Tootfinder

Rapid cardiac activation prediction for cardiac resynchronization therapy planning using geometric deep learning
Ehsan Naghavi, Haifeng Wang, Vahid Ziaei Rad, Julius Guccione, Ghassan Kassab, Vishnu Boddeti, Seungik Baek, Lik-Chuan Lee
https://arxiv.org/abs/2506.08987

Rapid cardiac activation prediction for cardiac resynchronization therapy planning using geometric deep learning
Cardiac resynchronization therapy (CRT) is a common intervention for patients with dyssynchronous heart failure, yet approximately one-third of recipients fail to respond due to suboptimal lead placement. Identifying optimal pacing sites remains challenging, largely due to patient-specific anatomical variability and the limitations of current individualized planning strategies. In a step towards constructing an in-silico approach to help address this issue, we develop two geometric deep learnin…

Fine-Tuning Large Audio-Language Models with LoRA for Precise Temporal Localization of Prolonged Exposure Therapy Elements
Suhas BN, Andrew M. Sherrill, Jyoti Alaparthi, Dominik Mattioli, Rosa I. Arriaga, Chris W. Wiese, Saeed Abdullah
https://arxiv.org/abs/2506.09707

Fine-Tuning Large Audio-Language Models with LoRA for Precise Temporal Localization of Prolonged Exposure Therapy Elements
Prolonged Exposure (PE) therapy is an effective treatment for post-traumatic stress disorder (PTSD), but evaluating therapist fidelity remains labor-intensive due to the need for manual review of session recordings. We present a method for the automatic temporal localization of key PE fidelity elements -- identifying their start and stop times -- directly from session audio and transcripts. Our approach fine-tunes a large pre-trained audio-language model, Qwen2-Audio, using Low-Rank Adaptation …

Commissioning, characterization and first high dose rate irradiations at a compact X-ray tube for microbeam and minibeam radiation therapy
Christian Petrich, Johanna Winter, Anton Dimroth, Thomas Beiser, Monika Dehn, Jessica Stolz, Jacopo Frignani, Stephanie E. Combs, Franz Schilling, Ghaleb Natour, Kurt Aulenbacher, Thomas E. Schmid, Jan J. Wilkens, Stefan Bartzsch

Commissioning, characterization and first high dose rate irradiations at a compact X-ray tube for microbeam and minibeam radiation therapy
Minibeam and microbeam radiation therapy promise improved treatment outcomes through reduced normal tissue toxicity at better tumor control rates. The lack of suitable compact radiation sources limits the clinical application of minibeams to superficial tumors and renders it impossible for microbeams. We developed and constructed the first prototype of a compact line-focus X-ray tube (LFXT) with technology potentially suitable for clinical translation of minibeams and microbeams. We give an ove…

‘May not arbitrarily deprive inmates of medications’: **Judge orders Trump admin to provide hormone therapy and ‘social accommodations’ to transgender federal prisoners**
https://lawandcrime.com/high-profile/may-not-arbitrarily-deprive-inmates-of-medications-judge-orders-trump-admin-to-provide-hormone-therapy-and-social-accommodations-to-transgender-federal-prisoners/

VChatter: Exploring Generative Conversational Agents for Simulating Exposure Therapy to Reduce Social Anxiety
Han Zhang, KaWing Tsang, Zhenhui Peng
https://arxiv.org/abs/2506.03520

VChatter: Exploring Generative Conversational Agents for Simulating Exposure Therapy to Reduce Social Anxiety
Many people struggle with social anxiety, feeling fear, or even physically uncomfortable in social situations like talking to strangers. Exposure therapy, a clinical method that gradually and repeatedly exposes individuals to the source of their fear and helps them build coping mechanisms, can reduce social anxiety but traditionally requires human therapists' guidance and constructions of situations. In this paper, we developed a multi-agent system VChatter to explore large language models(LLMs…

Nerd therapy. Opening old storage boxes of tech from the early 80s.
#ibmpc #dos #windows #80s

So, the kid who hacked the Finnish therapy clinic and caused so much pain is featured in an upcoming four-part HBO documentary.
https://variety.com/2025/tv/news/elon-musk-playstation-hacker-max-documentary-series-1236420579/

Elon Musk, PlayStation Hacker Subject of New Max Documentary Series
Max has dropped the first teaser for "Most Wanted: Teen Hacker," a documentary series that chronicles Finnish hacker Julius Kivimäki.

This https://arxiv.org/abs/2412.16309 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_qbi…

Stochastic Model of siRNA Endosomal Escape Mediated by Fusogenic Peptides in OVCAR-3
Gene silencing via small interfering RNA (siRNA) represents a transformative tool in cancer therapy, offering specificity and reduced off-target effects compared to conventional treatments. A crucial step in siRNA-based therapies is endosomal escape, the release of siRNA from endosomes into the cytoplasm. Quantifying endosomal escape is challenging due to the dynamic nature of the process and limitations in imaging and analytical techniques. Traditional methods often rely on fluorescence intens…

This https://arxiv.org/abs/2409.10879 has been replaced.
link: https://scholar.google.com/scholar?q=a

Primary Ionization and Particle Identification with Straw Tube Detectors
The charged particles are tracked in the high energy physics detectors to provide the information of their properties. One of the tracking detector is straw tube detector that has been used by many experiments. The motivation behind the current work is to study the primary ionization and particle identification using straw tube detectors. Additionally, we report the decay of $^{60}$CO for the study of gamma peaks since these are used in cobalt therapy, that is beneficial for cancer/tumor treatm…

This https://arxiv.org/abs/2501.13774 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_mat…

A mathematical model of CAR-T cell therapy in combination with chemotherapy for malignant gliomas
We study the dynamics and interactions between combined chemotherapy and chimeric antigen receptor (CAR-T) cells therapy and malignant gliomas (MG). MG is one of the most common primary brain tumor, with high resistance to therapy and unfavorable prognosis. Here, we develop a mathematical model that describes the application of chemo- and CAR-T cell therapies and the dynamics of sensitive and resistant populations of tumor cells. This model is a five-dimensional dynamical system with impulsive …

This https://arxiv.org/abs/2501.00553 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_nuc…

Angular differential and elemental fragmentation cross sections of a $400\,\text{MeV/nucleon}$ $^{16}\text{O}$ beam on a graphite target with the FOOT experiment
This paper presents the measurements of the angular differential cross sections for the forward production of He, Li, Be, B, C and N nuclei in the fragmentation process of a 400$\text{MeV/nucleon}$ $^{16}\text{O}$ beam interacting with a graphite target. Due to the limited data available in this energy regime, these measurements of nuclear fragmentation cross sections are relevant to improve nuclear interaction models for Particle Therapy and space radioprotection applications. The data analyze…

EXPOSURE THERAPY FOR INTERNET ADDICTED DEBATE PEOPLE
1. strap them to a chair, show them a mild take they disagree with by someone who's otherwise 99% aligned with their goals
2. watch them thrash angrily, unable to crash out on their socials, for the next 4 days
3. they settle, and think about this reaction after a week of being stuck there. they sheepishly set it aside in favor of teamwork
4. repeat with bigger and bigger issues until they have reasonable expec…

Today’s Marie’s biscuit day! Eggs bacon tea coffee. I’ll have therapy then head off to work. #TogetherBreakfast https://photos.app.goo.gl/5MnC3Y4w5FnwS1Gz8

@Snowshadow@mastodon.social
Would be a shame if the crazy red hat wearing health sites were reported
https://www.wtphealthcare.com/

We The People Health and Wellness Center | Primary Care | 959 East Venice Avenue, Venice, FL, USA
We The People Health and Wellness Center in Venice, Florida. Our DPC services offer transparent, affordable plans with unlimited telehealth visits for adults and pediatrics. Redefine your healthcare experience with IV Therapy, Red Light Therapy, Vitamin Shots, and Functional Medicine. Visit wtphealthcare.com for more. medical freedom, direct primary care, doctors that care, primary care, IV therapy, PRP therapy, massage therapy, red light therapy, pediatric care, vitamin shots, supplements.

A Positivity-Preserving Finite Element Framework for Accurate Dose Computation in Proton Therapy
Ben S. Ashby, Abdalaziz Hamdan, Tristan Pryer
https://arxiv.org/abs/2506.01105

A Positivity-Preserving Finite Element Framework for Accurate Dose Computation in Proton Therapy
We present a stabilised finite element method for modelling proton transport in tissue, incorporating both inelastic energy loss and elastic angular scattering. A key innovation is a positivity-preserving formulation that guarantees non-negative fluence and dose, even on coarse meshes. This enables reliable computation of clinically relevant quantities for treatment planning. We derive a priori error estimates demonstrating optimal convergence rates and validate the method through numerical ben…

Regenerating Daily Routines for Young Adults with Depression through User-Led Indoor Environment Modifications Using Local Natural Materials
Ziqun Hua, Ao Jiang, Haoling Yang, Hao Fan, Huizhong Hu, Bernard Foing
https://arxiv.org/abs/2506.05729

Regenerating Daily Routines for Young Adults with Depression through User-Led Indoor Environment Modifications Using Local Natural Materials
Young adults with depression often experience prolonged indoor stays, limiting their access to natural environments and exacerbating mental health challenges. While nature therapy is recognized for its psychological benefits, existing interventions frequently require outdoor engagement, which may not be accessible for all individuals. This study explores the potential of user-led indoor modifications using local natural materials as a mental health intervention. A qualitative approach wasemploy…

Diffusion Transformer-based Universal Dose Denoising for Pencil Beam Scanning Proton Therapy
Yuzhen Ding, Jason Holmes, Hongying Feng, Martin Bues, Lisa A. McGee, Jean-Claude M. Rwigema, Nathan Y. Yu, Terence S. Sio, Sameer R. Keole, William W. Wong, Steven E. Schild, Jonathan B. Ashman, Sujay A. Vora, Daniel J. Ma, Samir H. Patel, Wei Liu
https://…

Diffusion Transformer-based Universal Dose Denoising for Pencil Beam Scanning Proton Therapy
Purpose: Intensity-modulated proton therapy (IMPT) offers precise tumor coverage while sparing organs at risk (OARs) in head and neck (H&N) cancer. However, its sensitivity to anatomical changes requires frequent adaptation through online adaptive radiation therapy (oART), which depends on fast, accurate dose calculation via Monte Carlo (MC) simulations. Reducing particle count accelerates MC but degrades accuracy. To address this, denoising low-statistics MC dose maps is proposed to enable fas…

Quantum-Inspired Genetic Optimization for Patient Scheduling in Radiation Oncology
Akira SaiToh, Arezoo Modiri, Amit Sawant, Robabeh Rahimi
https://arxiv.org/abs/2506.04328

Quantum-Inspired Genetic Optimization for Patient Scheduling in Radiation Oncology
Among the genetic algorithms generally used for optimization problems in the recent decades, quantum-inspired variants are known for fast and high-fitness convergence and small resource requirement. Here the application to the patient scheduling problem in proton therapy is reported. Quantum chromosomes are tailored to possess the superposed data of patient IDs and gantry statuses. Selection and repair strategies are also elaborated for reliable convergence to a clinically feasible schedule alt…

The current cultural drive towards #nonmonogamy feels to me like gay conversion therapy. I feel somehow inadequate, defective and inferior by not wanting it, and under pressure to convert.
#sex #monogamy …

@Snowshadow@mastodon.social
Would be a shame if the crazy red hat wearing health sites were reported
https://www.wtphealthcare.com/

We The People Health and Wellness Center | Primary Care | 959 East Venice Avenue, Venice, FL, USA
We The People Health and Wellness Center in Venice, Florida. Our DPC services offer transparent, affordable plans with unlimited telehealth visits for adults and pediatrics. Redefine your healthcare experience with IV Therapy, Red Light Therapy, Vitamin Shots, and Functional Medicine. Visit wtphealthcare.com for more. medical freedom, direct primary care, doctors that care, primary care, IV therapy, PRP therapy, massage therapy, red light therapy, pediatric care, vitamin shots, supplements.

At my keynote for the 2025 Acadia Ethics Conference, a number of clinical therapists in attendance surprised me by embracing AI's potential to bridge mental health gaps and even flag anxiety-producing items in their offices from a single photo.
https://www.

Thermoplasmonics of Gold-Core Silica-Shell Colloidal Nanoparticles under Pulse Illumination
Julien El Hajj, Gilles Ledoux, Samy Merabia
https://arxiv.org/abs/2506.04835

Thermoplasmonics of Gold-Core Silica-Shell Colloidal Nanoparticles under Pulse Illumination
Core-shell nanoparticles, particularly those having a gold core, have emerged as a highly promising class of materials due to their unique optical and thermal properties, which underpin a wide range of applications in photothermal therapy, imaging, and biosensing. In this study, we present a comprehensive study of the thermal dynamics of gold-core silica-shell nanoparticles immersed in water under pulse illumination. The plasmonic response of the core-shell nanoparticle is described by incorpor…

If #BartSimpson and #ChrisGriffin Went to #CouplesTherapy, with #BobbyHill as the therapist.

Marie made biscuits, bacon egg tea coffee. Therapy day! Probably going to a couple things tonight. The busy part of the week is almost here! #TogetherBreakfast https://photos.app.goo.gl/ynozeBuDnMWGPigdA

PathGene: Benchmarking Driver Gene Mutations and Exon Prediction Using Multicenter Lung Cancer Histopathology Image Dataset
Liangrui Pan, Qingchun Liang, Shen Zhao, Songqing Fan, Shaoliang Peng
https://arxiv.org/abs/2506.00096

PathGene: Benchmarking Driver Gene Mutations and Exon Prediction Using Multicenter Lung Cancer Histopathology Image Dataset
Accurately predicting gene mutations, mutation subtypes and their exons in lung cancer is critical for personalized treatment planning and prognostic assessment. Faced with regional disparities in medical resources and the high cost of genomic assays, using artificial intelligence to infer these mutations and exon variants from routine histopathology images could greatly facilitate precision therapy. Although some prior studies have shown that deep learning can accelerate the prediction of key …

I opened the door to go to purchase something. Near the house, there are plenty of people talking to each other.
Social anxiety kicked in. I went back to my house.
With physical exercises and exposure therapy, my social anxiety is getting better and better.
But sometime, it still attacks me with full power. Well, at least now, I can smile (albeit still in high anxiety).
#SocialAnxiety

This https://arxiv.org/abs/2501.06125 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_mat…

Low-rank variance reduction for uncertain radiative transfer with control variates
The radiative transfer equation models various physical processes ranging from plasma simulations to radiation therapy. In practice, these phenomena are often subject to uncertainties. Modeling and propagating these uncertainties requires accurate and efficient solvers for the radiative transfer equations. Due to the equation's high-dimensional phase space, fine-grid solutions of the radiative transfer equation are computationally expensive and memory-intensive. In recent years, dynamical low-r…

Act now! Vote to ban the forced conversion therapy! You have not to go out only click the following link on the european website:
https://eci.ec.europa.eu/043/public/#/screen/home
Let's get out and vote now! Tell your friends, collegues and all supporters you know!
F…

When water phase matters: its effect on the stopping cross section for proton therapy and astrophysics
F. Matias, N. E. Koval, P. de Vera, R. Garcia-Molina, I. Abril, J. M. B. Shorto, H. Yoriyaz, J. J. N. Pereira, T. F. Silva, M. H. Tabacniks, M. Vos, P. L. Grande
https://arxiv.org/abs/2505.23396…

When water phase matters: its effect on the stopping cross section for proton therapy and astrophysics
Accurately quantifying the energy loss rate of proton beams in liquid water is crucial for the precise application and improvement of proton therapy, whereas the slowing down of proton in water ices also plays an important role in astrophysics. However, precisely determining the electronic stopping power, particularly for the liquid phase, has been elusive so far. Experimental techniques are difficult to apply to volatile liquids, and the availability of sufficient reliable measurements has bee…

This https://arxiv.org/abs/2505.18920 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_qbi…

Sensitivity analysis-guided model reduction of a mathematical model of pembrolizumab therapy for de novo metastatic MSI-H/dMMR colorectal cancer
Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide and the leading cause of cancer-related deaths in adults under 55, involving a complex interplay of biological processes such as dendritic cell (DC) maturation and migration, T cell activation and proliferation, cytokine production, and T cell and natural killer (NK) cell-mediated cancer cell killing. Microsatellite instability-high (MSI-H) CRC and deficient mismatch repair (dMMR) CRC constitute 15% of all CRC, and 4%…

Is GGAG:Ce@SiO$_2$-RB composite a prospective material for X-ray induced photodynamic therapy?
Iveta Terezie Ho\v{s}nov\'a, Krist\'yna Havlinov\'a, Jan B\'arta, Karol\'ina Mocov\'a, Xenie Lytvynenko, Lenka Prouzov\'a Proch\'azkov\'a, Vojt\v{e}ch Kazda, Franti\v{s}ek H\'ajek, Viliam M\'u\v{c}ka, V\'aclav \v{C}uba

Is GGAG:Ce@SiO$_2$-RB composite a prospective material for X-ray induced photodynamic therapy?
Nanocomposite material ($\mathrm{GGAG:Ce^{3+}@SiO_2-RB}$) for potential use in X-ray induced photodynamic therapy (X-PDT) was developed, thoroughly characterized, and evaluated. It consists of a scintillating $\mathrm{Gd_3(Ga_{1-x}Al_x)_5O_{12}:Ce^{3+}}$ core encapsulated in silica layer and functionalized with the photosensitizer Rose Bengal (RB). Radioluminescence measurements confirmed the energy transfer from the scintillating core to Rose Bengal. Dark toxicity and radiosensitisation effect…

Hybrid Machine Learning and Mathematical Modeling for Tumor Dynamics Prediction: Comparing SPIONs against mNP-FDG
Amit K Chattopadhyay, Aimee Pascaline N Unkundiye, Gillian Pearce
https://arxiv.org/abs/2505.21094

Hybrid Machine Learning and Mathematical Modeling for Tumor Dynamics Prediction: Comparing SPIONs against mNP-FDG
This is a Machine Learning guided study towards zone-specific ray therapy. Combining Machine Learning (Extreme Gradient Boosting) with continuum modeling (exponential and logistic growth), we find that while fluorodeoxyglucose-coated (mNP-FDG) can control cancerous tumor progression within 2 days compared to 18 days by Superparamagnetic Iron Oxide Nanoparticles (SPIONs), for complete termination of the tumor, SPIONS (20 days) are superior compared to mNP-FDG (more than 40 days). We also provide…

This https://arxiv.org/abs/2505.20358 has been replaced.
initial toot: https://mastoxiv.page/@arX…

Is GGAG:Ce@SiO$_2$-RB composite a prospective material for X-ray induced photodynamic therapy?
Nanocomposite material ($\mathrm{GGAG:Ce^{3+}@SiO_2-RB}$) for potential use in X-ray induced photodynamic therapy (X-PDT) was developed, thoroughly characterized, and evaluated. It consists of a scintillating $\mathrm{Gd_3(Ga_{1-x}Al_x)_5O_{12}:Ce^{3+}}$ core encapsulated in silica layer and functionalized with the photosensitizer Rose Bengal (RB). Radioluminescence measurements confirmed the energy transfer from the scintillating core to Rose Bengal. Dark toxicity and radiosensitisation effect…

The Use of Alendronate to Enhance Transcranial Transmission of Focused Ultrasound for Successful Ablations in Brain
G. Sakharova, A. Krokhmal, R. Galimova, A. Khatmullina, D. Nabiullina, I. Buzaev, D. Avzaletdinova, D. Chupova, V. Khokhlova
https://arxiv.org/abs/2505.24349

The Use of Alendronate to Enhance Transcranial Transmission of Focused Ultrasound for Successful Ablations in Brain
Objective: The aim of this study was to evaluate the efficacy of alendronate therapy in improving bone density distribution in skull bones and corresponding ultrasound permeability in patients who had previously experienced unsuccessful transcranial MR-guided focused ultrasound (MRgFUS) ablation. The ability of alendronate treatment to modify skull bone characteristics and enhance the success rate of repeat MRgFUS procedures was assessed. Methods: Five patients with initially unsuccessful MRg…

Stop Killing Games: https://eci.ec.europa.eu/045/public/#/screen/home
Make sure to also sign the conversion therapy ban if you haven’t yet, the more signatures the merrier: https://eci.ec.europa.eu/043/public/#/screen/home

This gives me hope in humanity.
Also gives me hope that if we got this much signatures (like 60% I think?) in just two days maybe we can still get the Stop Killing Games thing to pass too.
(Stop Killing Games: https://eci.ec.europa.eu/045/public/#/screen/home
Make sure to also sign the conversion therapy ban if you haven’t yet, the more signatures the merrier: https://eci.ec.europa.eu/043/public/#/screen/home )