at people who are given no good options. Did we incentivize or require ventilation/filtration upgrades in public spaces? No. Did we educate people about masks? No. Did we continue pushing regular vaccinations? Not really. How about a long covid research moonshot? Meh.
People are selfish. That's not going to change, that's just human. Govern accordingly.

"Aside from what appears to be an extreme promotional campaign for a new Judge Dredd movie, Government social media used the V For Vendetta mask as an example of the kind of face covering not allowed, even though we have been encouraged to wear face masks to help reduce spread of infection, such face coverings have been common since SARS was a thing, some religious practices include face coverings, and there is more cosplay around than ever before, both comic con related, hen night rela…

⚕️ Rapid molecular testing in emergency department leads to faster, targeted treatment for community-acquired pneumonia
https://medicalxpress.com/news/2024-03-rapid-molecular-emergency-department-faster.html

Rapid molecular testing in emergency department leads to faster, targeted treatment for community-acquired pneumonia
Pneumonia is an inflammatory condition affecting the lungs, typically resulting from an infection with viruses or bacteria. Community-acquired pneumonia refers to pneumonia acquired outside of the health care system. It is one of the most common infectious diseases, significantly contributing to both mortality and morbidity on a global scale.

This https://arxiv.org/abs/2309.14583 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_mat…

On the dynamic behavior of the network SIR epidemic model
We study a susceptible-infected-recovered (SIR) epidemic model on a network of $n$ interacting subpopulations. We analyze the transient and asymptotic behavior of the infection dynamics in each node of the network. In contrast to the classical scalar epidemic SIR model, where the infection curve is known to be unimodal (either always decreasing over time, or initially increasing until reaching a peak and from then on monotonically decreasing and asymptotically vanishing), we show the possible o…

A complicated cast of immune and other characters may contribute to long COVID 
Morgan’s lab and others have zeroed in on immune proteins that defend us from bacteria and viruses.
These proteins, part of a defense called complement, circulate in the blood, and get chopped up during an infection. 
The resulting fragments sound a “we’re under attack” alarm and help form a molecular machine that busts pathogens.
Once the infection clears, the fragments fade away.
Bu…

The blood holds clues to understanding long COVID
A growing cadre of labs are sketching out some of the molecular and cellular characters at play in long COVID, a once-seemingly inscrutable disease.

The role of susceptible individuals in spreading dynamics
Chang Su, Fang Zhou, Linyuan L\"u
https://arxiv.org/abs/2403.08599 https://

The role of susceptible individuals in spreading dynamics
Exploring the internal mechanism of information spreading is critical for understanding and controlling the process. Traditional spreading models often assume individuals play the same role in the spreading process. In reality, however, individuals' diverse characteristics contribute differently to the spreading performance, leading to a heterogeneous infection rate across the system. To investigate network spreading dynamics under heterogeneous infection rates, we integrate two individual-leve…

Semi-Quantitative Analysis and Seroepidemiological Evidence of Past Dengue Virus Infection among HIV-infected patients in Onitsha, Anambra State, Nigeria
David Nwachukwu, Edith Nnenna Oketah, Chineze Helen Ugwu, Hope Chioma Innocent-Adiele, Chisom Chimbundum Adim, Euslar Nnenna Onu, Ann Onyinyechi Chukwu, Grace Aghaji Nwankwo, Mary Uche Igwe, Phillip O. Okerentugba, Iheanyi Omezuruike Okonko

Semi-Quantitative Analysis and Seroepidemiological Evidence of Past Dengue Virus Infection among HIV-infected patients in Onitsha, Anambra State, Nigeria
Despite its endemic nature as well as the recent outbreaks, information on the opportunistic DENV in Anambra state has been sparse. This study thus aimed to give seroepidemiological evidence of past dengue virus infection among HIV-infected patients in Onitsha, Anambra State, Nigeria. Plasma from 94 HIV-infected patients who were attending Saint Charles Borromeo Hospital, Onitsha in Anambra State, Nigeria was tested for IgG antibodies specific to the dengue virus by IgG ELISA assay. The prevale…

#Covid
Let's compare the UKHSA Winter CIS infection hospitalisation risks to my Zurich calibration.
Peak hospitalisations according to CH-SUR were about 700 per week, the maximum being in wks 48-50. CH-SUR covered an estimated 40% of beds at the time.
--> A 7d incidence of about 20.

Experts warn that a rare but dangerous bacterial infection is spreading at a record rate in Japan, with officials struggling to identify the cause.
The number of cases in 2024 is expected to exceed last year’s record numbers, while concern is growing that the harshest and potentially deadly form of group A streptococcal disease
– #streptococcal

The role of susceptible individuals in spreading dynamics
Chang Su, Fang Zhou, Linyuan L\"u
https://arxiv.org/abs/2403.08599 https://

The role of susceptible individuals in spreading dynamics
Exploring the internal mechanism of information spreading is critical for understanding and controlling the process. Traditional spreading models often assume individuals play the same role in the spreading process. In reality, however, individuals' diverse characteristics contribute differently to the spreading performance, leading to a heterogeneous infection rate across the system. To investigate network spreading dynamics under heterogeneous infection rates, we integrate two individual-leve…

Another covid erasure rant
Also from conversations at the dentist: staff don't test themselves regularly any more, but they do if they have respiratory symptoms!
There's a giant list of possible covid symptoms besides those! Like headache for example! Are we in a timewarp back to spring 2020?
It's really up in my face right now how weird the world is nowadays. No longer medical professionals' jobs to know even the basic facts necessary for infection control.
#CovidErasure #covid

#Covid
UKHSA Winter CIS estimates SARS2 hospitalisation risk.
Average risk: 0.45% (1 in 224)
Risk of individuals age 75 : 3.3% (1 in 30)
Cumulative infection incidence in England from Nov 14 until March 3 was 25%.
Mild, isn't it.

Covid reinfection stats - comment
I was just talking with someone yesterday about reinfections, contrasting the reality with the early hype.
"Yeah, I've had it - got that over with!"
And then
"Everybody get the vaccine so we can go back to normal!"
And at some point it dawned on people that might not have worked, & we got the expression "breakthrough infection" - even a special name at first, for this notable event!
No, people. You can just... keep getting it again.
#covid #WishfulThinking

A story of viral co-infection, co-transmission and co-feeding in ticks: how to compute an invasion reproduction number
Giulia Belluccini, Qianying Lin, Bevelynn Williams, Yijun Lou, Zati Vatansever, Mart\'in L\'opez-Garc\'ia, Grant Lythe, Thomas Leitner, Ethan Romero-Severson, Carmen Molina-Par\'is
https://arxiv.…

A story of viral co-infection, co-transmission and co-feeding in ticks: how to compute an invasion reproduction number
With a single circulating vector-borne virus, the basic reproduction number incorporates contributions from tick-to-tick (co-feeding), tick-to-host and host-to-tick transmission routes. With two different circulating vector-borne viral strains, resident and invasive, and under the assumption that co-feeding is the only transmission route in a tick population, the invasion reproduction number depends on whether the model system of ordinary differential equations possesses the property of neutral…

Alcohol intolerance may be linked to long COVID, specifically the post-viral fatigue syndrome (PVFS) type.
Long COVID refers to persistent symptoms that occur more than three weeks after the initial COVID-19 infection.
According to several anecdotal reports, alcohol intolerance, which is characterized by reactions like nausea, low blood pressure, fatigue, and dizziness when consuming alcohol, may be a unique symptom of long COVID.

Alcohol Intolerance After COVID: Symptoms, Causes, Treatment
Alcohol intolerance is not a common side effect of long COVID, but people have reported it happening to them.

A story of viral co-infection, co-transmission and co-feeding in ticks: how to compute an invasion reproduction number
Giulia Belluccini, Qianying Lin, Bevelynn Williams, Yijun Lou, Zati Vatansever, Mart\'in L\'opez-Garc\'ia, Grant Lythe, Thomas Leitner, Ethan Romero-Severson, Carmen Molina-Par\'is
https://arxiv.…

A story of viral co-infection, co-transmission and co-feeding in ticks: how to compute an invasion reproduction number
With a single circulating vector-borne virus, the basic reproduction number incorporates contributions from tick-to-tick (co-feeding), tick-to-host and host-to-tick transmission routes. With two different circulating vector-borne viral strains, resident and invasive, and under the assumption that co-feeding is the only transmission route in a tick population, the invasion reproduction number depends on whether the model system of ordinary differential equations possesses the property of neutral…

The World Health Organization has warned that dengue is rapidly becoming an urgent global health problem, with a record number of cases last year and outbreaks in places, such as France, that have historically never reported the disease.
In the United States, Dr. Gabriela Paz-Bailey, chief of the dengue branch at the division of vector-borne diseases at the Centers for Disease Control and Prevention, said that she expected high rates of dengue infection in Puerto Rico this year and th…

Brazil Has a Dengue Emergency, Portending a Health Crisis for the Americas
Record numbers of cases of the mosquito-borne virus have been reported in the Southern Hemisphere summer, and the surge is likely to move north.

Repetitive Infection Spreading and Directed Evolution in the Susceptible-Infected-Recovered-Susceptible Model
Hidetsugu Sakaguchi, Keito Yamasaki
https://arxiv.org/abs/2403.07034 …

Repetitive Infection Spreading and Directed Evolution in the Susceptible-Infected-Recovered-Susceptible Model
We study two simple mathematical models of the epidemic. At first, we study the repetitive infection spreading in a simplified SIRS model including the effect of the decay of the acquired immune. The model is an intermediate model of the SIRS model including the recruitment and death terms and the SIR model in which the recovered population is assumed to be never infected again. When the decay rate δof the immune is sufficiently small, the multiple infection spreading occurs in spikes. The mod…